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Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin? Darrell Miller 12/7/23
Support Healthy Gastroinesteinal Tract, Blood Sugar, And Cholesterol With Berberine Darrell Miller 11/8/22
The Health Benefits of Berberine Darrell Miller 9/12/22
A Vitamin Supplement Regime Can Mitigate Risk of Developing Pancreatic Cancer Darrell Miller 4/23/22
What is CBD? Darrell Miller 5/15/19
Drink matcha tea to enjoy these 6 health-boosting benefits Darrell Miller 4/30/19
Garlic the master medicine: Scientists find a compound in the herbthat can destroy resistant bacteria Darrell Miller 12/14/18
CBD helps relieve anxiety without the high Darrell Miller 6/7/18
What Is CBD Oil Really Used For? Darrell Miller 5/30/18
Is CBD Oil The Supplement That Your Workout Is Missing? Darrell Miller 5/29/18
4 Groundbreaking Studies on Cannabis and Disease Darrell Miller 11/17/17
Is CBD the Next Big Thing for Acne? Darrell Miller 7/19/17
New Study to Explore Benefits of CBD for Veterans with PTSD Darrell Miller 6/28/17
Cannabis prevents brain aging Darrell Miller 6/12/17
Consuming silicon-rich water or foods can purge your body of up to 70% of the of aluminum in your bloodstream Darrell Miller 4/8/17
Watch ANOTHER Man with Severe Parkinson’s Take Cannabis Oil to Settle his Tremors Darrell Miller 3/16/17
Vitamin C effective in targeting cancer stem cells Darrell Miller 3/12/17
Cannabis and Epilepsy Treatment Darrell Miller 1/30/17
Marijuana oil shows promise in treating epilepsy Darrell Miller 1/12/17
Protect yourself from flu season with these natural cold remedies Darrell Miller 12/11/16
Why Should We Take A Multi-Strain Probiotic? Darrell Miller 9/1/15
Homeopathic Remedies Darrell Miller 6/30/14
Is Coconut Oil A Brain Food? Darrell Miller 1/26/14
Impacts of pantethine Darrell Miller 1/9/14
How Does Tart Cherry Fight Gout? Darrell Miller 11/1/13
How Does Creatine Boost Muscle Strength? Darrell Miller 10/28/13
How Does Phosphatidyl Serine Improve Your Health? Darrell Miller 4/17/12
What is Fenugreek Seed and How Does It Boost Your Health? Darrell Miller 7/7/11
What is the Difference between Echinacea angustifolia and Echinacea purpurea? Darrell Miller 7/6/11
Does Boron Really Help Improve Bone Health? Darrell Miller 7/1/11
Can Dietary Collagen Help the Skin and Joint Tissue? Darrell Miller 6/30/11
What Makes a Good Joint Complex or Formula? Darrell Miller 6/29/11
Boost Brain Chemistry, Lower Bad Cholesterol, And More Darrell Miller 5/12/11
How Does Nattokinase Help Improve Cardiovascular Health Darrell Miller 4/29/11
Why is Maca Called the Peruvian Ginseng and What Does this Herb Do Darrell Miller 4/28/11
What is the Amino Acid Taurine and How Does It Boost My Health Darrell Miller 4/26/11
What is Oligonol Good for and How Does It Boost My Health? Darrell Miller 3/22/11
Is AHCC Good for the Immune System? How So? Darrell Miller 3/2/11
Gotu Kola And Memory Darrell Miller 9/15/09
Omega-3 Darrell Miller 7/8/09
Natural Vitamins under Attack Darrell Miller 6/29/09
Huperzine And Memory Darrell Miller 12/4/08
Phytoestrogen - Plant Estrogen Darrell Miller 9/25/08
Supplements to Fight Prostate Cancer Darrell Miller 7/29/07
Active Coenzyme Q10 Darrell Miller 7/7/07
ActiFruit with Cran-Max – Cleanse, Purify, and Protect the Urinary Tract* Darrell Miller 7/6/07
Breast Cancer and Natural Supplements Darrell Miller 5/11/07
Turmeric and Alzheimer’s Disease Darrell Miller 5/10/07
Learn about Bone Health! Darrell Miller 4/20/07
Complete Liver Cleanse Darrell Miller 4/19/07
D-Ribose Powder Benefits! Darrell Miller 4/10/07
Safe Solutions for Chronic Pain Darrell Miller 3/30/07
Regulating Blood Pressure Naturally Darrell Miller 3/28/07
Peppermint Oil for IBS Darrell Miller 3/24/07
Bio-Allers – All Natural Allergy Relief Darrell Miller 3/12/07
Revita Darrell Miller 3/8/07
What sets Sytrinol apart? Darrell Miller 2/27/07
Benefits - Supports joint function and tissue health* Darrell Miller 12/11/06
Q. How did research discover maitake’s health benefits? Darrell Miller 11/22/06
<B>Pycnogenol: Heart, Blood Sugar and Cellular Health</B> Darrell Miller 11/3/06
Slimaluma Plus – Appetite Control Darrell Miller 8/29/06
Remifemin symptomatic relief, scientifically supported* Darrell Miller 8/26/06
EczeMate from Source Naturals Darrell Miller 8/1/06
7-Syndrom Healing and 5-HTP Darrell Miller 6/7/06
The unique clinical benefits of Sun Chlorella Darrell Miller 3/25/06
Viterol A - Viatrozene gel 16% - reduce the signs of aging! Darrell Miller 2/25/06
Echinacea: why does it work in real life but not in trials? Darrell Miller 2/4/06
Cholesterol Support FAQ's Darrell Miller 1/6/06
Gr-8 Dophilus Darrell Miller 12/29/05
Gr-8 Dophilus - PROBIOTICS & DIGESTIVE SUPPORT Darrell Miller 12/29/05
Coenzyme Q10 and Cardiovascular Health. Darrell Miller 12/13/05
Life is more enjoyable when your stomach is prepared for it. Darrell Miller 11/28/05
Q. How did researcher discover maitake’s health benefits? Darrell Miller 11/11/05
Re: Benefits of Omega-3 Fatty Acids Darrell Miller 11/11/05
Omega-3 Fatty Acids - Part of Human diet for years. Darrell Miller 11/9/05
Research on SAMe.... Darrell Miller 10/26/05
All SAM-e supplements are not created equal Darrell Miller 10/26/05
PepZin GI™ helps relieve occasional discomfort. Darrell Miller 9/20/05
Pumpkin Seed Oil "Cucurbita pepo" Darrell Miller 8/18/05
Depressed? Try these “super 5” supplements Darrell Miller 8/9/05




Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?
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Date: December 07, 2023 12:12 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Did you know that glutathione is not only great for liver health, but it also promotes beautiful, radiant skin?

Glutathione (GSH), often considered as an amino acid but actually a tripeptide, is an antioxidant primarily synthesized in the liver. Composed of cysteine, glutamic acid, and glycine, it plays a crucial role in the synthesis and repair of DNA and protein, as well as the synthesis of prostaglandins. With its involvement in various functions like amino acid transport, toxin and carcinogen metabolism, immune system function, prevention of oxidative cell damage, and activation of enzymes, it is undoubtedly the most important tripeptide in the body.

While the benefits of supplementing with glutathione are numerous, two particularly compelling reasons are its positive impact on liver health and beautiful skin, which are the key focus of this article. However, before diving into the specifics of liver health and skin benefits, it's important to review the data on glutathione depletion and absorption.

GSH depletion can occur due to various oxidative stressors such as radiation, v.infections, enviro toxins, household chemicals, heavy metals, surgery, inflammation, burns, septic shock, and dietary deficiencies of GSH precursors and enzyme cofactors. Additionally, research suggests that GSH levels tend to decline with age.

The bioavailability of glutathione as a dietary supplement has encountered challenges in the past. Studies in the 1990s suggested that oral GSH might be inactivated by peptidases in the gut, as the levels of glutathione in the body did not seem to correlate with dietary intake, despite its presence in fruits, vegetables, and meats. Moreover, previous studies showed no significant increase in blood GSH levels when subjects were given high doses of 1,000-3,000 mg. As a result, alternative strategies like supplementation with NAC were used to boost GSH levels.

In 2014, something interesting happened that changed the way we look at the bioavailability of GSH. A groundbreaking study published in the Journal of Agricultural and Food Chemistry shed new light on the old research. This study showed that GSH, when taken in its intact form as OPITAC, a yeast-derived glutathione by Kohjin/Mitsubishi, can actually be rapidly transported across intestinal epithelial cells. Once inside, it gets rapidly converted into oxidized glutathione (GSSG) and accumulates in red blood cells and the liver, with only a small presence in plasma. So, although the GSH was indeed absorbed, it didn't show up in blood plasma because it transformed into GSSG and stored in the red blood cells and the liver. The bottom line is, supplementing with GSH is an effective way to boost GSH levels in the body.

This finding was further confirmed in another study that described how OPITAC, as a yeast-derived glutathione by Kohjin/Mitsubishi, is directly absorbed in its electrochemically reduced form in the intestine, then transported in the blood in bound forms, and eventually deposited into the liver in its reduced form.

But here's where it gets even more significant. A six-month randomized, double-blinded, placebo-controlled trial involving 54 adults was conducted to investigate the effects of oral GSH supplementation (250 or 1,000 mg/day, as OPITAC glutathione, Kohjin/Mitsubishi) on GSH levels in various parts of the body, including blood, erythrocytes, plasma, lymphocytes, and exfoliated buccal mucosal cells. The results were astounding. After one, three, and six months, GSH levels in blood increased significantly compared to baseline in both dosage groups. At the six-month mark, GSH levels skyrocketed 30-35 percent in erythrocytes, plasma, and lymphocytes, and a mind-boggling 260 percent in buccal cells in the 1,000 mg group (P < 0.05). Even in the low-dose group, GSH levels in blood and erythrocytes increased by 17 and 29 percent, respectively (P < 0.05). This research clearly demonstrates that supplementation with GSH is not only effective for increasing GSH levels in the body but also for maintaining them.

So, to sum it all up, the evidence speaks volumes - supplementing with GSH can have a profound impact on your body's GSH levels, and trust me, that's definitely a good thing!

Liver Health

When it comes to our well-being, the liver is a true superhero. Let's dive into some fascinating details about this essential organ.

Did you know that the liver is not only the largest reservoir of GSH (glutathione) but also a major site of GSH manufacture in the body? Pretty impressive, right? Special cells in the liver work tirelessly to synthesize GSH, which plays a crucial role in detoxification. Speaking of detoxification, the liver is a champion in this field. Its cells have sophisticated mechanisms to break down toxic substances, be it internal or external compounds.

During the detoxification process, the liver attaches or conjugates the toxins to water-soluble substances. This attachment makes the toxic molecules more water-soluble, less harmful, and easier to eliminate via urine or bile. In fact, glutathione conjugation produces water-soluble mercaptates that are excreted via the kidneys, effectively detoxifying acetaminophen and nicotine. Isn't it amazing how this process helps our bodies get rid of harmful substances?

But that's not all. Adequate levels of glutathione are crucial for the elimination of fat-soluble compounds, particularly heavy metals like mercury and lead. What's more, GSH serves as a cofactor for various peroxidase enzymes, aiding in the detoxification of peroxides generated from oxygen radical attacks on biological molecules. It also assists transhydrogenase enzymes in reducing oxidized centers on DNA, proteins, and other biomolecules. Talk about a multitasker!

The practical significance of this liver superhero was demonstrated in a study involving workers exposed to lead. A group of five workers received GSH at 200 mg/day for 30 days, while five others served as the control group. The results were striking. The group receiving GSH showed a significant increase in ALA dehydratase activity (which is inhibited by lead) compared to the control group (p < 0.05). This indicates that GSH could be a valuable solution for treating patients with lead poisoning.

So, let's take a moment to appreciate the remarkable liver and its incredible role in maintaining our health and well-being!

Alcohol Intoxication

Alcohol consumption is widely recognized for its capability to induce hepatic steatosis, also known as fatty liver disease, and disrupt biomembranes due to hepatic lipid peroxidation. This can lead to various lifestyle-related diseases and even hepatic cirrhosis by diminishing hepatic physiological function. Nevertheless, animal studies have shown that hepatic damage caused by alcohol intoxication can be mitigated by glutathione (GSH), a powerful antioxidant found in cells.

To further investigate the impact of GSH supplementation on the effects of alcohol intake, a human crossover comparative study was conducted. The study involved twenty healthy men and women who were grouped into three categories: placebo, 100 mg GSH (as OPITAC glutathione, Kohjin/Mitsubishi), and 30 mg curcumin. The study evaluated laboratory parameters, including breath alcohol concentration at different time intervals (20, 60, 120, and 180 minutes post-alcohol consumption) as measured by an alcohol checker. Additionally, subjective feelings were assessed through a questionnaire. During the study, all participants consumed whiskey in a quantity equal to their body weight multiplied by 1.25 mL, and were instructed to drink the entire sample within 10 minutes.

The results revealed that the breath alcohol concentration in the group supplemented with GSH significantly decreased compared to the placebo and curcumin groups at 20 (p<0.01), 60 (p<0.01), 120 (p<0.05), and 180 (p<0.08) minutes post-consumption. Furthermore, the GSH group reported lower levels of "sleepiness," "headache," and "upset stomach" in the subjective feeling questionnaire. Importantly, the concentration of aspartate aminotransferase (AST), an indicator of alcohol-induced organ damage, was significantly lower in the GSH group after two months compared to the placebo group.

The oral intake of GSH has demonstrated its effectiveness in reducing alcohol consumption-related stress and improving long-term hepatic function. These findings highlight the potential benefits of GSH supplementation in alleviating the detrimental effects of alcohol intoxication on the liver.

Nonalcoholic fatty liver disease

Nonalcoholic fatty liver disease (NAFLD) is a condition characterized by the build-up of fat in the liver of individuals who consume little or no alcohol. Unfortunately, NAFLD is quite common, affecting nearly one-third of all American adults. Interestingly, it often presents without readily apparent signs or symptoms, sometimes resulting in complications, and can lead to liver inflammation and scarring as the fat accumulates. Additionally, NAFLD is typically associated with conditions such as insulin resistance, central obesity, reduced glucose tolerance, type-2 diabetes, and elevated triglyceride levels.

Recognizing the substantial role glutathione (GSH) plays in phase 2 liver detoxification, a pilot trial was conducted to examine the therapeutic effects of GSH supplementation in patients with NAFLD. The trial included 29 individuals, and the patients were provided with daily oral supplementation of GSH at a dose of 300 mg (in the form of OPITAC glutathione, from Kohjin/Mitsubishi). The patients' clinical parameters were assessed before and after the GSH supplementation, and liver fat and fibrosis were quantified as well. The primary goal of the study was to determine any changes in alanine aminotransferase (ALT) levels. The results indicated a significant decrease in ALT levels following the GSH supplementation. Furthermore, triglycerides, non-esterified fatty acids, and ferritin levels also showed a reduction. This pilot study provides promising evidence for the potential therapeutic effects of oral glutathione administration, even at practical doses, in patients diagnosed with NAFLD. However, further investigation through large-scale clinical trials is necessary to validate its efficacy.

In summary, NAFLD is a prevalent condition with potential serious consequences, but studies like the aforementioned pilot trial shed light on potential treatment options such as GSH supplementation. The findings demonstrate the need for continued research in order to provide more conclusive evidence and expand our understanding of NAFLD management.

Beautiful Skin

By activating melanocytes in the skin, there is a notable increase in melanin formation, resulting in various blemishes such as freckles, pigmentation, and UV-induced skin spots, commonly known as age spots or liver spots. This is especially prominent after prolonged sun exposure and tanning. Age spots appear when melanin becomes concentrated or "clumped" in areas that have had years of frequent sun exposure. Luckily, there are materials like glutathione that can prevent or improve such pigmentation-related skin conditions.

Another aspect to consider is skin pigmentation, wrinkles, and pores. In a study conducted with eight women in their 30s or early 40s, each supplemented with 100 mg/day of GSH (as OPITAC glutathione, Kohjin/Mitsubishi) for two months, their skin conditions were evaluated using the Robo Skin Analyzer. Several parameters were analyzed, including skin brightness, the amount and area of skin pigmentation, number of pores, and number of wrinkles under the eyes. It was observed that all subjects' skin brightness improved when measured on the second day of the study. Additionally, over the course of the two months, both the amount and area of skin pigmentation decreased, leading to an improvement in blemishes and pigmentation. Not only did glutathione exhibit a whitening effect, but it also reduced the number of wrinkles under the eyes and minimized pores.

Furthermore, a randomized, double-blind, two-arm, placebo-controlled study was conducted with 60 otherwise healthy medical students. The purpose was to investigate whether supplementing with 500 mg of glutathione daily for four weeks would affect the skin melanin index compared to a placebo. Melanin indices were measured at six different sites on the body. The results demonstrated that melanin indices consistently decreased at all six sites in subjects who received glutathione after four weeks. The reductions were statistically significant compared to those who received the placebo at two sites: the right side of the face and the sun-exposed left forearm (p = 0.021 and 0.036, respectively). This improvement was likewise reflected in the reduction of UV spots. Importantly, both glutathione and placebo were well-tolerated. In conclusion, oral administration of glutathione leads to a lightening of skin color in the tested subjects.

Skin Lightening

Skin lightening is a process that is of interest to many individuals who seek to achieve a more even and radiant complexion. In recent studies, the use of a lozenge containing GSH 500 mg was explored as a means of skin lightening through an open-label, single-arm trial. The focus of this trial was to evaluate the buccal mucosa as a route for GSH administration and its potential in relation to skin lightening. It is worth noting that substances absorbed through the buccal route have the advantage of entering directly into the systemic circulation, effectively bypassing the gastrointestinal tract.

The trial involved thirty Filipino females with Fitzpatrick skin types IV or V who received a daily glutathione-containing lozenge for eight weeks. The results from this trial demonstrated a significant decrease in melanin indices from baseline to endpoint. What is fascinating is that this visible change became evident in as little as two weeks. It is important to highlight that during this trial, there were no recorded serious adverse events, and the laboratory examination findings remained normal. Based on these findings, the researchers concluded that the lozenge containing glutathione was deemed safe and effective in lightening the skin of Filipino women.

In addition to the aforementioned buccal route administration, another interesting approach that emerged from the studies is the topical application of GSH. A double-blind randomized clinical trial35 conducted in Yogyakarta, Indonesia, involved 74 healthy Indonesian women, with an average age of 33.3 ± 5.9 years, to explore the potential benefits of topical GSH. The trial subjects received supervised applications of facial wash twice a day, along with day cream containing sunscreen and night cream. The subjects were divided into three groups based on the active ingredients of the tested products, which included GSH (as OPITAC glutathione, Kohjin/Mitsubishi) at concentrations of 0.1 percent and 0.5 percent, and a control group without GSH.

Throughout the trial, the effects of the tested products on skin color and pigmentation were measured using colorimetry with Chromameter Minolta for L. Compared to the baseline measurements, there were significant increases in lightness (L) detected as early as week 2 for the group using GSH at 0.1 percent concentration. Interestingly, this increase was significantly higher compared to the group using GSH at the higher concentration of 0.5 percent, as well as the group without GSH. It is important to note that hyperpigmented lesions also showed improvement, particularly in the group using GSH at 0.5 percent concentration, which displayed superiority compared to the other groups at week 8. In conclusion, the skin care products containing GSH at 0.1 percent and 0.5 percent concentrations were found to be effective in lightening facial skin.

The findings from these studies shed light on the potential benefits of GSH in achieving skin lightening, either through buccal administration or topical application. It is worth noting that these studies focused on specific populations and more research is necessary to explore its effectiveness and safety across different skin types and ethnicities.

In summary, the administration of Glutathione sublingual clinically studiedglutathione, whether oral, buccal, or topical, has shown promising results in skin lightening and the improvement of complexion. Studies have demonstrated that glutathione not only enhances skin brightness but also reduces hyperpigmentation, wrinkles, and minimizes pores. Moreover, its effects have been evident in as little as two weeks, with a sustained impact over longer periods. These benefits were observed across a range of different skin types and ethnicities. However, it is important to highlight that these findings are based on specific populations, and more research needs to be conducted to confirm the consistency of these effects across a broader spectrum of skin types and ethnicities. The studies have also confirmed that the usage of glutathione is well-tolerated with no serious adverse effects reported.

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Support Healthy Gastroinesteinal Tract, Blood Sugar, And Cholesterol With Berberine
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Date: November 08, 2022 05:37 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Support Healthy Gastroinesteinal Tract, Blood Sugar, And Cholesterol With Berberine

Berberine is a substance that has been shown in clinical studies to support multiple body systems. It is found in the roots, stems, and bark of certain plants and has a long history of traditional use. Berberine supplements are a convenient way to get the benefits of this substance, and they can support gastrointestinal health, healthy blood glucose levels, and healthy blood cholesterol levels.* Let's take a closer look at the benefits of berberine.

Gastrointestinal Health

Berberine has been shown in human clinical trials to support gastrointestinal health. This is likely due to the fact that it can help regulate the growth of certain bacteria in the gut.* In addition, berberine has been shown to stimulate production of mucus, which can help protect the gut lining.*

Blood Glucose Levels

Several clinical trials have demonstrated that berberine can help support healthy blood glucose levels.* This is likely due to the fact that berberine can help improve insulin sensitivity and decrease insulin resistance.* In addition, berberine can help stimulate production of glucose-6-phosphate dehydrogenase (G6PD), an enzyme important for regulating blood sugar levels.*

Blood Cholesterol Levels

Clinical trials have also demonstrated that berberine supplementation can help support healthy blood cholesterol levels already within the normal range.* This is likely due to the fact that berberine can help decrease low-density lipoprotein (LDL) cholesterol and increase high-density lipoprotein (HDL) cholesterol.*

As you can see, there are many reasons to consider adding a berberine supplement to your daily routine. If you are looking for a convenient way to support gastrointestinal health, healthy blood glucose levels, and healthy blood cholesterol levels,* a berberine supplement may be right for you. As always, be sure to talk to your healthcare provider before starting any new supplement regimen.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6562)


The Health Benefits of Berberine
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Date: September 12, 2022 04:22 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: The Health Benefits of Berberine

Berberine is a natural constituent of herbs such as goldenseal, Oregon grape, and barberry. Clinical studies have demonstrated that berberine helps to support already normal glucose and lipid metabolism.* Because berberine is known for its limited bioavailability, this product includes caprate (C10, a medium-chain triglyceride) to promote optimal absorption and maintenance of gastrointestinal comfort during berberine supplementation.*

Berberine has a long history of use in Traditional Chinese Medicine and Ayurveda for supporting already normal liver function and healthy digestion.* It is also one of the most well-studied botanicals for already normal glucose metabolism support, with research indicating it may work by activating an AMPK-dependent pathway.*

Berberine May Help To Support Normal Glucose Metabolism*

Berberine is a plant alkaloid with a long history of use in Traditional Chinese Medicine for promoting already normal liver function.* extraction process ensures a consistent level of berberine from batch to batch. In addition, this product provides 500 mg of berberine hydrochloride per vegetarian capsule.

Several clinical studies have demonstrated that berberine can help to support normal glucose metabolism in already healthy individuals when taken at dosages of 900 mg to 1,500 mg per day.* In a placebo-controlled human clinical trial involving subjects with prediabetes who were given 500 mg of berberine two times daily for 12 weeks, researchers observed improvements in already normal fasting blood sugar, HbA1c, and triglyceride levels (as well as increases in HDL-cholesterol) compared to placebo group.*

May Also Help To Support Lipid Metabolism*

In addition to its effects on already normal glucose metabolism, berberine has also been shown to help support lipid metabolism in already healthy individuals. In a 12-week, double-blind, placebo-controlled human clinical trial involving subjects with mild elevations in LDL cholesterol who were given 500 mg of berberine two times daily, researchers noted statistically significant decreases in total cholesterol and LDL cholesterol levels (along with increases in HDL cholesterol) compared to placebo group.*

Berberine is a potent botanical extract that has been traditionally used for supporting liver function and healthy digestion. Additionally, it is one of the most well studied botanicals for supporting already normal glucose metabolism. Numerous clinical trials show that it can help maintain already normal levels of fasting blood sugar as well as HbA1c and triglycerides. Furthermore, berberine has also been shown to promote already healthy lipid metabolism by supporting already normal levels of total cholesterol, LDL cholesterol, and HDL cholesterol. Therefore, if you are looking for an herbal supplement to support your overall health and well being, berberine is definitely worth considering.

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6443)


A Vitamin Supplement Regime Can Mitigate Risk of Developing Pancreatic Cancer
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Date: April 23, 2022 11:49 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: A Vitamin Supplement Regime Can Mitigate Risk of Developing Pancreatic Cancer

Did you know that pancreatic cancer is the 4th leading cause of cancer-related death in the United States? It's a terrible disease, and unfortunately, it is often diagnosed too late for effective treatment. But what if there was something you could do to reduce your risk of developing pancreatic cancer? Believe it or not, there may be! A recent Chinese study has shown a clear correlation between higher intake of vitamins and lower risk of pancreatic cancer. The researchers believe that the vitamins induce apoptosis in cancer cells, thus preventing them from growing and spreading. So if you're looking for ways to improve your health, start by adding some vitamins to your diet!

What is pancreatic cancer?

Pancreatic cancer is a type of cancer that starts in the pancreas. The pancreas is a gland located in the abdomen behind the stomach. It produces enzymes that help with digestion and hormones that help regulate blood sugar levels. Pancreatic cancer usually starts in the cells that line the ducts of the pancreas. These cells are called pancreatic adenocarcinoma cells. Less commonly, pancreatic cancer can start in the hormone-producing cells or the enzyme-producing cells of the pancreas. Pancreatic cancer is a rare form of cancer, but it is one of the most deadly. The American Cancer Society estimates that approximately 56,770 people will be diagnosed with pancreatic cancer in 2018 and that approximately 45,750 people will die from the disease. There are several risk factors for pancreatic cancer, including smoking, obesity, diabetes, and family history. There is no sure way to prevent pancreatic cancer, but maintaining a healthy lifestyle may lower your risk. If you are diagnosed with pancreatic cancer, treatment options may include surgery, radiation therapy, chemotherapy, and targeted therapy. Clinical trials are also an option for some patients.

Did you know that pancreatic cancer is the fourth leading cause of cancer-related death in the United States? It's a terrible disease, and unfortunately, it is often diagnosed too late for effective treatment. But what if there was something you could do to reduce your risk of developing pancreatic cancer? Believe it or not, there may be! A recent Chinese study has shown a clear correlation between higher intake of vitamins and lower risk of pancreatic cancer. The researchers believe that the vitamins induce apoptosis in cancer cells, thus preventing them from growing and spreading. So if you're looking for ways to improve your health, start by adding some vitamins to your diet!

There are many different types of vitamins, and it can be confusing to know which ones you should take. However, the study's findings suggest that vitamin C, vitamin E, and beta-carotene are particularly effective in reducing the risk of pancreatic cancer. You can find these vitamins in many different foods, or you can take them in supplement form.

Getting more vitamins is just one part of a healthy lifestyle that can help reduce your risk of cancer. Eating a balanced diet and getting regular exercise are also important. And if you're looking for ways to improve your health, adding some vitamins to your diet is a great place to start!

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6390)


What is CBD?
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Date: May 15, 2019 01:54 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What is CBD?

Cannabidiol (CBD) is a cannabinoid

  • Cannabinoids are a class of chemical compounds found in cannabis plants
  • CBD is the most prominent cannabinoid found in Hemp
  • There are over 100 known cannabinoids found in the various cannabis species
  • CBD is NOT psychoactive & helps offset THC
  • Tetrahydrocannabinol (THC) is the psychotropic cannabinoid found in cannabis that makes you “high”
  • CBD has many health benefits
  • Clinical trials with CBD demonstrate improvements from issues including: anxiety, cognition, pain associated with exercise & movement disorders

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6322)


Drink matcha tea to enjoy these 6 health-boosting benefits
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Date: April 30, 2019 03:51 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Drink matcha tea to enjoy these 6 health-boosting benefits





Matcha is a powdered form of green tea derived from the Camelia sinensis plant and prized for its health benefits. Matcha is full of antioxidants and catechism that can help protect the health of your heart and arteries while keeping your cholesterol in check. Several clinical trials in both elderly people and the general population suggest that matcha can improve cognitive functioning. Matcha can also help you to lose weight by accelerating the rate at which your body burns calories.

Key Takeaways:

  • Although matcha tea is derived from,the same source as green tea, matcha tea is processed literally into a powder, which is what the name of the tea means.
  • Inflammation and oxidative stress, triggered by free radicals in the body, is significantly minimized by matcha tea, because it contains EGCG.
  • A 2014 University study used elderly participants to show that three months of regular consumption of matcha tea boosted the elderly participant's brain power.

"Matcha can even support a stable metabolism, keep the mind sharp and lift the mood, and purge toxins from the body."

Read more: https://www.naturalnews.com/2019-03-21-drink-matcha-tea-health-boosting-benefits.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=6220)


Garlic the master medicine: Scientists find a compound in the herbthat can destroy resistant bacteria
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Date: December 14, 2018 09:05 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Garlic the master medicine: Scientists find a compound in the herbthat can destroy resistant bacteria





Garlic is something that is present in many different types of foods on a regular basis. It is very interesting to see how many people like garlic and use it for different things. However, now garlic is being used for something a little bit more new. Within the herb, scientists have found really promising compounds that could help ruin bacteria. This is revolutionary for people who suffer from a lot of bacteria and the results are continuing to come in.

Key Takeaways:

  • There are a lot of doctors, and scientists, out there that are really starting to look more at natural substances for treatment.
  • Garlic is something that can be used for a lot of different reasons in the world today!
  • The more people who are tested with garlic being the medicine, the better the results can be when it comes to figuring out if it works or not.

"The researchers say that they believe their garlic drug could help treat patients whose outlook is otherwise poor. A biotech firm is developing the compound for use against bacterial infections, and human clinical trials are expected to be carried out soon."

Read more: https://www.naturalnews.com/2018-11-15-garlic-medicine-scientists-find-compound-destroy-resistant-bacteria.html

(https://vitanetonline.com:443/forums/Index.cfm?CFApp=1&Message_ID=5899)


CBD helps relieve anxiety without the high
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Date: June 07, 2018 05:16 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: CBD helps relieve anxiety without the high





CBD helps relieve anxiety without the high

CBD is being used in a variety of ways. One of the most popular is to treat drug addiction, which means it may be the key to ending the opiod crisis. CBD is being used to treat chronic illnesses as well as for pain management. It contains cannabindiol, but not the THC for the 'head high' but rather a 'body high' that relaxes muscles, relieves inflammation, and has even been credited with relieving gastrointestinal issues.

Key Takeaways:

  • Because cannabidiol (CBD) doesn't contain the psychoactive drug tetrahydrocannabinol (THC) it cannot make changes to the mind of the user.
  • Americans have adopted CBD widely, buying an estimated $100 million worth of CBD products although they do not have clear cut idea of its effects.
  • Dr. Blessing, a New York University (NYU) researcher, affirms that CBD does have an effect on the brain but this is in more medicinal ways.

"New York University (NYU) researcher Dr. Esther Blessing states that CBD shows potential as a means of treating addiction and anxiety. She adds that full clinical trials will be needed to determine its effects."

Read more: https://www.naturalnews.com/2018-06-04-cbd-helps-relieve-anxiety-without-high.html

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What Is CBD Oil Really Used For?
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Date: May 30, 2018 05:16 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: What Is CBD Oil Really Used For?





What Is CBD Oil Really Used For?

CBD is a non-psychoactive substance found in hemp and cannabis plants. CBD oil is the most commonly used form of cannabidol and the most widely studied. People use CBD oil for a range of health issues, including pain, addiction, and mental health problems. Others claim that CBD oil can decrease seizures, improve sleep, and reduce anxiety. More research on CBD oil is definitely needed to determine which conditions it can really help and what dosages are optimal. The American Academy of Pediatrics has issued a warning against CBD use in children due to concerns around healthy brain development.

Key Takeaways:

  • CBD may afford users relief from mental complaints, such as anxiety, comparable to the relief available from pharmaceutical treatments.
  • Clinical trials show that the oil may be a viable treatment modality for those suffering from addiction.
  • Those with difficulty sleeping may find relief with the use of CBD oil.

"CBD, or cannabidol, is one of the non-psychoactive components found in the cannabis or hemp plant."

Read more: https://www.huffingtonpost.com/entry/what-is-cbd-oil-used-for_us_5b044f27e4b003dc7e46fef1

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Is CBD Oil The Supplement That Your Workout Is Missing?
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Date: May 29, 2018 09:16 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Is CBD Oil The Supplement That Your Workout Is Missing?





Is CBD Oil The Supplement That Your Workout Is Missing?

Although hard evidence about the effects of cannabinoids like CBD is difficult to come by, our growing understanding of the body's natural endocannabinoid systems suggest that there is at least the potential for benefits from CBD for athletic performance. CBD, for example, may help boost the endocannabinoid system's suppression of pain and inflammation. However, it is also important to note that THC, the psychoactive ingredient in whole marijuana, appears to decrease long-range endurance. More research is sorely needed to understand just how CBD and other cannabinoid compounds impact athletic performance.

Key Takeaways:

  • A component called endocannabinoids is found in CBD oil which can help regulate brain function.
  • CBD oil is a more viable option for athletics as THC can really hinder levels of endurance.
  • CBD oil has not been proven to change a person's heart rate or blood pressure during physical activity yet.

"Despite anecdotal evidence that CBD oil might help with athletic performance and recovery, there actually haven't been any clinical trials examining those effects, says Brook Henry, PhD, an assistant research scientist at the University of California, San Diego's Center for Medical Cannabis Research and department of psychiatry."

Read more: https://www.refinery29.com/cbd-oil-for-exercise

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4 Groundbreaking Studies on Cannabis and Disease
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Date: November 17, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: 4 Groundbreaking Studies on Cannabis and Disease





Cannabis is becoming more popular for the treatment of many diseases and ailments. It is becoming legal in more places as well due to studies which show its effectiveness. This talks about four such studies. If you are leery of cannabis this might ease your mind. It is often helpful. Many people swear by it as a treatment. It also doesn't tend to have many negative side effects the way medications can. It is safer.

Key Takeaways:

  • Presently, 29 states and the District of Columbia have regulations in place that allow physicians to recommend medical cannabis to patients, however, dosage and treatment information is lacking.
  • There are currently four medical cannabis clinical trials happening in North America, which are assessing the benefits of medical cannabis on Alzheimer’s, Parkinson’s, PTSD, and brain tumors.
  • Hopefully, these new studies will help researchers and physicians determine exact doseages and treatment applications for specific ailments.

"This study will allow researchers to better understand the potential risks and benefits of cannabis use among veterans with PTSD and aid in cannabis-based decision making among patients and their physicians."

Read more: http://www.care2.com/greenliving/4-groundbreaking-studies-on-cannabis-and-disease.html

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Is CBD the Next Big Thing for Acne?
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Date: July 19, 2017 07:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Is CBD the Next Big Thing for Acne?





CBD may be the next big thing for acne. Synthetic cannabis has yielded some surprising results and it is a great way to treat acne. The phase 1 clinical trial has just been finished by a dermatological company. The goal of this drug is that one day it will be the answer for people struggling with acne. The clinical trials began last year in Australia. There is going to be a pilot program for acne patients later this quarter.

Read more: Is CBD the Next Big Thing for Acne?

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New Study to Explore Benefits of CBD for Veterans with PTSD
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Date: June 28, 2017 12:14 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: New Study to Explore Benefits of CBD for Veterans with PTSD





There is a Cannabidiol (CBD) study that involves veterans suffering from PTSD, and the effects that the CBD has on them and their trauma. The study is taking place in Florida, under the guidance of Wes Clark jr., a veteran who is passionate about assuring veterans that they can have safe access to cannabis. It is being funded by Alternative Health. Together they hope to bring easier access to CBD as well as sharing their findings with the medical community.

Key Takeaways:

  • There is a study being done to explore the use of CBD on veterans with PTSD.
  • The study will explore alternate delivery systems such as tablets that dissolve under the tongue and transdermal patches.
  • Clinical trials are necessary to change the thinking around using CBD in medicine.

"It is unquestionable that veterans receive comfort and relief from cannabis and CBD"

Read more: http://terpenesandtesting.com/new-study-explore-benefits-cbd-veterans-ptsd/

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Cannabis prevents brain aging
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Date: June 12, 2017 09:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cannabis prevents brain aging





Cannabis helps to prevent aging in people. Memory performance decreases with increasing age. Cannabis can reverse these aging processes in the brain. If given a low dose, it will help the elderly with their learning as well as their memory. Scientists have demonstrated this in a lab with mice. This is very exciting news and many people can benefit from this information. Researchers have been looking how to reverse the aging process for many years.

Key Takeaways:

  • Cannabinoids are naturally produced and perform important human brain functions
  • Loss of mental cognition is associated with nonfunctional cannabinoid receptors in the brain
  • Clinical trials may determine if chemicals in hashish and marijuana can aid recovery of cognitive abilities

"Low doses of the active ingredient in cannabis, THC, has the opposite effect on the elderly, reversing brain aging and restoring learning and memory."

Read more: https://www.healthnutnews.com/cannabis-prevents-brain-aging/

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Consuming silicon-rich water or foods can purge your body of up to 70% of the of aluminum in your bloodstream
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Date: April 08, 2017 11:44 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Consuming silicon-rich water or foods can purge your body of up to 70% of the of aluminum in your bloodstream





Despite the fact that aluminum is known to be a dangerous substance, it can be found in a large number of our regular items, for example, prepared sustenance, cookware, immunizations, prescriptions, child items, beauty care products, antiperspirants, sunscreens, cleaning items, tap water, and even noticeable all around we relax. The conclusion that drinking silicon-rich mineral water might be the answer for shield your body and mind from aluminum developments and cerebrum harm. Amid the clinical trials, including both solid people and individuals with Alzheimer illness, and found that drinking around one liter of silicon-rich mineral water each day can accelerate the discharge of aluminum by means of the kidneys and pee by up to 70 percent. Drinking silicon water is a non-intrusive approach to expel more aluminum from the body, something which benefits everybody, including immunized kids and individuals with infections, for example, Alzheimer's, dementia, and Parkinson's.

Key Takeaways:

  • Aluminum is stored in your body and causes many health problems including Alzheimer’s, Parkinson’s, multiple sclerosis (MS), and other neurological and autoimmune diseases.
  • Christopher Exley determined that people suffering from Alzheimer's who drink silicon-rich water show a cognitive improvement.
  • Silicon water increases the rate at which aluminum is removed from the body through the kidneys and urinary tract.

"Today, aluminum is so abundant in our surrounding environment that it is practically impossible to avoid. Therefore, Dr. Exley has dedicated over two decades of his life to researching the effects of aluminum toxicity."

Read more: http://www.naturalnews.com/2017-04-04-consuming-silicon-rich-water-or-herbs-can-purge-your-body-of-up-to-70-the-of-aluminum-in-your-bloodstream.html

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Watch ANOTHER Man with Severe Parkinson’s Take Cannabis Oil to Settle his Tremors
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Date: March 16, 2017 11:14 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Watch ANOTHER Man with Severe Parkinson’s Take Cannabis Oil to Settle his Tremors





In considering whether cannabinoids are a suitable therapy for Parkinson's symptoms, the potential benefits must be weighed against the possible side effects. Used in moderation, cannabinoids appear to be relatively well tolerated. Even so, a review of clinical trials involving cannabinoids showed that nearly seven percent of participants discontinued them due to issues such as nausea, dizziness, weakness, mood and behavioral changes, hallucinations and impairment of cognitive (memory/thinking) abilities.

[video mp4="//www.healthnutnews.com/watch-another-man-severe-parkinsons-take-cannabis-oil-settle-tremors/"]

Key Takeaways:

  • Marijuana has important medicinal benefits.
  • Marijuana is not harmful
  • Marijuana can help millions of people

"His used just a single drop and his hands afterwards were rock steady and the Dyskinesia left."

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Vitamin C effective in targeting cancer stem cells
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Date: March 12, 2017 03:59 PM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Vitamin C effective in targeting cancer stem cells





Cancer research has taken a front seat to many research projects over the years. Scientists have studied many different chemicals and how they can affect cancer cells. Vitamin C, which is an essential nutrient the body needs normally, has been found to be effective against some cancer cells in studies. Vitamin C has been shown before to be effective against cancer, but more research still needs to be done to show the best way to use this nutrient in therapy. Researchers want to use it to make chemotherapy and other drug options more effective.

Key Takeaways:

  • Vitamin C is up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2-DG, according to scientists in Salford, UK.
  • Vitamin C has previously been shown to be effective as a non-toxic anti-cancer agent in studies by Nobel Prize winner Linus Pauling and was recently shown to reduce mortality by 25% on breast cancer patients in Japan
  • "Our results indicate it is a promising agent for clinical trials, and a as an add-on to more conventional therapies, to prevent tumour recurrence, further disease progression and metastasis

""Vitamin C is cheap, natural, non-toxic and readily available so to have it as a potential weapon in the fight against cancer would be a significant step.""



Reference:

https://www.sciencedaily.com/releases/2017/03/170308083940.htm

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Cannabis and Epilepsy Treatment
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Date: January 30, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Cannabis and Epilepsy Treatment





For those who struggle with seizures or have a family member who does, it can be difficult to find a treatment plan that manages it effectively. CBD oil has become a promising choice for people in a situation where normal treatment options are not working. A lot of research is being done on the subject, but the advancement of the field is going slow. There are a few stories of CBD oil being used to prevent seizures in children who did not respond to more mainstream treatment. This has allowed them to be functioning members of society.

Key Takeaways:

  • Since medicinal cannabis has become a more commonplace alternative for a well-established list of ailments, patients are finding a place for it next to their Advil and Tums.
  • But unlike many other chronic illnesses that can be managed with over-the-counter supplements, epilepsy requires a specific cocktail of chemicals not readily available at the local corner store.
  • Cannabis has demonstrated so much promise in the treatment of epilepsy that FDA-approved clinical trials are underway.

"There has been no other drug in history that has been as widely consumed and applied for medicinal use without the institutional blessing symbolized by clinical human trials."



Reference:

https://www.google.com/url?rct=j&sa=t&url=https://www.leafly.com/news/health/marijuana-and-epilepsy-seizure-treatment&ct=ga&cd=CAIyGjViYjkzZDJlODZhNjI0ZWE6Y29tOmVuOlVT&usg=AFQjCNHdX4BW6YoxXcelYzaZ3r11N5gjgw

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Marijuana oil shows promise in treating epilepsy
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Date: January 12, 2017 07:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Marijuana oil shows promise in treating epilepsy





Recently a compound that is found in marijuana has been showing some great promise in regards to the treatment of epilepsy in both adults and children. After nearly two years of research, researchers are getting the data that they need to show that the treatment method works in general. Researchers observed a reduction in the number of seizures in the majority number of the patients during clinical trials in general.

Key Takeaways:

  • A compound found in marijuana is showing great promise in the treatment of epilepsy in both kids and adults.
  • After two years of research, "finally we are getting the data to show patients that the treatment works," explains UAB neurologist Dr. Jerzy Szaflarski.
  • They've observed a reduction in seizures in the majority of patients in clinical trials, and some are even seizure-free.

"Results are so promising with CBD that this marijuana derivative -- which can't make anyone high -- could be available to patients in need within 18 months."



Reference:

https://www.google.com/url?rct=j&sa=t&url=//www.wndu.com/content/news/Marijuana-oil-shows-promise-in-treating-epilepsy--408613585.html&ct=ga&cd=CAIyGmM2M2RhZjlmZTVmZDZjMmU6Y29tOmVuOlVT&usg=AFQjCNHXTm9wvPEMct6BPvUtc5_Ltou99w

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Protect yourself from flu season with these natural cold remedies
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Date: December 11, 2016 10:59 AM
Author: Darrell Miller (support@vitanetonline.com)
Subject: Protect yourself from flu season with these natural cold remedies





The common cold is an infection of your nose and throat caused by viruses. We typically catch between two and four colds a year. There is some evidence suggesting that people with higher levels of vitamin D may have a reduced risk of catching the common cold. Astragalus root has long been used in traditional Chinese medicine to strengthen immunity and prevent colds and flu. Studies have found that astragalus has antiviral properties and stimulates the immune system, although there have been no clinical trials examining the effectiveness of astragalus against colds in humans.

Key Takeaways:

  • Like clockwork, the cold and flu season is nearly upon once again. Cooler fall weather, kids heading back to school and other factors all contribute to the spread of influenza.
  • The fact is humans have used natural cold remedies to relieve symptoms of cold and flu since the earliest of times.
  • Also, a Zulu cold treatment that is made from the South African geranium Pelargonium sidoide is now a best-selling cold remedy the world over, because it, too, is supported by clinical research.

"For instance, elderberries have been used as medicine since the Stone Age, according to Melanie Grimes, scholar, academic, author and homeopathic expert."



Reference:

//www.naturalnews.com/056193_flu_season_natural_remedies_Big_Pharma.html

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Why Should We Take A Multi-Strain Probiotic?
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Date: September 01, 2015 08:19 PM
Author: Darrell Miller
Subject: Why Should We Take A Multi-Strain Probiotic?

Most people taking a probiotic supplement or drink do so for the purpose of supporting digestive health.  Probiotics increase the colonization of beneficial bacteria in the intestines and limit the proliferation of pathogenic or disease-causing bacteria.  A healthy intestinal microflora is believed to not only enhance digestion, but also promote general health and boost immunity.

Probiotics

Probiotics Offer More than Digestive Health Support

Probiotics offer medical advantages that go past the extent of supporting digestive wellbeing.  Recent studies demonstrate that particular strains of probiotics may be utilized to treat particular conditions.  Here's a rundown of advantages of taking probiotics supplement or drink:

  • An all around adjusted intestinal microflora may help direct solid cholesterol levels.
  • Probiotics, as a major aspect of a general solid eating routine, may help bolster safe framework and moderate diseases. Probiotics may fortify certain safe cells. This could help anticipate stomach and respiratory diseases in youngsters and also skin infections.
  • The utilization of probiotics in uro-vaginal diseases is very much bolstered by clinical trials and research.
  • Probiotics may be utilized to advance oral wellbeing averting tooth rot, especially in kids. In spite of the fact that this idea is moderately new, experimental backing shows probiotics treatment may hold a future in oral health.
  • Probiotics might likewise be recommended to treat conditions that have confounded traditional science, for example, Crohn's ailment, crabby inside disorder (IBS), lactose bigotry, certain sensitivities and skin infections.


Blend of Probiotics with Other Ingredients

Products that contain probiotics and a blend of different fixings are picking up prevalence since they offer more extensive advantages for wellbeing.


  • Probiotics with Prebiotics15

The symbiotic blend of probiotics with prebiotics multiplies the development of solid microflora. Prebiotics are insoluble fiber, for example, Fructooligosaccharides (FOS) and inulin, which achieve the colon in a genuinely undigested state. It is in the colon that probiotics feast upon prebiotics through a maturation prepare that happens in the colon. Amid this procedure, by-items called transient unsaturated fats (SFA) are delivered. SFAs help to keep up fundamental elements of the body and produce certain B vitamins.

  • Probiotics with Enzymes16

Probiotics can be consolidated with proteins that help separate sustenance substances into easier structures to improve supplement absorption. 

  • Probiotics with Multi-Vitamins17

Consolidating probiotics with a multi-vitamin is famous yet stances challenges in assembling because of the touchy way of probiotics. Probiotics are delicate to light, dampness, heat, oxygen.


How Probiotics Manufacturers Can Provide Retailers with Reliable Probiotics Supplements

The greatest test that probiotics producers face is keeping the microorganisms alive amid the mixing procedure while guaranteeing strength amid timeframe of realistic usability.  At the point when joined with different fixings that are similarly touchy, for example, proteins, compelling consideration ought to be taken to guarantee that the assembling and bundling procedure happen in a dry situation. Any dampness may initiate the proteins and wreck the probiotics.


Microencapsulation

Microencapsulation is a genuinely late innovation that guarantees the survival of probiotics amid surrounding so as to assemble and stockpiling it with an external covering. Microencapsulating shields probiotics from ecological defilement and forestalls unplanned blending of probiotics with different fixings in the recipe that may bargain its solidness.


Guaranteeing the Right Strain and Count

The wellbeing presenting advantages of probiotics are strain-particular. Diverse strains have particular capacities in the body and not all strains are valuable to wellbeing. Probiotic formulators must be knowledgeable in probiotic strains and the utilization of proper strains for the sought condition-particular capacities. Slight variety in the hereditary profile of strains could create undesirable results.


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Homeopathic Remedies
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Date: June 30, 2014 09:54 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Homeopathic Remedies

Homeopathic remedies

The utilization of homeopathic remedies is an option to tried and true therapeutic medicine. A moderately new limb of solution, it utilizes a comprehensive methodology for treating side effects of a condition. Homeopathic remedies are developing in prominence, generally on the grounds that tried and true therapeutic medicine has been frequently unsuccessful the root issue of a condition, not simply side effects.

Homeopathy- -the act of homeopathic drug -was initially utilized by Dr. Samuel Hahnemann in Germany in the eighteenth century. It utilizes the antiquated idea of "like cures like," an idea that is much the same as that of inoculation. Its reason is that if a substantial amount of a substance causes, manifestations in a sound individual, then a little measure of that same substance will cure an individual experiencing those indications.

Speculations

The speculations about exactly how homeopathic remedies function are backed by real clinical trials and in practice. Professionals who use homeopathic remedies accept that that the human body is always striving to achieve a state of regularity. It responds to transform it deciphers as "fixable." Homeopathic remedies work by utilizing a little weakened measure of a substance to fortify the body's recuperating systems. The conviction is that this will trigger the invulnerable framework to assault the illness and the body will come back to an ordinary, sound condition.

Methodology

Homeopathic meds are accessible over the counter, however an assessment by a confirmed homeopathy specialist is prescribed before curing toward oneself. Throughout a homeopathic assessment, side effects of an infection are deliberately watched and reported, alongside insights about the general conduct of the patient. Insights about the persistent's preferences and aversions, general demeanor and identity characteristics are contemplated. A homeopath utilizes these perceptions to guide the patient in picking the best cure and dose for his specific condition.

Contemplations

There is no genuine experimental confirmation that medication with homeopathic remedies is powerful. On the other hand, the therapeutic group recognizes that it is conceivable that some of these remedies may be useful and it is for the most part concurred that they are totally protected. Homeopathy is still an extremely youthful extension of the drug. Extra experimental study is required to keep in mind the end goal to accommodate clashing convictions concerning its adequacy.

Why use Homeopathics?

Homeopathy is the second most broadly utilized arrangement of pharmaceutical as a part of the world. Its development in ubiquity in the United States has been around 25 to 50 percent a year all through the most recent decade.

This achievement is powered by a few elements:

• Homeopathy is greatly powerful. At the point when the right cure is taken, results might be fast, finish and lasting.

• Homeopathy is totally protected. Indeed infants and pregnant ladies can utilize Homeopathy without the risk of symptoms. Homeopathic remedies can likewise be taken nearby other pharmaceutical without delivering unwanted reactions.

• Homeopathy is common. Homeopathic remedies are ordinarily focused around characteristic fixings.

• Homeopathy works in concordance with your insusceptible framework, dissimilar to some customary meds which stifle the invulnerable framework.

• Homeopathic remedies are not addictive - once alleviation is felt, you ought to quit taking them. On the off chance that no alleviation is felt, you are likely taking the wrong homeopathic cure.

• Homeopathy is comprehensive. It treats all the side effects as one, which in reasonable terms implies that it addresses the reason, not the indications. This frequently implies that side effects handled with Homeopathy don't repeat.

• Homeopathic remedies are sheltered items that create no reactions. The doses are so little and weakened that they are totally safe. Additionally, some feel that the significant serenity connected with utilizing regular substances helps a general feeling of prosperity that helps help the resistant framework and empowers the body to heal itself.

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Is Coconut Oil A Brain Food?
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Date: January 26, 2014 09:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is Coconut Oil A Brain Food?

It is amazing how coconut oil has been ascribed as a good brain food.

coconut treeSince Dr. Mary Newport associated coconut oil with the ability to cure Alzheimer’s disease, it has attracted the attention of researchers and other interested parties. However, her attractive explanation of how the oil helped her husband to improve her husband’s Alzheimer’s disease can be described from the observation of an Alzheimer patient’s brain.

Taking into consideration Axona that is usually used by Alzheimer’s patients, its active ingredients is the caprylic acid that is extracted from the oil. As a substitute, Dr. Newport used coconut food products such as oil and milk in her husband diet to achieve the same quantity of MCTs. This improved her husband’s condition a clear indication that coconut oil has some medicinal value. From a scientific point of view, it is approved that the disease is caused by insulin resistant cells thus causing the brain to unsuccessfully use glucose to fuel their activity. In its place, ketone bodies are used as a substitute fuel supply. Coconut oil is a good supply of medium-chain triglycerides (MCTs), for instance caprylic acid that is simply transformed into ketone bodies in the liver when ingested. Then they act as an alternative of glucose which provides fuel for the brain. Neuroprotective effect of the coconut oil is attributed to the ketone bodies formed as a byproduct of coconut oil metabolism. Therefore, leading to an energy metabolism. The ketone bodies will then supply the compromised brain structure with the much-needed alternative fuel source from the Ketone bodies.

However, it is of the essence to state that coconut oil is only known for improving the condition. For this reason, there has been an increased call for more research, particularly human clinical trials. Since there is no any cure yet, coconut oil is going to remain a good brain food of choice for others who are experiencing Alzheimer.

References:

  1. //www.greenmedinfo.com
  2. //www.naturalnew.com/030373_cocnut_oil_alzheimers_disease.html
  3. //www.naturalnews.com/028753_alzheimers_drugs_trials.html


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Impacts of pantethine
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Date: January 09, 2014 04:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Impacts of pantethine

What is Pantethine

vitamin b5Pantethine (bis-pantethine or co-chemical pantethine) is a dimeric type of pantothenic harsh corrosive (vitamin B5). It is made out of two particles of pantothenic harsh corrosive connected by cysteamine crossing over aggregations. The monomer of this compound is regarded as pantetheine and is a halfway in the generation of Coenzyme A by the form. Pantethine is acknowledged the all the more naturally animated type of vitamin B5, yet it is less stable, disintegrating over the long haul in the event that it is not kept refrigerated most vitamins B5 supplements are subsequently as calcium pantothenate, a salt of pantothenic harsh corrosive.

Dietary supplementation

Pantethine is accessible as a dietary supplement due to proof of its health profits. In different clinical trials of patients with hoisted cholesterol and triglycerides, absolute and LDL cholesterol were diminished by 12%, triglycerides diminished by 18%, and HDL cholesterol was expanded by 9%. These clinical trials were directed with day by day admissions running from 600 to 1200 mg/day. Inside this measurement go there is no proof of a measurements impact relationship, i.e. changes in lipid focuses covered over the reach of measurements. Immediate measurements reaction proof is not accessible in light of the fact that no trial tried more than one measurement. A couple of trials tried 300 mg/day with additional unobtrusive yet factually noteworthy effects.

Further deliberately regulated trials of 600 and 900 mg/d dosages have indicated factually huge bringing down of LDL cholesterol in people with extraordinarily or reasonably raised levels of blood lipids.

Physiological impacts

Two instruments of activity are proposed for pantethine. In the in the first place, pantethine serves as the forerunner for amalgamation of coenzyme A. In the second, pantethine is changed over to two pantetheine particles which are thusly metabolized to structure two pantethenic harsh corrosive and two cysteamine atoms. Cysteamine is conjectured to tie to and therefore inactivate sulfur-holding amino acids in liver catalysts included in the generation of cholesterol and triglycerides.

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How Does Tart Cherry Fight Gout?
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Date: November 01, 2013 07:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Tart Cherry Fight Gout?

 Tart cherry studies

tart cherryThe problem whether tart cherry is helpful for gout sufferers or not has been intensely discussed during the past few years and after several studies and clinical trials, the researchers discovered that taking tart cherry extract or juice represents an effective solution to treat this health issue and ease its symptoms.

What can tart cherry do

How can tart cherry be helpful in case of gout sufferers? In the first place, cherries have always been used in traditional medicine for promoting normal levels of uric acid within the blood – given that high blood concentrations of this heterocyclic compound lead to gout, modulating them using cherries will automatically prevent this affection from occurring and reduce the pain and swelling it causes.

As mentioned above, there have been various studies targeting the effect of tart cherry on gout and according to the most recent one, consuming approximately 280 grams of cherries will decrease the uric acid levels with approximately 14% and increase the excretion of uric acid at the same time. Whether it is about regular tart cherry juice or medication, the effect will be mostly the same, reducing the pain caused by gout substantially.

What tart cherry contains

It should be noted that tart cherries contain approximately 10 milligrams of vitamin C in their composition, an organic (carbon-based) compound that can successfully ameliorate the inflammation and swelling produced by the gout and promote the uric acid excretion. Vitamin C acts primarily as an antioxidant, determining the human organism to eliminate not only the toxins from the tissues, but also the uric acid crystals that deposit in joints, tissues or tendons.

Whether we talk about tart cherry juice or supplements, this natural solution does not involve any potential health risk for gout sufferers, lowering the erythrocyte sedimentation rate (which is an indicator of chronic inflammation) significantly and helping the blood stabilize the normal uric acid levels.

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How Does Creatine Boost Muscle Strength?
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Date: October 28, 2013 11:13 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Creatine Boost Muscle Strength?

 

How Does Creatine Boost Muscle Strength?


meat proteinFirst of all what is Creatine? Creatine is a protein that is produced by the human body and converted to creatine phosphate and stored in muscles. The stored form can then be utilized for energy by the muscles. It is also found in meat and protein rich food products such as fish. Some clinical studies have surmised that creatine as an oral supplement enhance muscle strength and increase lean muscle bulk.


What Creatine Can Do?


Many young athletes utilize creatine supplements as part of their muscle building routines. Although there have been varied responses to these diet supplements creatine continues to thrive on the market as a sports and health vitamin. Other uses of it include lowering triglycerides in the body as well as homocysteine both of which play a role in heart attacks and strokes. Creatine also promotes better endurance and muscle strength among patients with chronic obstructive pulmonary disease, Parkinson's disease and Muscular Dystrophy. Clinical trials are still under way.

Creatine, like all other medications and supplements may cause some adverse effects. It is important that you consult a health service provider or pharmacist before initiating the use of the supplement. The common side effects of Creatine include muscle cramps, weight gain, muscle strain, abdominal discomfort, changes in bowel movements, dizziness as well as liver and kidney dysfunction. This is due to the fact that this protein is metabolized in the liver and the kidney.


Taking Creatine


Creatine should be taken in the recommended dose. Taking more than the recommended dosage can result to severe adverse events such as Rhabdomyolysis which is the medical term for the breakdown of muscles, the components released after massive muscle cell death can damage the kidney and lead to kidney failure. The recommended dose for adults is 2g daily. Using creatine for prolonged periods may eventually lower your body's production of creatine and may lessen its effects.

When used judiciously and properly you can benefit from the positive effects of Creatine.

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How Does Phosphatidyl Serine Improve Your Health?
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Date: April 17, 2012 07:22 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Phosphatidyl Serine Improve Your Health?

Health Benefits Of Phosphatidyl Serine

Phosphatidyl serine is phospholipid that is vital to your brain functioning. The phospholipid are molecules containing both fatty acids and amino acids found in every cell in the body. Phodphatidyl Serine supplements are plant extracts that has been proven safe and effective therapeutic substance in remedying memory disorders as well as in enhancing higher brain functions. Clinical trials have shown that this vitamin supplement do strengthen your memory, increase mental acuity, increase concentration, boosts learning, enhances attention and vigilance. In addition, Phodphatidyl serine relieves depression while improving your mood and inhibits increases in cortisol induced by exercise and stress.

The supplement works by enabling your brain cells to metabolize glucose and releases it to bind with neurotransmitters which hence support learning, memory and other cognitive functions. Phodphatidyl serine enhances the cells communication in the brain through increasing the number of membrane receptor sites. It is also important to note that this natural supplement modulates the fluidity of the cell membranes which are essential in supporting the ability of brain cells to send and receive chemical communications.

Health Benefits

Another health benefit associated with Phodphatidyl serine is its ability to restore the supply and output of acetylcholine in the brain. Acetylcholine is an essential transmitter to memory and is associated in reversing aging. Further, it increases the availability of endogenous chlorine used for de novo synthesis and production. Patients diagnosed with clinical depression that have ben put under the treatment of Phodphatidyl serine have registered a remarkable improvement with their symptoms. This follows from the fact that the supplement stimulates the production of dopamine by the brain. A deficit in dopamine in the brain has also been associated with attention deficit disorder and hence the natural supplement of Phodphatidyl serine has demonstrated to be an effective remedy for the disorder.

Weight Training

Research indicates that athletes involved in weight training, endurance running and cycling can reduce muscle soreness when they use Phodphatidyl serine. The athletes on this supplement have also been reported to undergo speed recovery during their rigorous training sessions. Other benefits of the supplement include; testicular function, formation of bone matrix, heart beat coordination, cell repair and removal by the immune system and secretion of hormones by the adrenal glands.

Stress

It is vital to note that phodphatidyl serine is present in almost every cell in our body and the membrane proteins it activates are important in all these cells. However, our bodies cannot produce enough amounts of it when under stress, when there is a deficit in necessary enzymes and metabolic cofactors, and when aged. Stress increases the demands for phospatidylserine thus depleting the available levels in the cells. On the other hand, aging not only increases the brain's requirement for phosphatidylserine but also leads to inefficiency in the digestive and metabolic functions of the body. This makes it difficult for aged people to acquire enough of it from the diet and thus it is recommended that aged people should use phosphatidyl serine supplements.

Modern diets with low fat and low cholesterol levels have been shown to be lacking in phodphotidyl serine to levels of up to 150 mg per day. A vegetarian diet on the other hand may have a deficit of up to 250 mg per day. This deficit in supply of Phodphatidyl serine in the diet leads to impairment of your brain's ability to form, store, process and even remember. It is vital hence to consider taking vitamin supplements with phosphatidyl serine to cater for the deficit which may be detrimental to your health.

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What is Fenugreek Seed and How Does It Boost Your Health?
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Date: July 07, 2011 11:16 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Fenugreek Seed and How Does It Boost Your Health?

Fenugreek seed and your health

Fenugreek seed is a spice often added to curries and other Indian dishes. It is a good source of protein and nutrients. In folk medicine, it has been used in the treatment of pain and irritation characteristic of inflammation. It is historically utilized to promote lactation. More recent studies have shown that it displays antiviral properties. In particular, it has been tested in allaying symptoms of cold infections.

Trigonella foenum-graecum is a plant species that belongs to the legume family. As such, it has been cultivated as a vegetable even before the ancient times. It is believed to be an indigenous species of the Fertile Crescent, a historic region that comprises the modern countries Israel, Lebanon, Jordan, Iraq, and Syria. To this day, it remains an important crop, herb, and food source in these countries.

Combats Diabetes Mellitus

Fenugreek seed has been the subject of scientific research in the past few years. Drawing on its use in traditional medicine, it has been employed in the management of blood sugar. It improves the effect of the hormone insulin in regulating glucose levels. In fact, it has shown great potential in treating both type I insulin dependent diabetes mellitus and type II noninsulin dependent diabetes mellitus.

Alters Blood Lipid Profile

The phytochemical content of fenugreek seed enables it to effectively lower cholesterol levels in the blood. Clinical trials have recorded changes in lipids present in the systemic circulation after intake of fenugreek seed products. It is now postulated that it blocks the metabolic pathway for the synthesis of low density lipoproteins or bad cholesterol. Some sources say that it raises good cholesterol levels.

Solaray - Fenugreek Seeds 180ct 620mgIncreases Milk Production

Fenugreek seed is rich in organic compounds that promote the secretion of milk products within the mammary glands of lactating women by as much as 900 per cent. Traditionally, the seeds are ground into powder and consumed in large quantities by pregnant women. Today they are made into capsules, which have been reported to display the same benefits and remain popular in the Indian subcontinent.

Relieves Viral Infections

There is a growing body of literature devoted to the putative antiviral properties of fenugreek seed. A number of researchers have attested that the seed displays biochemical activity that interferes with the replication of viruses. For instance, topical applications of fenugreek extracts have shown desirable results in removing viral skin conditions, and oral intake has been effective in easing the common cold.

Promotes Skin Health

Fenugreek seed is a natural conditioner and moisturizer. It promotes retention of moisture in the skin and protects the outer layer of the skin from irritants. It has been used as salves to wounds, rashes, boils, bruises, allergies, and insect bites. It is made into a syrupy mixture that is directly applied to the hair. It regulates the production of sebum in the hair follicles and helps control dandruff.

Solaray - Sunny Greens - Thompson nutritional - Veg Life Vegan Line - Premier One - NaturalMax - Kal

Grab some fenugreek seed and feel the difference!

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What is the Difference between Echinacea angustifolia and Echinacea purpurea?
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Date: July 06, 2011 10:32 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is the Difference between Echinacea angustifolia and Echinacea purpurea?

Echinacea Health Benefits

Echinacea is a group of plant species that belongs to the same family as dandelion, sunflower, and daisy. These flowering shrubs are best known as ornamental plants in gardens. Also, they are widely recognized as medicinal herbs in alternative medicine. Modern herbalists have attributed a diverse variety of healing properties to this herb, drawing on its traditional uses among the Native Americans.

Echinacea angustifolia

Elk root, black samson echinacea, or narrow-leaved purple cornflower refers to Echinacea angustifolia. Its native range stretches from Manitoba in the north to Texas in the south. It is an herbaceous plant, as all species of echinacea are. It grows up to 28 inches in height, extending from a branched taproot. Its stems and leaves are hairy while other species are smooth. Its flowers resemble a cone in shape.

Echinacea angustifolia is so named in the vernacular due to the fact that elks knowingly consume the plant when sick or wounded. Elk root is an herb important to folk medicine practices of Plain Indians, such as the Cheyenne and Apache. It displays analgesic properties, and thus has been in use as a pain reliever for external wounds and internal inflammation, including allergies, rheumatism, and arthritis.

Research on elk root has been promising. It is one of the species of echinacea believed to enhance the immune system and improve immune responses. In particular, it is good for the respiratory system. It has been used in the treatment of the common cold, sore throat, and nasal congestion. In addition, it exhibits antimicrobial properties, which effectively wards off infections of the respiratory tract.

Echinacea purpurea

Eastern purple cornflower, or simply purple cornflower, refers to Echinacea purpurea. It enjoys a wide distribution in North America, though they thrive in large concentrations in the wild in regions close to the east coast. Unlike all other species of echinacea, it grows from a woody base with fibrous roots instead of a taproot. Its flowers are arranged in a cone, sitting atop a stem that grows up to 40 inches.

Echinacea purpurea is arguably the most extensively studied of all species of echinacea. Traditionally, it has been utilized by many different tribes in North America as a cure-all medicinal herb. Clinical trials have shown that juice extracts obtained from this plant species are useful for the short term treatment of cold infections, though contraindications in children and pregnant women were noted.

Echinacea purpurea displays chemopreventive potential. Laboratory studies have discovered that it contains alkamides, which bind to cannabinoid receptors and inhibit tumor growth and pain chemicals in the process. Also, it has been linked to immunotherapy largely owing to its properties that appear to increase the activity of immune cells. It shows promise as an adjunct treatment for cancer.

Either way, Echinacea can help boost the body so the body can fight back against disease. Make sure you have some in your medicine cabinet just in case you feel a cold coming on!

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Does Boron Really Help Improve Bone Health?
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Date: July 01, 2011 11:06 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Does Boron Really Help Improve Bone Health?

Boron and Bone Health

Boron is now widely considered an essential mineral, though its daily value is still a matter of debate. The physiological roles of this chemical element in the human body were unknown in the first half of the 20th century, but in recent years scientific research has proven that it is necessary for the calcium metabolism and vitamin D utilization, both of which significantly contribute to overall bone health.

There has not been any figure set in the dietary reference intake for boron largely owing to the fact that its nutritional importance has not been discovered until recently. As a result, important data on the safety of boron intake as a dietary mineral remains under investigation. Nonetheless, the scientific community is convinced that the presence of boron is required for many different metabolic processes.

Plants need relatively higher amounts of boron to survive. It follows that plant-based foods are very good sources of dietary boron whereas animal products have negligible amounts of this element. This chemical element was first noted to have a positive effect on joint health. The studies that followed have been observed that boron supplements alleviate symptoms of osteoarthritis in human trials.

Promotes Bone Health

Concentrations of boron in the synovial fluid and joint cartilage help determine the health of joints and bones. It has been reported that people who have higher amounts of elemental boron rarely develops degenerative joints diseases like osteoarthritis and symptoms of joint pain. Also, epidemiologic studies have shown that populations noted for healthy consumptions of boron have lower incidence of arthritis.

More recent studies have shown that boron intake is directly proportional to bone density. For one, it has been documented that supplementation of boron has an impact on bone strength in patients with osteoporosis. Clinical trials have produced very promising results as far as the treatment of bone loss is concerned. There is very good scientific evidence that boron supplements are superior to placebo.

Inhibits Bone Resorption

The skeletal system is the primary depot for minerals in the human body. Chemical elements obtained from the diet are stored in the bones or otherwise utilized by tissues and organs. In particular, more than half of the overall body concentrations of calcium, potassium, and magnesium are found in the bones, which are constantly remodeled to draw minerals out in response to the needs of body tissues.

The process of bone resorption is responsible for releasing the minerals from the bones into the blood. On the other hand, the process of bone resorption takes care of building bone tissue. If consumptions of dietary minerals are insufficient, resorption exceeds formation, as is the case with osteoporosis. The presence of boron promotes mineral retention in the bones, thereby increasing bone mass and density.

If you are experiencing osteoporosis, give boron a try!

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Can Dietary Collagen Help the Skin and Joint Tissue?
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Date: June 30, 2011 10:45 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Can Dietary Collagen Help the Skin and Joint Tissue?

Collagen and Your Health

Collagen is the most common form of protein in humans and other mammals. It is a major constituent of the extracellular matrix that provides structural support to animal cells from the outside. It displays great tensile properties, which is responsible for the strength and elasticity of the skin. Since it is a component of fibrous tissue, it is also found in ligaments and cartilages that make up joint tissue.

Dietary collagen has long been postulated to contribute to the biochemical composition of cells present in the skin and joints. Proponents of collagen supplements believe that dietary collagen is assimilated into the extracellular matrix and fibrous tissue. The scientific community has been doubtful about the efficacy of topical applications of collagen, but oral supplements have been promising in clinical trials.

Molecular collagen is composed of polymers of amino acids linked by peptide bands, which are too big at the cellular level to get absorbed through skin. On the other hand, intestinal absorption of dietary collagen remains a matter of controversy. That being said, nutraceutical companies have developed formulations of supplements that facilitate the best possible absorption rates and better bioavailability.

Tough bundles of collagen fibers comprise several polypeptide chains of fibrous structural proteins. All fibrous tissues have cells and extracellular matrix in between. High concentrations of collagen found in cartilages, ligaments, tendons, fascia, and even bones give these fibrous tissues tensile strength, the reason why the joints are capable of bearing a certain level of longitudinal stress without tearing apart.

Structural proteins make up the outer layer of the human skin and its appendages, such as the scalp, hair, and nails. The most important of these proteins are collagen, keratin, and elastin. Collagen fibers are responsible for the tensile properties of the skin. Keratin provides strength whereas elastin exerts an elastic effect. Collagen fibers affect the process of healing and its degradation leads to wrinkles.

Oral route of administration is believed to produce the health benefits linked to dietary collagen. While researchers have ruled out the health claims tied to collagen creams and lotions, they have reported encouraging results about dietary collagen. In fact, collagen supplements utilized in the management of rheumatoid arthritis and treatment of skin disorders have produced significantly positive outcomes.

One clinical trial that involved more than 200 participants diagnosed with rheumatoid arthritis point to the medicinal potential of collagen as an adjunct treatment for rheumatism and osteoarthritis. There was a noticeable decrease in joint pain, morning stiffness, and restrained mobility, which were noted as statistically significant. For this reason, supplementation of collagen has attracted more research.

Dietary collagen is now becoming increasingly visible in the nutraceutical industry in that sales have increased in the past few years. It has become the subject of numerous studies well underway, and as such developments in collagen supplementation are expected to produce formulations specialized for higher bioavailability. The good news is dietary collagen has not been linked to any adverse effects.

Get some collagen today and feel the difference it can make in your diet!

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What Makes a Good Joint Complex or Formula?
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Date: June 29, 2011 11:44 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What Makes a Good Joint Complex or Formula?

Glucosamine/Chondroitin/MSM

Joint pain is a common medical condition that afflicts billions of people worldwide. It is brought on by many different factors, though most of the cases have been tied to arthritis. The joints are especially susceptible to inflammation in old age partly due to the fact that cartilage health becomes impaired as we age. The good news is that certain organic compounds replenish the cartilage content of joints.

Medications and remedies formulated to alleviate joint pain have been extensively studied in the past few decades. Analgesics remain the mainstay of treatment for arthritis to this day, but alternative medicine has also made advances. Proponents of nutritional supplements believe that a good joint formula does not only provide relief from pain but also supplies the proteins necessary for joint health.

Glucosamine

Joint cartilage comprises a group of complex carbohydrates called polysaccharides or oligosaccharides that are attached to proteins. In a process called glycosylation, enzymes add long unbranched chains of carbohydrates to core proteins and form proteoglycans, which nourish the extracellular matrix found in cartilages. In the case of osteoarthritis, the proteoglycan content of joints dwindle with age.

Glucosamine is a precursor to polysaccharides and oligosaccharides. In particular, it is utilized by enzymes to form glycosaminoglycans, which are in turn added to proteoglycans. As a treatment for joint pain, it comes in the form of glucosamine sulfate and glucosamine hydrochloride. It is one of the most promising of all complementary therapies for arthritis as studies have reported positive results.

Chondroitin

Therapeutic remedies that contain glucosamine often come with chondroitin. The sulfated form of chondroitin is a major constituent of proteoglycans, and as such it is generally found in large amounts in joint cartilage in humans. For decades, chondroitin has been used as a therapeutic remedy for arthritis in conjunction with glucosamine as they are believed to enhance the efficacy of each other.

Proponents believe that chondroitin and glucosamine supply the body with healthy quantities of glycosaminoglycans for use by enzymes in the synthesis of proteoglycans. There is consensus in the scientific community that its long term use for the sole purpose of treating osteoarthritis is safe. In addition, recent studies and clinical trials in the past few years have been very encouraging.

MSM

Methylsulfonylmethane, often abbreviated as MSM, is a compound listen as an ingredient in joint formulas. Nutraceutical experts believe that the best joint formula currently available contains all three: glucosamine, chondroitin, and methylsulfonylmethane. While glucosamine and chondroitin provides nutrition for cartilage tissue, MSM counteracts inflammatory mediators that cause joint pain.

Alternative remedies have been the subject of most studies on arthritis in recent years. While analgesics remain commonly used, dietary supplements are becoming increasingly popular among people suffering from joint pain. Glucosamine, chondroitin, and MSM are the most studied of all supplements formulated for joint pain, the reason why health care providers recommend them first.

Grab yourself a joint formula complex and feel the difference!

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Boost Brain Chemistry, Lower Bad Cholesterol, And More
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Date: May 12, 2011 01:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Boost Brain Chemistry, Lower Bad Cholesterol, And More

What is Inositol Good for?

Inositol is an organic compound present in many plant-based foods. Popular nutritional sources of inositol include brown rice, wheat bran, whole grains, beans, nuts, and other foods rich in fiber. It is a polyphosphorylated carbohydrate that was once classified as an essential nutrient together with B-complex group of vitamins. It is an important component of signal transduction of cells, amplifying the strength of signals from the receptors on the cell surface to target molecules within the cytoplasm.

Cancer research on inositol is one of the most publicized. Fruits and vegetables that are known for their high fiber content also contain large amounts of inositol, which is believed to prevent the inactivation of DNA repair gene and protect the cells from mutation that lead to carcinogenesis. In laboratory studies it has shown great medicinal potential as a therapeutic remedy for various cancers. In addition, it has been extensively utilized in the treatment of psychiatric disorders.

Rebalances Brain Chemicals

Supplementation of high dose inositol has been observed to be beneficial to sufferers of mental illnesses. There have been numerous clinical trials focused on its effects on the chemical compounds found in the central nervous system, and early studies recorded that its mechanisms of action are similar to a class of antidepressants called selective serotonin reuptake inhibitors, or SSRIs.

A growing body of scientific literature is devoted to its purported role in the amelioration of anxiety disorder, panic disorder, obsessive-compulsive disorder, clinical depression, and bipolar disorder. It has been favored over some SSRIs because of its desirable results and absence of side effects. It has particularly benefited individuals diagnosed with obsessive compulsive disorder, with testimonies being largely positive. Also, it has been reported to also reduce frequency of panic attacks.

Lowers Bad Cholesterol

High-fiber diet has always been recommended to manage high cholesterol levels. It emphasizes the intake of whole grains, fruits, and vegetables. The same group of foods is rich in the carbohydrate inositol. In the latter half of the 20th century, it was discovered that inositol in fact contributes to the breakdown of fatty molecules, such as triglycerides, in the gastrointestinal tract and interferes with their absorption. More importantly, regular consumptions of inositol appear to reduce overall lipid levels in the blood. It is postulated that it blocks the metabolic pathway that integrates triglycerides in very-low-density lipoproteins, the immediate precursors of low-density lipoproteins, also known as bad cholesterol. By so doing, it not only lowers cholesterol and free fatty acids found in systemic circulation but also prevents cardiovascular diseases, such as atherosclerosis.

Other Benefits

Many nutraceutical products that contain inositol are commercially touted to aid weight loss. Inositol has also been associated with the alleviation of digestive problems, most notably constipation. It is believed to soften the stool by attracting water as it works its way into the alimentary canal, and regular intake promotes regularity. Furthermore, it has been linked to hair growth as low levels of inositol have often been tied to hair loss.

Taking a inositol supplement can help you obtain all the inositol you need for your daily needs!

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How Does Nattokinase Help Improve Cardiovascular Health
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Date: April 29, 2011 04:01 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: How Does Nattokinase Help Improve Cardiovascular Health

Nattokinase And Your Health

Nattokinase is an organic compound that occurs naturally in the Japanese food natto, or fermented soybeans. It is an enzyme that acts on fibrous proteins responsible for blood clothing, and as such has been commercially touted to work like thrombolytic medications to a certain degree. Its synthesis involves fermentation that results from adding the bacterium Bacillus subtilis to boiled soybeans.

Natto is a traditional dish in Japan. It has enjoyed long-standing popularity among the Japanese people since feudal times largely owing to its reinvigorating effects on the blood. In recent years, laboratory studies point to the presence of chemical compounds in fermented soybeans. The enzyme nattokinase appears to be the active ingredient, improving fibrinolytic activities in animal subjects.

Breaks Down Blood Proteins

Proteases are enzymes capable of reducing proteins into smaller peptide chains in the digestive system or anywhere in the body. A special kind of protease called plasmin is found in the blood. It is the primary enzyme that facilitates the catabolism of fibrin clot, or coagulated blood protein. Fibrinolysis is the process initiated by the enzyme plasmin to dissolve compacted red blood cells.

Thrombolytic drugs work on the principle of raising the levels of plasmin in the blood. Streptokinase is one of these drugs. It is commonly administered in the treatment of myocardial infarction, or heart attack to avoid complications. Natto has been compared to streptokinase, and oral intake of nattokinase has been observed to stimulate productions of plasmin.

Prevents Blood Coagulation

Nattokinase has been extensively studied in Japan, though well designed large-scale randomized clinical trials are still needed to establish its purported benefits to human health. There is buzz around nattokinase in the pharmaceutical industry especially as early studies suggested that it may ameliorate complications of cardiovascular diseases, notably in the removal of platelet-fibrin emboli.

There have been numerous citations on the blood-thinning capacity of nattokinase. This enzyme is also believed to have an inhibitory effect on platelet aggregation. Thrombocytes, or platelets, are necessary for containing excessive bleeding. However, aggregation of platelets may result in thrombosis in patients with history of atherosclerosis and other disorders of the blood vessels. Nattokinase is a blood thinner that affects both platelets and fibrins.

Improves Cardiovascular Health

In addition to its thrombolytic and anticoagulant properties, nattokinase has been reported to promote normal flow of blood. Natto has been linked to the alleviation of high blood pressure and has seen desirable outcomes in hypertensive patients. Recent studies have shown that nattokinase is responsible for producing antihypertensive and vasodilator effects when natto enters the systemic circulation. It is postulated that nattokinase inhibits angiotensin-induced vasoconstriction.

The Japanese have always believed that natto is good for the blood. Nattokinase remains under scrutiny, but clinical trials are well underway. A growing body of literature devoted on promoting its alleged health benefits draws so much on decades-long anecdotal evidence.

If you want to improve cardiovascular health, give Nattokinase a try!

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Why is Maca Called the Peruvian Ginseng and What Does this Herb Do
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Date: April 28, 2011 03:17 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Why is Maca Called the Peruvian Ginseng and What Does this Herb Do

Maca: Stress, Energy, Libido, and More.

Maca is a root vegetable traditionally grown at high altitudes in Peru. It is related to radish and turnip, both of which it resembles in appearance, size, and proportion. Its historical uses denote its adaptogenic properties, the reason why it is often called the Peruvian ginseng today. It is the subject of numerous studies underway, and preliminary results point to its effects on the endocrine system.

Lepidium meyenii is a plant species that belongs to the Brassicaceae family, which comprises over three thousand species of edible plants called cruciferous vegetables. Hence, maca is related to many green leafy vegetables such as cabbage, broccoli and cauliflower, among others. Like these vegetables, maca contains an assortment of organic compounds that display bioactive properties.

Lepidium peruvianum refers to the same species. Modern herbalists argue that it is a more accurate scientific name for maca, though Lepidium meyenii remains in use in the scientific community. Until only recently, maca was exclusively cultivated in the Andes of Peru. Due to an increased interest in alternative forms of medicine in North America and Europe, it has enjoyed a sudden surge in popularity in the past few years.

Enhances Stress Resistance

Maca is marketed as an adaptogen, a natural remedy for stress. It has been compared to ginseng a number of times, earning itself the moniker Peruvian ginseng. Maca and ginseng do not interact with hormones in the body but rather contain phytochemicals that directly act on endocrine glands, including the hypothalamus, adrenals, and thyroid glands. These organs are pivotal to better management of stress. Several herbalists argue that maca is even more potent than ginseng in that it is believed to affect almost all endocrine glands and create a homeostatic effect on the chemical compounds that they secrete.

Modulates Energy Metabolism

The nutritional profile of maca has been described to be a combination of the nutrients found in whole grains and green leafy vegetables. It contains significant amounts of amino acids and dietary fiber. Its carbohydrate content accounts for 60 per cent of its dry weight, with emphasis on its low glycemic index. Its active constituents enable its carbohydrates to break down at a slow pace and release glucose into the bloodstream without raising blood sugar levels. By so doing, it provides the energy needed to fuel physical activities and athletic performance for extended periods of time.

Improves Sexual Performance

Maca is a popular aphrodisiac. In the old days, Inca warriors consumed large quantities of maca roots for the sole purpose of achieving desired virility. In addition to its energy-boosting and stress-relieving effects, regular intake of maca impacts sexual health as it contains organic compounds that stimulate gonadal tissues, especially in men. Randomized clinical trials have observed that maca affects semen quality, increases sperm count, and improves sexual performance, making it an ideal choice of supplement for men.

Maca root is an excellent herb for men and women. You can gain energy as well as a boost in energy with Maca root. Try maca root and feel the difference it can make on your life!

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What is the Amino Acid Taurine and How Does It Boost My Health
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Date: April 26, 2011 02:26 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is the Amino Acid Taurine and How Does It Boost My Health

Taurine is a nutrient that improves cellular processes by regulating mineral salts in the human body. Many people consider it as an amino acid as it is derived from seafood and meats. It is not an amino acid in the strictest sense, but a naturally occurring sulfonic acid. It is pivotal to removing the water in the bile. Bile acids are produced in the liver in the presence of taurine and stored in the gallbladder.

Enhances Physical Capacity

Many energy drinks describe taurine as an active ingredient. Several groups of researchers believe it affects athletic performance, drawing on its biological roles. For one, taurine is necessary for the upkeep of skeletal muscles, and in athletes appears to lengthen duration of physical exertion. Also, it is implicated in chemical reactions in the nervous system, boosting mental clarity.

Counteracts Hypertension

There is evidence that taurine has an effect on blood flow. In the circulatory system, taurine is important to regulating the level of water and minerals. It is widely accepted that it modulates the movement of elements and their metabolites in the blood, such as calcium, potassium, and sodium. In fact, taurine has been observed to significantly decrease high blood pressure in hypertensive patients.

Promotes Liver Health

Taurine is especially good for the health. Numerous studies have noted the effects of high levels of taurine on liver cells. It has been proven effective in removing any adiposity in the organ. Clinical trials have published results that emphasize its benefits to people with liver diseases, such as hepatitis and cirrhosis. It has also been observed that high intake of taurine counters hangover.

Lowers Serum Lipid Levels

In the liver, taurine plays an important role in inhibiting the releases of apolipoproteins, a class of proteins that bind with lipids to form lipoproteins. Apolipoprotein B makes up very-low-density lipoproteins and low-density lipoproteins, or what we refer to as bad cholesterol. This is the reason why taurine has been suggested to help people afflicted with cardiovascular diseases.

Normalizes Blood Sugar

It has been postulated that taurine protects the beta cells of the pancreas, the organ responsible for the manufacture of the insulin. Patients diagnosed with type 1 diabetes mellitus have been reported to experience an improvement in insulin levels. Taurine is also helpful for type 2 diabetes as it also appears to enhance glucose sensitivity of cells, thereby decreasing glucose levels in the blood.

Scavenges Free Radicals

Taurine is an antioxidant known for its wide-ranging benefits. It is almost always associated with oxidative stress brought on by physical exertion as it protects the skeletal muscles from the damaging effects of free radicals. More importantly, it protects the liver, the pancreas, and the circulatory system from the toxic by-products of metabolism, notably during oxidation of chemical compounds.

Given the health benefits of Taurine, everybody should be taking some daily!

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What is Oligonol Good for and How Does It Boost My Health?
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Date: March 22, 2011 03:42 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What is Oligonol Good for and How Does It Boost My Health?

Oligonol is the first ever nutritional supplement to contain low molecule polyphenolic oligomers. These polyphenols are derived from the plant Litchi chinensis, also known as lychee in the vernacular. The name oliginol is a portmanteau for oligomer polyphenol, which is widely touted to display bioavailability far superior to high molecular weight polyphenols present in most antioxidant supplements and the plants that they are extracted from. It boasts the most recent innovation of producing higher biological activity by using the low molecule technology developed by the Faculty of Pharmaceutical Sciences of Nagasaki University in collaboration with Amino Up Chemical Co. Ltd.

Polyphenols have long been known to create health effects that are antioxidant in nature. These organic compounds have been tied to quenching reactive oxygen species, or ROS, a natural by-product of oxygen metabolism. ROS like free radicals are in fact deployed by cells in response to potential threats such as invasive pathogens. Given the high reactivity of free radicals, each cell releases endogenous antioxidants to scavenge ROS. However, the body’s antioxidant defense becomes compromised with continued exposure to stress.

At the cellular level, an imbalance between ROS and antioxidants creates a chain reaction termed oxidative stress, which damages cellular organelles and even DNA. This is when antioxidant supplements come to the rescue. Plant-based polyphenols such as those found in teas is widely believed to neutralize free radicals. Those found in lychee are of special note in that they are particularly helpful against oxidative stress. The proprietary low molecule technology of Amino Up Chemical Co. Ltd. processes these already potent polyphenols into more effective monomers and short-chain oligomers.

Protects Cardiovascular Health

Since oligonol was made available nearly two years ago, there have been a number of studies looking into its medicinal potential. A few of the earliest researches were double-blind, placebo-controlled clinical trials that investigated its effects on the cardiovascular system. It has been observed that oligonol appears to lower platelet reactivity, contributing to dilation of peripheral vessels. By so doing, it effectively promotes blood flow, which results in an increase in body temperature.

Counteracts Physical Fatigue

Recovery to fatigue induced by physical exertion is one of the benefits of oligonol that have been well investigated. In one single blind, placebo controlled study involving 47 participants, intake of oligonol lowered post exercise fatigue. The oligonol group of amateur athletes between 18 and 22 of age took two 100-mg oligonol capsules in two 26-day periods with a 9-day wash-out period and saw a noticeable improvement in fatigue recovery in comparison with the control group.

Reduces Visceral Fat

Oligonol continues to excite researchers from around the world with the publication of the study on its effects on visceral fat. There are cell-signaling protein molecules released by adipose tissues that are considered deleterious to human health, and thus called bad factor. Adiposity has been tied to higher mortality, with people having larger waists especially susceptible to many known diseases. Supplementation of oligonol has seen a sharp decrease in abdominal circumference and overall subcutaneous fat.

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Is AHCC Good for the Immune System? How So?
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Date: March 02, 2011 02:44 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Is AHCC Good for the Immune System? How So?

AHCC And Immune Health

Active Hexose Correlated Compound, or AHCC, is one of the most commonly used food supplements in Japan largely owing to its effective immune-boosting properties when successfully absorbed by the human body. The earliest important study concerning its activities in the immune system was published in the early 1990’s at Tokyo University, triggering a sudden rise in popularity among consumers in Japan, where it is sold over the counter.

Activates White Blood Cells

It has been observed in the past few years that AHCC boosts the immune system in many different ways in that it participates not only in the innate immune system but also in the adaptive immune system. Of special note is the significant increase in certain types of white blood cells, including natural killer cells, or NK, and macrophages. NK cells are in the employ of the innate immune system and responsible for the disposal of cells infected by viruses. They are often the first line of defense against common viruses such as herpes, containing the damage that viral infection spreads while waiting for specified mechanisms of the adaptive immune system. This is when macrophages come into play along with a cohort of lymphocytes. Their relatively bigger size allows them to effectively engulf pathogenic cells and the enzymes they contain break these pathogens down.

Removes Antigens and Toxins

AHCC also influences the production of antigen presenting cells, or APC. In a double-blind, placebo controlled study involving healthy individuals there was a significant increase in the quantities of APC, notably dendritic cells, in comparison with the baseline, and proteins released by lymphocytes called interferon. Both APC and interferon facilitate the detection of antigens and toxins created by invasive foreign bodies and alert the rest of the immune system of their presence. Dendritic cells are considered the most important group of all APCs in that they present a wide range of antigen presentation by way of phagocytosis or endocytosis, two different ways of catching antigens. By so doing, they make it easier for white blood cells to eliminate antigens and other toxic substances.

Defends against Cancer Cells

Cancer patients are the group of individuals that have benefited the most from AHCC. Early studies yielded data that are now being used to enhance the quality of life of those diagnosed with cancer. Indeed boosting the immune system has proven to play a part in the battle against cancer, and AHCC stimulates the immune system to manufacture a class of white blood cells that actively defend the body against cancer cells by causing tumor cells to die and on the same principle delay the proliferation of malignant cells.

There have been extensive clinical trials well underway in many countries, including China, South Korea, Thailand, Spain, and the US. These studies aim to that rigorously test its efficacy. In fact, AHCC belongs to the group of nutritional products tied to alternative medicine that has been supported by an abundance of data in connection with its safety and recommended dosages.

If you are battling disease, give AHCC a try.

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Gotu Kola And Memory
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Date: September 15, 2009 04:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Gotu Kola And Memory

For centuries, gotu kola has been used in India and the islands of the Indian Ocean as a tonic and medicinal remedy. The herb was thought to increase longevity and improve energy. It was used in ancient days to treat leprosy, calm nerves, increase mental and physical power, stimulate and rejuvenate the brain, prevent nervous disorders, and avoid mental fatigue and senility.

This herb is considered to be one of the best herbal tonics, which is a substance that works to put the body into balance. A tonic makes sure that everything is working properly, while an herbal tonic helps to promote an optimum state in the body systems. This herb is responsible for gradually building the nervous system as a nervous system tonic. Gotu kola has been used for many different maladies, which include nervous disorders, deficient mental function, memory problems, epilepsy, and schizophrenia. The herb works by cleansing and purifying the blood by neutralizing acids and helping the body defend itself against toxins.

Research has found that an ingredient in gotu kola, known as asiaticoside, is responsible for speeding the healing of wounds. This ingredient is considered a blood cleanser and is also effective for diseases of the lungs. The herb stimulates the capillaries and helps to improve brain function, varicose veins, and hypertension.

Gotu kola is often used to increase mental function and performance. A variety of studies have confirmed this herb’s ability to improve brain function. It is often prescribed in Europe and India for this purpose. Studies done in India have found the water extract of fresh leaves helps to improve memory and learning. Additionally, it was found to help overcome the negative effects that are associated with stress and fatigue.

Additional clinical trials in India have found that gotu kola is able to help increase the IQ and mental ability of mentally retarded children. The children that were involved in this study showed improved mental capacity and behavior. This herb was given to children in combination with capsicum and ginseng. This improved behavior and mental capacity can help individuals who have mental and learning disabilities to achieve a higher quality of life.

In ancient times, gotu kola was used to heal wounds and soothe cases of leprosy. One of the first studies done on this herb was with cases of leprosy. The asiaticoside content found in gotu kola has been used for years in Europe and the Far East to cure leprosy and tuberculosis. Recent studies on this herb center more on its healing ability. Gotu kola seems to be able to accelerate the healing of wounds and skin diseases. Additionally, it has been shown to be beneficial in helping repair tissue after surgery and trauma. The herb has the ability to strengthen veins and repair connective tissue, while nourishing the motor neurons.

The entire gotu kola plant is used to provide alterative, antiasthmatic, antispasmodic, blood purifier, diuretic, and nervine properties. The primary nutrients in this herb are catechol, epicatechol, magnesium, theobromine, and vitamin K. Primarily, gotu kola is extremely helpful in dealing with aging, arteriosclerosis, high blood pressure, poor circulation, fatigue, heart problems, hypoglycemia, leprosy, memory loss, mental problems, nervousness, and senility.

Additionally, this herb is beneficial in treating blood impurities, depression, dysentery, fevers, headaches, insomnia, liver ailments, menopausal symptoms, pituitary problems, psoriasis, rheumatism, schizophrenia, thyroid problems, tonsillitis, effects of toxins, tuberculosis, varicose veins, lack of vitality, and wounds. For more information on the many beneficial effects provided by gotu kola, please contact a representative from your local health food store.

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Omega-3
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Date: July 08, 2009 10:50 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega-3

The headline "Doubts over heart claims of omega-3 fats" was published in March of 2006 in the world's largest international news agency, Reuters. This article reported on the findings of a study on omega-3 fats and heart health, which published the exact same month in the British Medical Journal. The article found in Reuters claimed that the systematic review of 89 studies led to the conclusion that there was no substantive evidence that omega-3 fats actually protected individuals against cardiovascular disease or cancer. The New Zealand Herald picked up this article and announced that the heart-healthy advice to eat more oily fish was incorrect, as it advised its readers to put fish oils on the top of the list of medical beliefs that turned out to be myths.

In actuality, the omega-3 investigation, conducted by Lee Hooper and coworkers at the University of East Anglia School of Medicine, was a meta-analysis, as it combined data from several available clinical trials. Meta-analyses are highly speculative due to the differences in the scientific protocols between the included studies, which can lead to difficulty in exposing a common factor. A good meta-analysis is often useful to put contradictory evidence into perspective. However, a poorly designed analysis can lead to bad science and faulty conclusions.

This Hooper analysis was a review of 48 randomized controlled trials, along with 41 cohort studies. However, the investigation only used as few as 15 controlled trials and 3 cohort studies in compiling the data. Included in this analysis were studies that had very small sample sizes and provided little data on the effects under investigation. Extremely low death rates in several of the studies that were included worsened the situation, which resulted in a very large confidence interval and a lower analytical power than what was expected. Additionally, there was a large degree of difference among the included studies. Some of them had death rates in their control groups as low as 0.5%, while others had extremely high control-group death rates exceeding 15% and 22% in two cases. This fact indicates that there were large disparities in the health of subjects. This much heterogeneity among subjects requires a high degree of analytical power in order to produce meaningful results. This was something that the Hooper study lacked.

When addressing the above issues, the authors of the study pointed out that “there were too few events such as deaths, associated cardiovascular events, and incidences of cancer to rule out the possibility of important effects from various interventions.” This basically means that the numbers produced in the study produced results that didn't show much of anything. In a case like this, a person should be extremely cautious as to dismissing a possibly association based on negative results. Dr. Mike Knapton, the Director of Prevention and Care for the British Heart Foundation cautioned the public that they should not stop consuming omega-3 fats or eating oily fish as a result of this study. The wise advice given by Dr. Knapton, however, was not enough to stop the media from fabricating stories and devaluing the necessity for omega-3 fats.

The fact is that omega-3 when taken on a consistent basis can help reduce cholesterol and improve cardiovascular health. Look for high quality omega-3 fish oil that is molecularly distilled at your local or internet health food store. Always select name brands to ensure quality and purity of the product you purchase.

*Statements contained herein have not been evaluated by the Food and Drug Administration. Omega-3 fish oil is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional health care provider before changing any medication or adding Vitamins to medications.

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Natural Vitamins under Attack
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Date: June 29, 2009 02:53 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Natural Vitamins under Attack

The value of nutritional supplements in protecting and promoting human health has been intensely debated in recent years throughout the scientific and medical community as well as the national press. Many researchers believe that supplements provide a convenient and effective way to supply the optimal amounts of essential nutrients that are necessary for supporting long-term health, while others argue that there is no proof that supplements provide any real health benefits at all.

A lot of the debate has been published by media that is more interested in selling papers than reporting the truth. Because of this sloppy reporting and distorted information, the public has been unnecessarily alarmed, causing them to lose trust in complementary health care. It is crucial that this false information be addressed before harm that is irreversible is done to an industry that is committed to natural approaches to wellness and a public that is increasingly confused as to where to turn for truthful advice on preventing disease and achieving optimal health. The mixed messages that have been reported in the headlines have confused both health-conscious consumers and medical practitioners, as one day they’re told something is good for them and the next day they’re told it is not.

If there is any consolation to this whole thing, it may be helpful to understand that science never progresses smoothly, as there are always new findings that appear to disprove long-held beliefs. Controversy is necessary for change, as it paves the road that science must travel in order to arrive at the real truth. Unfortunately, bias in the media and conflicts of interest add an unnecessary element to finding the real scientific truth.

When looking at the recent studies that have been negated, there are several explanations that arise for the findings that seem to contradict prevailing scientific evidence. First of all, several long-term dietary intervention trials have recently come about which were developed in the early 1990s before good and bad fats were differentiated. Because of this design, these studies simply assume that all fat is the same, and to reduce fat, one must cut out all kinds of fat. Secondly, it has been proven that there will always be a statistical fluke in a bunch. Therefore, out of 100 clinical studies to investigate a particular effect, probability states that five of these studies, no matter how well they are designed, will show results that are not real.

Thirdly, it is expected that about one fifth of clinical trials that investigate a particular effect will not have the needed number of subjects to produce a result that is statistically significant. This is so because in most clinical trials there is only an 80% probability of finding a real result, which is known as the power of the test. Because of this, there is up to a 20% chance completely missing the mark and failing to find a difference when one actually exists. Finally, some investigations are just bad science, as they are improperly conducted, poorly reported, and inadequately reviewed. Unfortunately, these studies attract a great deal of attention from the media, which has been the case recently.

Natural vitamin supplements can feed the body and help the body fight disease and stay wall. The foods we eat determine what kind of health we will have, if we eat poorly, we will live with poor health. This is why we should consume a multiple vitamin and mineral as well as herbs and food concentrates to help supply our diet with the needed nutrients to sustain and maintain a good healthy lifestyle. Look to your local or internet health food store for vitamins, herbs, and food concentrates.

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Huperzine And Memory
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Date: December 04, 2008 01:20 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Huperzine And Memory

Chinese club moss goes by the name Huperzia serrata, and gives its name to the sesquiterpene alkaloid it contains: huperzine A. This alkaloid has been found to be a superstar in the arena of brain-saving treatments for conditions such as Alzheimer's and age-related senility. Studies in China have found up to 60% improvements in the cognitive functions of such patients, and its potential has been recorded in the Journal of the American Medical Association. This is no mere folk remedy, and is the subject of serious study.

Known as Qian Ceng Ta, Chinese club moss has been a part of traditional Chinese medicine for centuries for the treatment of fever and inflammation, which is not surprising considering that most plants contain antioxidants and anti-inflammatories. However, what is unusual is the fact that it has also been found effective in treating some forms of dementia and depression, and also helps to reduce the incidence of panic attacks in those susceptible to them.

Not only that, but the plant has been found to possess diuretic properties, and a reduction in the swelling associated with water retention could also help to reduce the pain and other effects of swelling and inflammation. However, for now it is its effect on the brain that we are concerned, and research has indicated the likely mechanism by which huperzine A works.

Huperzine is an enzyme inhibitor - specifically inhibiting the enzyme acetylcholinesterase that breaks down acetylcholine, a neurotransmitter involved in the processes of memory, learning and mood. Outside the brain, it is involved in the movement of skeletal muscle tissue as well as in the regulation of cardiac and other smooth muscles such as those of the blood vessels.

When acetylcholinesterase (AChE) attacks acetylcholine (ACh), the latter attaches to a chemical site on the enzyme where it is then destroyed. It is a deliberate function of the body, designed to terminate a synaptic transmission. The purpose of a neurotransmitter is to allow the transmission of an electrical impulse form one nerve cell to another over a gap between them known as a synapse. Once the transmission has been completed, the enzyme can destroy the neurotransmitter, and then another takes its place. In fact one molecule of AChE can destroy around 5,000 molecules of ACh.

However, with age and for other reasons, these neurotransmitters can become depleted so that it becomes increasingly more difficult for brain cells to communicate with each other, and their destruction becomes undesirable. There are drugs available to help prevent this happening (e.g. donepezil, galantamine and tacrine), and so help to improve the memory and mental function of people as they grow older or contract conditions such as Alzheimer's disease.

Huperzine A has been found to take up the site in the acetylcholinesterase molecule that would normally have been used by the acetylcholine, and so save it from destruction. The more Huperzine A molecules present, the more acetylcholine available to pass messages between brain cells, and the stronger the cognitive function of the subject or patient. The pharmaceutical drugs mentioned in the previous paragraph work in exactly the same way.

This is a very specific reaction, one molecule adopting exactly the same space as the other, and has been proved scientifically by comparing the physical shapes of the two molecules. It's just like a jigsaw puzzle, where only one piece can fit into each position. Except here there are two: Huperzine A and acetylcholine both fit into the exact same place in the chemical structure of the acetylcholinesterase molecule.

The biochemistry of the reactions involved is very complex, and shall not be discussed here, but the upshot is that Huperzine A can do exactly the same job as modern drugs to avoid this hydroxylation of the ACh needed for the proper functioning of your brain.

In fact, clinical trials have indicated Huperzine A not only to be comparable in effect to the drugs current used, but also likely safer with respect to the possible side effects. This has still to be confirmed, but the National Institute on Aging is currently carrying out a trial to evaluate this claim in tandem with its effect on Alzheimer's disease. It has also been examined at Harvard University for its effect on epilepsy on patients with whom alternative pharmaceutical treatments have been unsuccessful.

Another suggested benefit of Huperzine A is that it is an NMDA (N-methyl D-aspartate) receptor antagonist that provides protection against damage to the brain by an excess of glutamates, and that it can also help to protect nerve cells from damage. Since NDMA is responsible for the transmission of some types of pain, the antagonist can also act as an analgesic.

There are other benefits that Chinese club moss can provide, and myasthenia gravis is one of them. Although relatively rare, this is a serious condition in which acetylcholine receptors are deactivated on muscle cells. This is achieved through the autoimmune system malfunctioning and creating antibodies against the receptors, and the end result is paralysis and respiratory failure.

Huperzine A reduces the AChE available and so might possibly enable the acetylcholine to work more effectively and delay or even stop the deterioration of muscle function. When people hear of muscle paralysis they frequently forget that breathing requires muscle function, as indeed does your heartbeat. This is currently surmise, and studies are being carried out to determine whether or not this usage of Huperzine A is viable.

Another promising application of Chinese club moss extract is in preventing organophosphate poisoning. These pesticides permanently suppress acetylcholine. This results in seizures due to a lack of interruption of the signals from nerves to muscles. The seizures can result in rapid death from uncontrollable seizures, or from permanent contraction of the diaphragm muscle that allows breathing. Although no human studies have yet been carried out, animals given Huperzine A prior to organophosphate exposure have survived without seizures.

There are no doubts that Chinese club moss and the Huperzine A extracted from it are effective in preventing the suppression of acetylcholine, and in permitting the proper activity of this important neurotransmitter. It is finding an increasing number of potential uses beneficial to the human body, not the least of which would be a partial remedy for some of the effects of dementia and Alzheimer's disease.



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Phytoestrogen - Plant Estrogen
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Date: September 25, 2008 05:57 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Phytoestrogen - Plant Estrogen

Phytoestrogens mainly belong to a group of phenolic compounds known as flavonoids: the coumestans, prenylated and isoflavones are three of the most active in estrogenic effects. Phytoestrogens are not considered as nutrients because the lack of in the diet will not produce any characteristic deficiency syndromes nor do they participate in any essential biological function. Phytoestrogens are considered archi-estrogens (naturally occurring) and as dietary phytochemicals they are considered as safe and effective in its estrogenic activity.

Phytoestrogen content varies in different foods, and may vary significantly within the same group of foods due to the way these foods are grown such as soil content. Phytoestrogen when consumed as a treatment for menopause was well tolerated and caused no changes in liver enzymes, creatinine levels, body mass index, or blood pressure. Phytoestrogen is found in a wide variety of edible plants and generally display both estrogenic and anti-estrogenic properties.

Canadian researchers examined the content of nine common phytoestrogens foods in a Western diet, foods with the highest relative phytoestrogen content were nuts and oilseeds, followed by soy products, cereals and breads, legumes, meat products, and processed foods that may contain soy, vegetables, fruits, alcoholic, and nonalcoholic beverages. Researchers are also studying if phytoestrogens can prevent prostate cancer, preliminary results are promising. Researchers focused primarily on the compound isoflavones because of its greater abundance in soy plus it exhibit estrogenic properties in the same strength as the other phytoestrogens compounds..

Isoflavones are structurally similar to the estrogen in human body’s, and thus have been shown to possess both estrogenic and anti-estrogenic activity. Isoflavones may directly inhibit bone re-sorption and prevent the onset of osteoporosis. The weak estrogenic effects of isoflavones have been postulated as being protective against various forms of cancer as well. Being that isoflavones are chemically similar to estrogen, one can take isoflavones as an estrogenic replacement with little to no side effects.

Two other clinical trials suggest that over the short term, soy isoflavones may reduce lumbar spine bone loss in peri- and postmenopausal women. Red Clover contains all four estrogenic isoflavones: biochanin formonoetin daidzein Genistein. Much research has been performed on soy and red clover based phytoestrogens sources. We do not eat much red clover and so we will focus more on soy sources.

Soybeans contain large amounts of isoflavones or phytoestrogens such as genistein, daidzein, glycitein, and isoflavones. Soybeans display a biological effect when ingested by humans and animals. Soybean oil is the most commonly used vegetable oil in the United States and Europe. Soybean oil contains approximately 61 percent polyunsaturated fatty acids making it a healthy alternative to other oils currently available on the market for cooking.

Soybeans contain high levels of phytoestrogens and are the most widely used oil in the United States, and is sold as either pure soybean oil or as a main ingredient in vegetable oil. Most of the supplements on the natural foods market contain isoflavones derived from soybeans or red clover and some contain botanicals such as black cohosh.

Phytoestrogen flavonoids and lignan exhibit significant antioxidant activity which is great for those anti-aging minded individuals. The antioxidant activity in flavonoid and lignan helps support breast, heart and bone health. Antioxidants can reduce free radical damage in the body as well as reduce oxidative stress which causes aging. We all know that over time we age, phytoestrogens might help one age more gracefully.

Finally, phytoestrogens, sometimes called "natural estrogens", are a diverse group of naturally occurring non steroidal plant compounds that, because of their structural similarity with estradiol (estrogen), have the ability to cause estrogenic or/and anti-estrogenic effects in the body. Isoflavones are found in high concentration in soy bean and soy bean products changing ones diet to more soy based foods or taking a phytoestrogens supplement can help reduce estrogen related cancers and maybe even prostate cancer.




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Supplements to Fight Prostate Cancer
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Date: July 29, 2007 11:41 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Supplements to Fight Prostate Cancer

Prostate Cancer and Nutritional Supplements

 

Years of research have discovered that the foods a man chooses to eat (or doesn’t eat) can have a profound impact on the health of his prostate gland. Because of this close nutritional link, prostate cancer may be the most preventable type of cancer (after smoking-related lung cancers).

Recently, there has been an incredible amount of research and investigation of prostate cancer. Many of these studies have explored the use of certain nutrients to prevent and actually treat prostate cancer. These nutrients, calcium D-glucarate selenium, broccoli, green tea, maitake, and lycopene are powerful prostate cancer fighters. All are available as nutritional supplements that men can take every day as an important part of a healthy diet.

In this issue of Ask the Doctor, we will discuss prostate cancer and how men can actually prevent it with the use of these six nutrients. Plus, if men already have prostate cancer, these nutrients can be an important part of their treatment regimen in fighting their disease.

 

Q. What does the prostate gland do?

A. The prostate is a gland in a man’s reproductive system. It makes and stores seminal fluid, the milky fluid that nourishes sperm. This fluid is released to form part of the semen. The prostate is about the size of a walnut and it is located below the bladder and in front of the rectum. The prostate actually wraps around the upper part of the urethra, the tube that empties urine from the bladder through the penis.

 

Q. What are the symptoms of prostate cancer?

A. Early prostate cancer often does not cause any symptoms. However, many symptoms of prostate cancer are also symptoms of other problems with the prostate, such as an infection or benign prostatic hyperplasia, a prostate enlargement associated with age-related changes.

A man who has any of these symptoms should see his health care practitioner for evaluation:

-A need to urinate frequently, especially at night

-Difficulty starting urination or holding back urine

-Inability to urinate

-Weak or interrupted flow of urine

-Painful or burning urination

-Difficulty in having an erection

-Painful ejaculation

-Blood in urine or semen

-Frequent pain or stiffness in the lower back, hips, or upper thighs.

 

Q. Are certain men more prone to get prostate cancer?

A. Age is the biggest risk factor: most prostate cancers occur in men over 65 years of age. A man’s risk for developing prostate cancer is higher if his father or brother has had the disease. African-Americans are at higher risk for the disease. Mechanics, farmers, sheet metal workers, and workers exposed to cadmium have also had high rates of prostate cancer.

 

Q. How is prostate cancer diagnosed?

A. A man who has any of these risk factors may want to ask his health care professional whether to begin screening for prostate cancer (even though he does not have any symptoms), what tests to have, and how often to have them.

The usual prostate tests include: Digital rectal exam: the doctor inserts a lubricated, gloved finger into the rectum and feels the prostate through the rectal wall to check for hard or lumpy areas.

Blood test for prostate-specific antigen (PSA): a lab measures the levels of PSA in a blood sample. The level of PSA may rise in men who have prostate cancer, benign prostatic hyperplasia (a non-cancerous enlargement of the prostate gland), or an infection in the prostate.

These tests will only determine if there is a problem with a man’s prostate gland. They cannot determine if the problem is cancer. Only a biopsy of a sample of prostate tissue can reveal the presence of actual prostate cancer.

 

Q. What nutrients help prevent or treat prostate cancer?

A. The prostate health nutrients, calcium D-glucarate, selenium, broccoli, green tea, maitake, and lycopene, each work in unique ways. Some help men’s bodies’ work more effectively some keep cancer cells from growing, while others actually kill prostate cancer cells. Let’s discuss each nutrient and how it works.

 

Calcium D-Glucarate

It is a troubling fact of modern life that we are continuously exposed to cancer-causing chemicals and toxins. These toxins come in part from contaminants in the food we eat and pollutants in the air we breathe. There are also “natural” toxins that are produced in our bodies. Excess hormones, such as estrogen and testosterone, can cause cancer when they are no longer needed. Cancer causing chemicals not only initiate cancer, but exposure to them can also cause existing cancers to grow bigger, stronger, and more deadly.

Our bodies do a fairly good job of eliminating some of these toxins before they can cause us harm. In the liver, the toxin is bound or attached to a chemical called glucuronic acid. The bound toxin is then excreted in bile and eventually eliminated as a waste product in the stool. However, yet another chemical, an enzyme called glucoronidase, can break this bond between the toxin and glucuronic acid. When this happens, the hormone or toxin is released back into our bodies, capable of causing us harm once more. The longer the toxins and excess hormones are in our bodies, the greater the chances they can make us seriously sick. Scientists have discovered that increased glucuronidase activity in the body is strongly associated with prostate cancer.

Fortunately, scientists have also discovered that a natural substance found in foods, calcium D-glucarate, can greatly reduce the activity of glucuronidase. Calcium D-glucarate helps our bodies keep the harmful toxins and chemicals bound to glucuronic acid. While CDG is found in fruits and vegetables, the amounts may not be sufficient to maintain effective levels to stop beta-glucuronidase. CDG has been shown in many experimental studies to significantly stop prostate cancer growth. Studies have shown that by taking calcium D-glucarate, our bodies and get rid of the toxic chemicals and excess hormones that might stimulate cancer formation.

 

Selenium

Selenium is an essential trace mineral fund in the soil. Both plant foods like oatmeal and meats that we eat, such as chicken and beef, contain selenium. How much selenium, however, is difficult to determine. This is because the amount of selenium in soil, which varies by region, determines the amount of selenium in the plant foods that are grown in that soil. Animals, too, will have varying levels of selenium in their muscle, depending on the amount of selenium in their feed. The actual selenium level in the grasses and grains that make up animal feed reflect the amount of the selenium in the soil where they grew.

A major antioxidant, selenium slows down aging, keeps our skin supple, and helps prevent dandruff. Selenium also keeps our blood vessels healthy and protects us from heart disease. However, some of selenium’s most powerful effects are on the prostate gland.

In a recent study, researchers recruited 974 men to take part in a large clinical trial to determine if selenium could prevent cancer. Half of the men were given selenium supplements and half were given a placebo. Researchers, who did know which group got the placebo, watched and recorded the men’s progress. The researchers were amazed to learn that selenium cut the rate of prostate cancer by 63%!

The results of this study were so impressive that it has led to many other studies of selenium and prostate cancer. In fact, researchers at the Arizona Cancer Center and the Arizona College of Public Health in Tucson are currently studying the effect of selenium on prostate cancer in four ongoing clinical trials.

 

Broccoli

Scientists have observed over for a long period of time, that men who eat lots of broccoli have a lower risk of getting prostate cancer. It seems that sulforaphane, a compound abundant in broccoli, is the secret ingredient responsible for this connection. Sulforaphane increases certain enzymes in the body, called phase 2 enzymes, which deactivate cancer-causing chemicals. In lab experiments, prostate cancer cells that were exposed to sulforaphane, the compound inhibited the growth of the cancer cells up to 80 percent.

 

Green Tea

There is a potent plant substance in green tea that is a very effective killer of prostate cancer cells. A recent study tested four common components of green tea and determined that one of these compounds, epigallocatechin gallate or EGCG, has a special affinity for prostate cancer cells. Scientists discovered that EGCG can stop the growth of prostate cancer dead in its tracks. The chemical structure of EGCG is very similar to substances in red wine and cruciferous vegetables, known cancer killers.

 

Maitake mushroom

For many years, maitake mushrooms have been linked to good health in those who eat them. Called “dancing mushrooms” (possibly due to their wavy, rippling appearance or possibly due to the little dance of joy mushroom hunters perform when they find them in the woods), maitakes contain an important compound called D-fraction.

A recent study at New York Medical College showed that maitake D-fraction destroyed 95% of human prostate cancer cells in lab experiments.

 

Lycopene

Some of the most exciting nutritional news in relation to prostate health involves lycopene. This carotenoid is found primarily in tomatoes, and men who eat lots of cooked tomatoes have very low rates of prostate cancer. Because promising preliminary reports demonstrate that lycopene can actually kill prostate cancer cells, there has been an explosion of lycopene and prostate cancer studies.

In one of these studies, 32 prostate cancer patients ate a pasta meal covered with three-fourths cup of tomato sauce every day for three weeks. Results showed their PSA levels dropped two points. Even signs of DNA damage dropped sharply. The ability of lycopene to drop these levels in just three weeks has impressed researchers and scientists worldwide.

 

Q. Do I have to take each nutrient separately?

A. While you can purchase each one of these nutrients and take them separately, all of these nutrients are available in prostate health formulas. Make sure the formula you buy contains calcium d-glucarate, lycopene, and selenium, broccoli standardized to contain a minimum of 125 mcg sulforaphane, green tea, and maitake mushroom extract. Standardized ingredients provide consistently effective nutrients.

 

Q. What else can men do to prevent prostate cancer?

A. Adopting a healthy diet, including eating 5 to 9 servings of fruits and vegetables every day, eating several servings of whole grain cereals and bread, and reducing red meat consumption to 2 or 3 servings per week has been shown to reduce the risk of all kinds of cancer. In addition, the recent lycopene studies suggest that a diet that regularly includes tomato-based foods may help protect men from prostate cancer.

Men 50 years and older should have a digital rectal exam (DRE) and PSA test each year. African-Americans and those at higher risk should begin at age 40. Talk with your health care professional to determine how frequently the test should be done.

 

Conclusion

This year doctors expect to find 180,000 new cases of prostate cancer is the United States and 37,000 men will die of it. Prostate cancer is the second leading cause of cancer death in men. But there is hope.

More cancers are caught early and new treatments might help make it possible for men to live long and healthy lives following their diagnosis. By taking a few simple steps, men diagnosed with prostate cancer can take charge of their lives and overcome much of the fear and anxiety that accompany a cancer diagnosis.



--
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Active Coenzyme Q10
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Date: July 07, 2007 01:30 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Active Coenzyme Q10

Active CoQ10

 

The benefits of Coenzyme Q10 have become increasingly well-known. This important nutrient has been shown in clinical trials to improve heart function, reduce the side effects of certain drugs used to treat cancer, and slow the progression of serious brain diseases such as Parkinson’s disease. Now research has opened a new chapter in the CoQ10 story, highlighting the benefits of ubiquinol, the active form of CoQ10, to increase energy and stamina, and reduce some of he physical signs of aging.

In this issue of Ask the Doctor we will review the benefits of Coenzyme Q10, and discuss the differences between CoQ10 and its active form –ubiquinol.

 

Q. What is CoQ10?

A. CoQ10 is a natural, fat-soluble nutrient present in virtually all cells. CoQ10 also is known as ubiquinone. That’s because CoQ10 is ubiquitious and exists everywhere there is life. CoQ10 is vital to adenosine triphosphate (ATP) production. ATP is the energy-rich compound used for all processes requiring energy in the body. Although CoQ10 is produced by the body and exists in some limited dietary sources, these levels may be insufficient to meet the body’s requirements. CoQ10 levels diminish with age and as a result of dietary inadequacies and various disease states. Also, some drugs, especially a group of cholesterol lowering prescription drugs known as “statins,” (Pravachol, Zocor, Lipitor, etc.) significantly reduce CoQ10 levels in the body.

 

Q. What is ubiquinol? Is it the same or different from CoQ10?

A. Ubiquinol and CoQ10 are very closely related. Ubiquinone, or CoQ10, is the oxidized form of the molecule. This means it has to be converted to a non-oxidized form before it can perform its work. Ubiquinol is the active form of this nutrient. Our bodies convert CoQ10 to ubiquinol – which is the form needed to produce cellular energy. Until recently, it was not possible to use ubiquinol as a supplement because it is very unstable outside the human body. But research has now found a way to keep this molecule stable so it can be successfully taken in supplement form.

 

Q. If CoQ10 gets converted to ubiquinol anyway, can’t I just take CoQ10?

A. While it is true that our bodies can convert CoQ10 to ubiquinol, it isn’t true that we all do this equally well. In fact, as we age, our ability to convert CoQ10 to ubiquinol declines. And some people even have a gene that makes them less effective at this conversion than the majority of the population. IN fact, several common health issues have been associated with less than optimal ratios of CoQ10 to QH. For healthy people the ideal ratio is approximately 97% Ubiquinol to 3% CoQ10. But in people with diabetes, for example, the ratios have been found to range from 43% ubiquinol to 47% CoQ10 in mild diabetes, to only 24% ubiquinol to 76% CoQ10 in severe diabetes. These numbers are for men; the numbers for women vary by 2 to 5 percentage points.

So for older folks, the 30-50% of people who have the gene that impairs CoQ10 conversion, or for people who have serious health concerns, supplementing with ubiquinol instead of CoQ10 might be the smart choice.

 

Q. What are the health benefits of CoQ10 and Ubiquinol?

A. There have been many studies showing that CoQ10 is beneficial in treating and preventing heart disease and conditions such as high blood pressure atherosclerosis (hardening of the arteries), angina, and congestive heart failure (CHF). It’s been shown that heart attacks tend to occur when CoQ10 levels are low in the body. Exciting new research has found that CoQ10 in a unique delivery system supplementation may slow the progression of symptoms associated with neurological diseases such as Parkinson’s disease, ALS, Huntington’s disease and Alzheimer’s disease.

In addition, CoQ10 is beneficial for diabetes, immune dysfunction, cancer, periodontal disease, prostate cancer, and neurological disease. While the research on ubiquinol is still very new, it is reasonable to expect that its benefits will be equal to or perhaps even better than CoQ10, because it is the more active form.

 

Q. Why is CoQ10 especially important for preventing and treating heart disease, and for neurological diseases like Parkinson’s disease?

A. The heart and brain are some of the most metabolically active tissues in the body. Both require large amounts of uninterrupted energy, which means these tissues also need increased amounts of ubiquinol. Research has shown that many people with heart of brain diseases have serum CoQ10 levels that are lower than those of healthy people. Correcting such deficiencies often can produce significant results. However, these diseases become more common as we age – right at the time our ability to convert CoQ10 to its active form, ubiquinol, declines.

 

Q. How might ubiquinol be important for the heart?

A. Heart Health: A study on patients admitted to the hospital with an acute myocardial infarction (AMI) found that CoQ10 can provide rapid protective effects in patients with a heart attack if administered within three days of the onset of symptoms. Seventy-three patients received CoQ10 (120 mg/d). The study’s control group consisted of 71 similarly matched patients with acute AMI. After treatment, angina pectoris (severe chest pain signifying interrupted blood flow to the heart), total arrhythmias (dangerously irregular heartbeats), and poor function in the left ventricle (the essential chamber of the heart) were significantly reduced in the CoQ10 group compared to the placebo group. Total deaths due to sudden cardiac failure and nonfatal heart attacks also were significantly reduced in the CoQ10 group compared with the placebo group.

In another study, CoQ10 was studied in 109 patients with high blood pressure (hypertension). The patients were given varying doses of supplemental CoQ10 with the goal of attaining a certain blood level (greater than 2.0 mcg/l). Most patients were on medications to treat hypertension. Half the patients were able to stop taking some or all of their prescription drugs at an average of 4.4 months after starting CoQ10. The 9.4% of patients who had echocardiograms, performed both before and during treatment, experienced a highly significant improvement in heart wall thickness and function. This improvement was directly attributed to CoQ10 supplementation.

Congestive heart failure (CHF) is a debilitating disease that affects 5 million people in the U.S. It causes edema, difficult breathing, and impaired circulation. In another study, CoQ10 restored healthy heart function in CHF patients. Patients received 100 mg of CoQ10 or a placebo twice daily for 12 weeks. Before and after the treatment period, the investigators introduced a catheter into the right ventricle of patients’ hearts to determine the degree of CHF damage to the heart muscle. The patients’ heart muscles at rest and work improved significantly. The researchers concluded CHF patients would greatly benefit from adjunctive CoQ10 treatment. Since ubiquinol is the active form of CoQ10, it may be able to overcome the hurdles to providing maximum impact, most importantly, age and genetic related inefficiencies in converting CoQ10 to active CoQ10 (Ubiquinol).

 

And Neurological Health?: A study sponsored by the National Institutes of Health showed that supplementing with CoQ10 in a unique delivery system was associated with a slowing of the progression of Parkinson’s disease. Participants were divided into 4 groups and their physical skills (coordination, walking, etc) and mental skills were evaluated. Each group then received 300 mg, 600 mg, or 1200 mg of a special form of chewable CoQ10, or a placebo. The researchers evaluated the participants after 1, 4,8, 12, and 16 months of treatment. Each participant was again scored on motor, mental, and activities of daily living skills.

The results of the study showed that the people who took the highest dosage of CoQ10-1200 mg-experienced the least decline in their physical abilities. The results were so encouraging that the researchers will be continuing with new studies, suing higher dosages to see if the results can get even better.

Huntington’s disease (HD) is a devastating and degenerative inherited disease that is always fatal. In fact, no other medication, drug, or nutritional supplement has ever been shown to cause a decline in the progression of this terrible disease. A study compared CoQ10 against remacemide (an investigational HD drug made by AstraZeneca Pharmaceuticals), in 347 HD patients who were in the early stages of the disease. Remacemide blocks glutamate, the neurotransmitter scientists think may cause the death of brain cells that occurs in Huntington’s disease. While remacemide had no effect on the progression of HD, CoQ10 showed a trend toward slowing the disease by an average of 15%. This meant the HD group taking CoQ10 was able to handle every day activities of life a little longer than the patients taking remacemide or a placebo. They also were able to focus their attention better, were less depressed, and less irritable.

The 15% slowing of decline can result in about one more year of independence of HD patients. Needless to say, the gift of an additional year of health in the lives of HD patients is incredibly significant.

Because of these impressive results, researchers are hopeful that supplemental CoQ10 will have beneficial effects for people with other neurological diseases such as ALS and Alzheimer’s disease, too. Studies are under way to confirm these effects.

Using the active form of CoQ10 helps to assure that, regardless of age or illness, the CoQ10 can have the greatest impact.

 

Q. What have been the results of research studies with Ubiquinol?

A. One of the most interesting effects of Ubiquinol that has been reported so far is its ability to slow the physical signs of aging. In laboratory studies, administration of stable ubiquinol to mice forestalled the changes associated with aging – rounded spine, patchy fur and irritated eyes. While the mice who received ubiquinol did not necessarily live longer than the mice that didn’t, they lived better. But it is important to note that these mice were bred to die at a young age. Human studies are needed to determined true impact on longevity.

Additionally, supplemental, stable ubiquinol has been shown to increase physical energy and stamina. In an animal study, the length of time rats were able to run on a treadmill before getting tired was measured. The same rats were then given ubiquinol and the treadmill test was repeated. The length of time the rats were able to run before tiring increased 150 times.

 

Q. How can one supplement have applications for neurological diseases, heart health, and even the immune system?

A. Supplements often have more than one function, especially when it’s a substance like CoQ10, which is present in all parts of the body. All nucleated cells (most cells other than red blood cells) have mitochondria and all cells require energy to function. CoQ10 is vital to ATP production. Thus, CoQ10 has applications not only in neurological (neurons or nervous system cells) and cardiac health (myocardium or heart tissue), but also for the immune system.

 

Q. Should I take CoQ10 or ubiquinol? How much should I take?

A. While everyone can benefit from CoQ10 or ubiquinol supplementation, it appears that ubiquinol should be the first choice for older adults, people with known genetic inefficiencies in converting CoQ10 to ubiquinol, and for people with serious heart disease or neurological diseases such as Parkinson’s disease, who are otherwise supplementing with high levels of CoQ10. For people in overall good health, a high quality CoQ10 supplement with proven absorption is a good choice.

Take 200 to 300 mg of CoQ10 or 100 mg ubiquinol daily, depending on your health history. The safety of both forms has been tested, and no significant side effects reported. Occasional mild stomach upset may occur. Taking your CoQ10 or ubiquinol with meals usually alleviates this rare effect.

 

Conclusion
CoQ10 is not the only answer to the complex issues of heart disease, neurological diseases, or immune dysfunction; however, research indicates that it’s a bigger piece of the puzzle than physicians and scientists ever imagines. The more we study this naturally occurring compound, the more benefits we find. And with this new ability to provide CoQ10 in its active form, ubiquinol, for the first time, even greater benefits may be derived.

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ActiFruit with Cran-Max – Cleanse, Purify, and Protect the Urinary Tract*
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Date: July 06, 2007 02:12 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: ActiFruit with Cran-Max – Cleanse, Purify, and Protect the Urinary Tract*

ActiFruit with Cran-Max – Cleanse, Purify, and Protect the Urinary Tract*

 

One per day

  • Ultra concentrated
    1. Up to 7 times the antioxidant benefits of the leading brand of cranberry juice cocktail.
    2. Zero added sugars – compared to 25 grams of sugar in a serving of cranberry juice cocktail.

 

  • Other cranberry products require multiple doses throughout the day to be effective – up to 6 pills per day

 

Extended Release

  • Patented (#6,231,866 & 6,440,467) Bio-Shield® technology, exclusive to Cran-Max®
    1. Delivers the full spectrum of bioactive compounds
    2. Ensures natural extended-release absorption throughout the day.*

 

Clinically Studied

      • Boosts urinary tract health by 50% in clinical trials*1
      • First branded supplement clinically shown to protect the urinary tract*2

 

1 Stothers L. A randomized trial to evaluate effectiveness and cost effectiveness of naturopathic cranberry products as prophylaxis against urinary tract infection in women. Can J Urol. 2002;9:1558-62.

2 wheeler R Cran-Max for the treatment of chronic urinary tract infections. Data unpublished. Abstract available at //www.cranmax.com/studies_wheeler.shtml. 1998.

 

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Breast Cancer and Natural Supplements
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Date: May 11, 2007 10:47 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Breast Cancer and Natural Supplements

Breast Cancer and Nutritional Supplements

 

There is probably nothing more frightening for a woman than the discovery of a lump in her breast. Cancer and all its consequences quickly come to mind. This quick association may materialize, in part, because no woman is immune. Most have a friend, a sister, a mother, or a coworker who has been diagnosed with the disease. And they know how difficult dealing with this disease can be. Fortunately, 80% of all breast lumps are not cancerous. Most are cysts or a benign clump of tissue.

Over her lifetime, a woman’s breasts undergo many, many changes. From before puberty and on, breast tissue is continually evolving. Breasts often feel different before menstrual cycle, returning to normal a few days after. Pregnancy certainly causes changes in a woman’s breasts, as does breastfeeding. And as women age, breast tissue becomes less dense.

Because of these continual changes, breast tissue especially requires adequate nutrition. While everyone benefits from a healthy diet, there are additional nutrients from which women can specifically benefit.

In this issue of Ask the Doctor, we will discuss breast cancer and the vast amount of research that has explored the role nutrition plays in this serious and still deadly disease. Specifically, we will discuss how two B vitamins, calcium D-glucarate, broccoli extract, green tea, maitake mushrooms, and iodine can all help prevent breast cancer.

 

Q. How can these nutrients prevent breast cancer?

A. Scientists learn a lot about disease from simply observing what is happening around them. One observation that has been recognized for many years is that certain cultures have very low incidence of breast cancer. Women n China and Japan are good examples of this. Compared to women in America, Canada, and parts of Europe, Asian cultures have much lower breast cancer rates. It seems likely that something in their diet might be protecting these women from the disease because once Asian women adopt a western diet, their breast cancer rates climb.

Moms (and dads) have also learned a lot about diseases simply by observing what is happening in their families. They have notices that certain vegetables play a large role in the prevention of all types of diseases, including cancer. And, accordingly, they have been urging their offspring to eat their vegetables for several generations.

Building on these observations, scientists have designed and carried out many studies to determine what it is about these nutrients that can prevent breast cancer. What they have discovered, so far, follows. Let’s start with the B vitamins.

 

Vitamin B12

Deficiencies of this vitamin can result in a serious type of anemia. Nerve damage can also occur if B12 levels are too low. Researchers are now investigating whether breast cancer may, in part, be caused by a B12 deficiency as well.

At John Hopkins University in Maryland, two large but separate blood sample donations were evaluated against cases of breast cancer. In 1974, 12,450 blood samples were donated by female volunteers. In 1989, another 14,625 women again voluntarily donated samples of their blood. Cases of breast cancer that occurred in these groups of women were then recorded and their blood samples examined. Women, who had the lowest levels of B12 in their blood, had the highest rates of breast cancer.

Another study, this one taking place in a laboratory setting, discovered that vitamin B12, applied directly against experimental breast cancer cells, actually stopped the cancer cells from growing. The researchers conducting the experiment believe that giving vitamin B12 to women with breast cancer as part of a chemotherapy regime, might help keep the cancer in check.

 

Folic Acid

Low folic acid intake is linked to the development of all cancers. This is because folic acid is crucial to the making and continual repair of DNA, the molecule that carries our genetic code. A recent study discovered that high intakes of folic acid might actually reduce the risk of breast cancer. The researchers looked at the diets of over 2600 women. During interviews with the researchers, the women reported what they usually ate. Once the data was collected, the results showed that women, who ate lots of foods that contained folic acid, had much lower rates of breast cancer.

There is no clear-cut, single cause of breast cancer. Many factors are required for the disease to appear. One such factor is estrogen. A recent study showed that women who developed breast cancer tended to have higher levels of estrogen circulating in their bodies than women without breast cancer. This means that women who got their periods before age eleven or entered menopause after age fifty-five have a higher risk of breast cancer. This also supports the theory that the number of menstrual cycles a woman has affects her risk for breast cancer.

Another factor is drinking alcohol. Because alcohol raises estrogen levels, if a woman consumes even moderate amounts of alcohol her risk of breast cancer also is increased. The link between alcohol and breast cancer may even be stronger than other dietary links. However, an important study has discovered that folic acid may uncouple this link.

A very large study of over 34,000 women recently studied the effect of folic acid on the risk of breast cancer. This project was part of the Nurses’ Health Study, an ongoing, long-term study that looks at nutrition’s role in the development of disease. The women in the folic acid and breast cancer study were followed for 12 years. The participants completed detailed food questionnaires that provided the researchers with important data.

The women were divided into four groups:

1.      Women with low folic acid levels and drink alcohol

2.      Women with high folic acid levels and rink alcohol

3.      Women with low folic acid levels and don’t drink alcohol

4.      Women with high folic acid levels and don’t drink alcohol

Within these four groups the women were further divided into subgroups according to the amount of alcohol they consumed each day and their specific folic acid intake.

The researchers found that women who consumed the lowest amounts of folic acid and drank at least one alcoholic beverage a day had the highest rate of breast cancer. In contrast, women who had high intakes of folic acid and also drank at least one alcoholic beverage a day, had the same rate of breast cancer as the women with high folic acid intakes who did not drink. In other words, women who had high levels of folic acid in their diet erased their alcohol-related increase in breast cancer risk.

 

Calcium D-Glucarate

It seems estrogen can be both friend and foe. While women need the hormone to soften skin, thicken hair, and fill out hips and breasts, estrogen can also nourish breast tumors, helping them grow bigger, stronger, and more deadly. Thanks, in part, to good nutrition, American women get their periods early and go through menopause alter in life. Women today also have fewer pregnancies; families with one or two children are quite common.

All of these factors increase the time women’s bodies are exposed to estrogen. As we discussed before, longer exposure means increased opportunities for estrogen to cause trouble. It is also a troubling fact of modern life that we are continuously exposed to cancer-causing chemicals and toxins. These toxins come in part from contaminants in the food we eat and pollutants in the air we breathe.

The body does have a system that eliminates some of the excess estrogen and toxic chemicals before they can cause harm. In the liver, they are bound or attached to a chemical called glucuronic acid. The bound toxin or estrogen is then excreted in bile and eventually eliminated as a waste product in the stool.

However, an enzyme called beta-glucuronidase can break this bond between estrogen and glucuronic acid. When this happens, the hormone or toxin is released from its bone, capable of causing harm once more. Increased beta-glucuronidase activity is associated with an increased risk for various cancers, particularly hormone-dependant cancers like breast cancer.

Fortunately, scientists have discovered that a natural substance found in foods calcium D-glucarate (CDG) can stop the activity of beta-glucuonidase. CDG keeps the harmful estrogen bound to glucuronidase. While CDG is found in fruits and vegetables, the amounts may not be sufficient to maintain effective levels to stop beta-glucuronidase.

CDG has been shown in experimental studies to significantly stop beast cancer growth. And several human trials are currently underway with CDG to determine its capability to decrease the breast cancer risk in women at high risk for the disease.

 

Iodine

There are some very interesting connections between breast tissue and thyroid tissue. Iodine is an essential trace element present in a hormone of the thyroid gland and is involved in several metabolic functions. One iodine function is the protection of breast tissue from cancerous cells.

In a laboratory study, researchers exposed breast cancer cells and breast tissue without any cancer to a type of seaweed that contains high levels of iodine. The seaweed killed all of the cancerous cells, yet did not harm the normal breast cells. Japanese women frequently eat this type of seaweed and have very low rates of breast cancer. The study’s researchers believe one reason for this low incidence of breast cancer may be the iodine in the seaweed.

And, for some as yet unknown reasons, women who have thyroid cancer are at higher risk of developing breast cancer. While they are unsure why this happens, researchers are continuing to study this link, and support of healthy thyroid function remains an important consideration.

 

Broccoli

For quite some time, scientists have observed that cruciferous vegetables, such as broccoli, cabbage, and cauliflower, significantly reduce the risk of disease, including cancer. It seems a phytochemical in broccoli sulforaphane, is one of the chemicals responsible for this beneficial activity. Sulforaphane increases certain enzymes in the body called phase 2 enzymes that deactivate cancer-causing chemicals.

Breast cancer cells exposed to sulforaphane in several lab experiments showed that the compound inhibited the growth of the cancer cells up to 80 percent. Researchers are in the process of setting up clinical trials to study sulforaphane’s effect in women who have breast cancer.

 

Green Tea

There is a tall amount of research, including finding from the Nurses’ Health Study, that suggest green tea beverage consumption is associated with a lower incidence of breast cancer. In fact, researchers have long noted the low rates of breast cancer in Japan, a country where green tea consumption is very high.

The active compound in green tea responsible for breast cancer inhibition is epigallocatechin-3 gallate or EGCG. When breast cancer cells are exposed to EGCG in lab experiments, the cells stop growing, lose their ability to replicate, and die.

In a recent study, researchers discovered that drinking green tea prevented the recurrence of breast cancer in women who have previously been diagnosed and treated for the disease. This study involved over 1100 Japanese women. The women who drank green tea every day had very low rates of their breast cancer returning.

 

Maitake Mushrooms

For thousands of years, maitake mushrooms have been linked to good health in those who eat them. Called “dancing mushrooms” (possibly due to their wavy, rippling appearance or possibly due to the little dance of joy mushroom hunters perform when they find them in the woods), maitakes contain an important compound called D-fraction.

Not only does the D-fraction in maitake mushrooms stop the growth of cancerous tumors, it also alerts and stimulates immune cells (including macrophages and natural killer cells) to fight the disease. Maitake also inhibits some of the mechanism that promotes metastasis, or spread, of cancer cells in the lymph and bloodstream.

Because of this success, maitake is now being used in clinical trials of women with breast cancer. One study reported significant improvement of symptoms, including reduction of the tumor. The maitake was given to breast cancer patients in addition to standard chemotherapy.

 

Q. Should these nutrients be used in place of traditional treatment for breast cancer?

A. Absolutely not. None of these nutrients can cure breast cancer. However, they can be a part of a validated plan of treatment. If you have breast cancer, talk to your health care practitioner about these nutrients. Remember, nutritional supplements are just that: supplements to food, medication, and treatment. They are intended to enhance and prevent, not replace.

 

Conclusion

Despite apprehension in performing self-breast exams, women are very proactive in their health. Yearly mammograms and pap tests have been an important part of their lives for many years, and newer and more accurate diagnoses are emerging. The prevention of health problems in themselves and their families has always been a high priority for women. And for women, nutrition has played an important part of health problem prevention.

Nutritionally speaking, what benefits your breasts benefit your whole body. However, as we have learned, there are specific links between nutrition and developing breast cancer that seem to be fairly strong.

Making a few changes may reduce the risk of developing the disease. The nutrients listed here, vitamin B12, folic acid, calcium d-glucarate, iodine, broccoli, green tea, and maitake mushrooms can be an important part of a woman’s preventative health regimen.



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Turmeric and Alzheimer’s Disease
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Date: May 10, 2007 12:38 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Turmeric and Alzheimer’s Disease

Turmeric and Alzheimer’s Disease

 

In India, Alzheimer’s disease is relatively uncommon. People over the age of 65 living in certain rural areas of India have a less than 1 percent (0.84) chance of developing the disease. In the larger cities and rural areas of India, the risk is just 2.4 percent.

Compare these findings to people over the age of 65 living in the United States. Again, depending on where we are living, our chances of developing Alzheimer’s disease range from a little under 5 percent to an astonishing 17 percent.

So what are people who are living in India doing that we aren’t doing here in the US to account for these dramatic differences? The answer seems to be curry, that zesty spice and staple of Indian foods. Research has shown that a compound in curry not only prevents changes in the brain that lead to Alzheimer’s disease; it actually reverses some of the damage already present.

 

Q. How can curry prevent these changes in the brain? Isn’t that a lot to expect from a spice?

A. Evidently, it’s not too much to expect from this spice. Curry comes from the turmeric plant – Curcuma longa is the plant’s official name. Curcumin, a plant compound in turmeric, is the source of curry’s instantly recognizable bright yellow pigment. When it comes to the scientific research of Curcuma longa, the terms curcumin and turmeric are both used. Both refer to the same thing- tumeric extract.

There have been more than 1300 studies on tumeric and its health benefits for humans. Research has shown tumeric is able to help the body get rid of cancer-causing toxins. Turmeric also blocks estrogen receptors and enzymes that promote cancer. And it’s been found to stop the growth of new blood vessels in cancerous tumors – an important factor in keeping cancer from getting larger and spreading throughout the body.

But one of turmeric’s most exciting health benefits is its ability to reduce, prevent, and stop inflammation. While inflammation is a normal and needed response to injury or disease, chronic inflammation can cause damage to tissues. And researchers are now finding inflammation plays a huge role in Alzheimer’s disease.

 

Q. I’ve always heard that Alzheimer’s disease was caused by complex growths in the brain called plaques and tangles. How can simple inflammation cause such a devastating disease?

A. You are right. Plaques and tangles are indeed the hallmarks of Alzheimer’s disease. But researchers looking at the brain damage caused by Alzheimer’s have always noted the presence of inflammation wherever plaques and tangles form. In the past, this inflammation was thought to be simply a consequence of Alzheimer’s disease. Now scientists believe the inflammation itself starts a chain reaction ultimately contributing to the development of Alzheimer’s disease.

` When cells in the brain are disrupted by inflammation, amyloid, and a protein normally found in the brain, beings to act chaotically. This chaos results in the creation of beta-amyloid, protein that is toxic to cells in the brain. Sticky deposits of beta0amyloid build up and collect around the cells, making dense clumps or plaques. Because the brain can’t break the plaques down and get rid of them, they stay right where they are and slowly accumulate.

Tangles result when long protein fibers that act like scaffolding for brain cells begin to twist and tangle. The cell is damaged and eventually dies. But the tangled proteins remain in the brain even after the dead neuron has been cleared away. And inflammation might be the culprit causing the long protein fibers to start tangling.

The consequence of these abnormalities of protein in the brain is more than the cell death they cause. They also act as roadblocks interfering with electrochemical messengers being shot from cell to cell. Therefore, the remaining healthy cells’ activity is diminished as well.

Research of identical twins has repeatedly shown that if one twin has Alzheimer’s disease, the other has a 60% chance of developing the disease, too. Scientists from the Karolinska Institute in Stockholm, Sweden, looked at information from 20,000 twins collected in the 1960s and found 109 pairs of siblings where only one twin had been diagnosed with Alzheimer’s. When the Swedish researchers analyzed data about the twin’s health, they found the twin with Alzheimer’s disease almost always had chronic gum disease. While bleeding gums are definitely not he cause of Alzheimer’s disease, the inflammation that plays a large part of chronic gum disease may signal an inflammatory process stuck in overdrive.

In fact, the inflammatory process might occur years before the onset of Alzheimer’s, and be the result of any number of infections people can contract. That’s why current research is searching for ways to protect brain cells from inflammation. And why some countries have low rates of Alzheimer’s disease, like India.

 

Q. Why curry? Couldn’t other lifestyle difference account for the low rates of Alzheimer’s disease in India?

A. That’s a good question. When researchers begin studying a disease, like Alzheimer’s, they look for trends to help them determine how and why the disease occurs. For example, we all now know the connection between cigarettes smoking and long cancer. But, it wasn’t until the 1930’s that doctors noticed the trend fro cigarette smokers to have more lung cancer than people who didn’t smoke.

So it has been with researchers studying Alzheimer’s disease. They know Alzheimer’s disease has an important connection to inflammation. They also know turmeric reduces inflammation. And when researchers noticed these trends – that people in India eat high amounts of curry from turmeric and have very little Alzheimer’s disease – they began to theorize that turmeric might be able to prevent or even treat the illness. And the research they designed around these trends has unequivocally found turmeric to be on common denominator.

 

Q. What have the turmeric studies shown so far?

A. Simply amazing findings are coming from curry research. Not only does turmeric slow down cancer growth, it’s also been found to correct the cystic fibrosis defect in mice, help prevent the onset of alcoholic liver disease, and may slow down other serious brain diseases like multiple sclerosis.

Researchers from the University of California Los Angeles (UCLA) studying turmeric have found it to be more effective than the drugs currently being investigated for Alzheimer’s disease treatment and prevention. The researchers have discovered the actual structure and shape of turmeric allows it to penetrate the blood-brain barrier effectively and bind to beta amyloid that’s already built up in the neurons. Turmeric helps maintain healthy brain cellular metabolism, helps the cells repair themselves, and keeps the cells connected to each other. In other words, turmeric helps brain cells stay healthy.

And now the UCLA Alzheimer’s Disease Research Center (ADRC) is using turmeric in clinical trials and studying the effect of this powerful spice in patients diagnosed with this devastating disease. Clinical trials are the gold standard of medical research. But it’s rare in Alzheimer’s disease. And it’s even more rare when all-natural herbs and spices like turmeric are used in hopes the positive benefits will be discovered. The head of the UCLA’s research team was recently interviewed and stated that setting out to hopefully prove turmeric’s ability to prevent and treat Alzheimer’s disease was “tremendously exciting.”

 

Q. I recently read that one of the non-steroidal anti-inflammatory drugs (NSAID) was found to prevent Alzheimer’s disease. Is this true?

A. Scientists recently studied ibuprofen, one of the NSAIDs investigated for Alzheimer’s disease Prevention. Ibuprofen belongs to a family of drugs that includes naproxen, indomethacin, nabumetone, and several others. These drugs are used most often to get rid of headaches, mild arthritis, and other kinds of pain and inflammation.

In the studies, the average dose of ibuprofen was 800mg a day. Patients took the product for two years. While the results suggested that ibuprofen might reduce the risk of developing Alzheimer’s, ibuprofen’s side effects are too harmful to be a valid lifelong prevent aid treatment. Ibuprofen, like other NSAIDs, can cause gastrointestinal bleeding when used at high dosages over a long period of time. Long term use of ibuprofen can also lead to analgesic nephropathy, a kind of kidney damage caused by NSAIDs.

As we discussed earlier, turmeric appears to block and break up brain plaques that cause the disease and helps reverse some of the damage already present. Ibuprofen does not provide any protection against free radical damage. No anti-inflammatory medicine can do this.

 

Q. If I eat curry will I be protected against Alzheimer’s disease? There aren’t many foods or recipes I make that require curry, do I need to eat it every day? And how much do I need?

A. If you enjoy Indian cuisine, by all means, enjoy these delicious foods. You’ll benefit your brain and your appetite. But you make a good point, American meals rarely contain curry. That’s why supplements that contain extracts are suddenly quite popular. In fact, there are numerous turmeric/curcumin supplements on the market today.

But like all nutritional supplements, some turmeric supplements are superior to others. You need to read their labels to make sure the turmeric extract you are buying will provide the protection you need. Look for high-potency turmeric extract from turmeric (Curcuma longa) rhizome. And make sure the extract is standardized to contain 90% curcuminoids, the active ingredient in turmeric responsible for the positive research findings.

 

Conclusion

Researchers once thought that preventing for Alzheimer’s disease would elude them for decades. In fact, several scientists privately speculated the disease might never be ameliorated. They thought the origin of the disease was too complex and the symptoms of the disease were too profound.

That’s why ongoing research on turmeric is so exciting. A safe, natural, and effective way to protect against Alzheimer’s disease almost seems too good to be true. But, the nation of India and its low incidence of Alzheimer’s disease are proof these are not just fluke findings – making turmeric extract a supplement to remember.

 



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Learn about Bone Health!
TopPreviousNext

Date: April 20, 2007 12:43 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Learn about Bone Health!

Bone Health

Approximately 44 million American women and men aged 50 and older have osteoporosis (severe bone loss) or osteopenia (mild bone loss), with women being affected about twice as often as men. At least 1.5 million fractures of the hip, vertebra (back or neck), or wrist occur each year in the United States as a result of osteoporosis, and the annual cost of treating this disorder is nearly $14 billion and rising. Unfortunately, the toll in human suffering and loss of independence is even greater.

In this issue of Ask the Doctor, we will discuss the risk factors for osteoporosis and some key nutrients you can add to your diet that can minimize bone loss and reduce your chances of developing this disease.

Q. What are the risk factors for osteoporosis?

A. Small body frame, underweight, Caucasian or Asian race, a sedentary lifestyle, cigarette smoking, excessive alcohol or caffeine intake, high intake of carbonated beverages (especially colas), and having other family members with osteoporosis all increase personal risk of developing the disease. Certain medical conditions, including diabetes, celiac disease, hyperthyroidism, rheumatoid arthritis, chronic obstructive lung disease, hyperadrenalism, and hyperparathyroidism, are all associated with an increased risk of osteoporosis. Some medications increase the rate at which bone is lost; these include drugs prescribed for the treatment of seizures, drugs used for blood thinning, steroids such as prednisone, aluminum-containing antacids, and loop diuretics (furosemide {Lasix}).

Q. Isn’t bone loss just a normal consequence of aging?

A. Although bone mass normally declines after the age of 35, bone loss severe enough to cause fractures after just minor trauma (such as bump or fall) seems to be a relatively new phenomenon. Osteoporosis was rare in the late 19th century, and it was not until around 1920 that the condition began to attract attention among doctors. Since that time, the percentage of people who develop osteoporosis has continued to increase. For example, the age-adjusted prevalence of osteoporosis in England and Sweden double between 1950 and 1980. In addition, the percentage of elderly people with osteoporosis in some developing countries is lower than that of elderly Americans, despite lower calcium intakes in the developing countries, further suggesting that osteoporosis is a disease of modern civilization.

Q. Can osteoporosis be prevented?

A. Engaging in regular weight bearing exercise, avoiding excessive consumption of alcohol and caffeine, and quitting smoking will slow the rate of bone loss. Eating adequate, but not excessive, amounts of protein also enhances bone health. In addition, a growing body of research has shown that supplementing with various vitamins and minerals may not only help prevent, but in some cases actually reverse, bone loss. At least 15 different nutrients have been found to play a role in bone health.

Q. What type of calcium is best?

A. For most people, calcium salts are absorbed about the same, between 30% and 40% of the administered dose. People who low stomach acid (hypochlorhydria) should not use calcium carbonate, because that form of calcium is absorbed poorly in the absence of stomach acid. Calcium phosphate may be preferable for many older people, because phosphorus is necessary for normal bone formation, the phosphorus intake of older people is often low, and calcium supplements inhibit the absorption of phosphorus.

Also, calcium bound to phosphorus is the form in which calcium in the bone is stored, and it has a much greater bone activity than other forms.

Q. How much vitamin D is needed to promote strong bones?

A. Because vitamin D is produced when the ultraviolet rays from the sun hit skin, people who stay out of the sun, wear sunscreen, or live in a northern latitude (such as Boston or Seattle) where less ultraviolet light reaches the skin, are at increased risk of vitamin D deficiency. In addition, aging decreases a person’s ability to synthesize vitamin D in the skin. Results from five research trials on vitamin D found that supplementation with 700-800 IU of vitamin D per day decreased the number of hip fractures by 26%, but 400 IU per day was ineffective. In addition to enhancing bone health, vitamin D improves nerve and muscle function in older people, thereby reducing their chances of falling down. Supplementation of elderly women with 800 IU of vitamin D per day has been shown to decrease the number of falls by about 50%.

Q. Is that much vitamin D safe?

A. The Food and Nutrition Board of the Institute of Medicine established a “safe upper limit” of 2,000 IU per day in 1997. More recent research suggests that up to 4,000 IU of vitamin D per day is safe for the average person. However, you likely don’t need nearly this much to address most bone issues.

Q. Why would nutrients besides calcium and vitamin D is important?

A. Bone is living tissue, constantly remodeling itself and engaging in numerous biological functions. Like other tissues in the body, bone has a wide range of nutritional needs. The typical refined and processed American diet has been depleted of many different vitamins and minerals, some of which play a key role in promoting bone health. Not getting enough of one or more of these micronutrients may be and important contributing factor to the modern epidemic of osteoporosis. In addition, supplementing with calcium may cause a loss of magnesium, zinc, silicon, manganese, and phosphorus, unless these nutrients are also provided.

Q. What nutrients besides calcium and vitamin D promote healthy bones?

A. Magnesium, zinc, copper, manganese, vitamin K, boron, strontium, silicon, folic acid, vitamin B6, vitamin B12, phosphorus, and vitamin C have all been shown to play a role in bone health. Following is a brief description of the role that each of these 15 nutrients play in building healthy bones.

Calcium: A component of the mineral crystals that make up bone.

Vitamin D: Enhances calcium absorption, prevents falls by improving nerve and muscle function.

Magnesium: Important for bone mineralization (accumulation of minerals which form bones). Magnesium deficiency is associated with abnormal bone mineral crystals in humans. In an open clinical trial, magnesium supplementation increased bone mineral density by an average 5% after 1-2 years in postmenopausal women.

Copper: Laboratory research has found that copper promotes bone mineralization and decreases bone loss, and that osteoporosis can develop if the diet is deficient in copper. Western diets often contain less copper than the amount recommended by the National Academy of Sciences. In a 2-year double-blind trail, copper supplementation reduced bone loss by 90% in middle-aged women, compared with a placebo.

Zinc: Like magnesium, zinc is important for bone mineralization, and also has been shown to decrease bone loss. Low dietary zinc intake was associated with increased fracture risk in a study of middle-aged and elderly men. The zinc content of the diet is frequently low; a study of elderly low-income people found they were consuming only half the Recommended Dietary Allowance for this mineral.

Manganese: Plays a role in the creation of the connective-tissue components of bone. Manganese deficiency in laboratory tests resulted in low bone mineral density and weak bones. Manganese deficiency may be associated with the development of osteoporosis.

Boron: Supports creation of bone-protecting hormones such as estrogen, testosterone, and DHEA. Boron supplementation prevented bone loss in experimental studies. In human volunteers consuming a low-boron diet, boron supplementation decreased urinary calcium excretion by 25-33%, a change that may indicate reduced bone loss.

Silicon: Plays a role in the synthesis of the connective-tissue components of bone. Silicon deficiency has been associated with bone abnormalities. In an observational study, higher dietary silicon intake correlated with higher bone mineral density. In a clinical trial, administration of an organic silicon compound increased bone mineral density of the femur (or thigh bone) in postmenopausal women.

B vitamins (folic acid, vitamin B6, and vitamin B12): These three B vitamins have been shown to lower blood levels of homocysteine, a breakdown product of the amino acid methionine. An elevated homocysteine concentration is a strong and independent risk factor for fractures in older men and women. Homocysteine levels increase around the time of menopause, which may explain in part why bone loss accelerates at that time. In a 2-year double-blind trial, supplementation of elderly stroke patients with folic acid and vitamin B12 reduced the number of hip fractures by 78%, compared with a placebo.

Strontium: This trace mineral is incorporated into bone and appears to increase bone strength. It also stimulates bone formation and inhibits bone breakdown. Controlled trials have demonstrated that strontium supplementation of postmenopausal women increases bone mineral density and decreases fracture risk.

Vitamin K: Best known for its effect on blood clotting, vitamin K is also required for the creation of osteocalcin, a unique protein found in bone that participates in the mineralization process. The amount of vitamin K needed for optimal bone health appears to be greater than the amount needed to prevent bleeding. Vitamin K levels tend to be low in people with osteoporosis. In randomized clinical trials, supplementation of postmenopausal women with vitamin K prevented bone loss and reduced the incidence of fractures.

Q. Which form of vitamin K is best?

A. Two forms of vitamin K compounds are present in food: vitamin K1 and vitamin K2. Vitamin K1 (also called phylloquinone) is present in leafy green vegetables and some vegetable oils, and vitamin K2 is found in much smaller amounts in meat, cheese, eggs, and natto (fermented soybeans).

To make things a little more complicated, Vitamin K2 itself can occur in more than one form. The two most important to this discussion are menaquinine-4 (MK-4, also called menatetrenone), which is licensed as a prescription drug in Japan, and menaquinone-7 (MK-7), which is extracted from natto.

Research suggests that MK-7 from natto may be an ideal form of vitamin K. The biological activity of MK-7 in laboratory studies was 17 times higher than that of vitamin K1 and 130 times higher than that of MK-4. After oral administration, MK-7 was better absorbed and persisted in the body longer, compared with MK-4 and vitamin K1. Although both have shown ability to prevent osteoporosis in laboratory research, a much lower dosage (600 times lower) of MK-7 is required, compared to MK-4, to obtain beneficial effects.

Thus, MK-7 has greater biological activity, greater bioavailability, and possibly more potent effects on bone, compared with other forms of vitamin K. The potential value of MK-7 for bone health is supported by an observational study from Japan, in which increasing natto consumption was associated with a lower risk of hip fracture. While additional research needs to be done, the available evidence suggests that the best forms of vitamin K for long-term use at physiological doses are MK-7 and vitamin K1.

Q. Why is strontium so important in building strong bones?

A. Strontium is of great interest to bone health researchers and has been studied in very high doses. Surprisingly, lower doses are not only safer for long-term supplementation, but may in fact have a greater impact on bone health than very high doses. Too little, and bone density is impaired; too much and health may be impaired. This is a case where dosing needs to be just right for optimal impact. Therefore, until more is known, it is wise to keep supplemental strontium at less than 6 mg per day.

Q. Can people taking osteoporosis medications also take bone-building nutrients?

A. Because nutrients work by a different mechanism than osteoporosis drugs, nutritional supplements are likely to enhance the beneficial effect of these medications. Calcium or other minerals may interfere with the absorption of biphophonates such as alendronate (Fosamax) or etidronate (Didronel). For that reason, calcium and other minerals should be taken at least two hours before or two hours after these medications. Also, it is always best to discuss the supplements you are using with your healthcare practitioner to create an integrated health plan.

Final thoughts…

Bone health ramifications extend beyond osteoporosis and fractures. Bone health is essential for freedom of movement, safety, comfort, independence and longevity. Weak bones do not heal well – sometimes they never heal at all. Osteoporosis-related fractures rob us of our mobility and consign thousands of Americans to walkers and wheelchairs every year. In fact, 40% of people are unable to walk independently after a hip fracture, and 60% still require assistance a year later. The most terrible consequence of fractures related to osteoporosis is mortality. The impairment of the ability to move around freely can cause pneumonia and skin damage leading to serious infections. It is estimated that suffering a hip fracture increases the risk of dying almost 25%. Making bone health a priority now will allow you to reap health dividends for many years to come.



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Complete Liver Cleanse
TopPreviousNext

Date: April 19, 2007 04:17 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Complete Liver Cleanse

Complete Liver Cleanse

Technical Data Sheet

 

DESCRIPTION:

The liver performs over 500 functions, including metabolizing carbohydrates and proteins, synthesizing and storing vitamins, and regulating hormones – naming just a few. To do this job, the liver is also required to be exposed to potentially harmful toxins and chemicals, every day.

One way to support the liver is through periodic supplementation with the proper balance of herbal ingredients, phytosterols, and fiber. Complete Liver Cleanse is a convenient, multi-ingredient formula that supports overall liver health and detoxification.

Complete Liver Cleanse:

Includes ingredients for various aspects of liver and gallbladder support:

-Herbal ingredients that support liver and gallbladder health

-Detoxifying ingredients that keep bound toxins from being reabsorbed

-Phytosterols to block cholesterol absorption in the intestines

-Fiber that moves cholesterol and toxins out of the body

-Oat beta-glucan fiber with up to 4 times higher viscosity than other beta-glucan

Fibers

-Simple, two week liver cleanse program

FORMULA:

Each 3 capsules contain:

Calcium (as calcium D-glucarate) 13 mg

Proprietary PuraFiber Blend: 1 mg

Viscofiber Oat B-Gucan Concentrate, phytosterols

(beta sitosterol, campesterol, stigmasterol, brassicasterol,

and other plant sterols), and glucomannan

Milk Thistle (Silybum marianum) Fruit Phytosome 220 mg

One part Milk Thistle Extract, standardized to contain 80%

Silymarin bound to two parts phosphatidylcholine (soy) using

a patented process

Burdock (Arctium lappa) Root Extract 4:1 100 mg

Calcium D-Glucarate 100 mg

Boldo (Peumus boldus) Leaf Extract 2:1 75 mg

Turmeric (Curcuma longa) Rhizome Extract 50 mg

Standardized to contain 90% curcuminoids

Dandelion (Taraxacum offinale) Root Extract 4:1 50 mg

Artichoke (Cynara scolymus) Leaf Extract 30 mg

Standardized to contain 13-18% caffeylquinic

Acids calculated as chlorogenic acid

Contains no: sugar, salt, yeast, wheat, dairy products, artificial coloring, artificial flavoring, ingredients of animal origin, or preservatives. This product contains natural ingredients; color variations are normal.

Other ingredients: See label for most current information

Viscofiber is a registered trademark of Cebena Bioproducts, Inc. The use and composition of the Viscofiber proprietary formula is protected by patients and patent applications filed in the U.S., Canada and internationally.

This product contains calcium D-glucarate, the use of which is licensed from Applied Food Sciences, LLC, and protected by U.S. patent 4,845,123.

HOW DOES IT WORK?

The Liver

Every day, the liver must process an almost unbelievable amount of blood – at a rate of three pints every minute. All the while, the liver performs over 500 physiologic functions, including protein and glucose synthesis, carbohydrate metabolism, vitamin and mineral storage, synthesis of clotting factors, urea formation, metabolism of medications, and the production of bile. The liver also assists in hormonal regulation, blood glucose control, and other regulatory functions.

Harmful substances that have been neutralized by the liver are carried to the intestines and kidneys for excretion. They are transported by bile, a greenish, watery solution that is synthesized, and continuously being excreted, by the liver. Stored in the gallbladder, a small sac cupped in the under surface of the liver, bile is also required for the digestion of dietary fats. However, in the case of toxins, bile is primarily an early transporter of the toxic compounds to the intestines, where they can be bound to fiber that helps transport them out of the body. Environmental toxins, including lipid (fat) soluble toxins, are broken into water-soluble components by bile to be excreted through the kidneys or colon.

Liver Detoxification

Detoxification refers to the process of excreting potentially harmful compounds that are both generated by the body and acquired through exposure to the environment. In the body, toxins are generated as by-products of cellular metabolic processes. Examples include dead and digested bacteria, hydrogen peroxide, cellular debris, and carbon dioxide.

The Environmental Protection Agency has determined that the amount of environmental toxins in the air, groundwater, and soil has increased significantly in the last 40 years. In fact, the use of pesticides has doubled every ten years since 1945. Americans are increasingly exposed to heavy metals, pesticides, fossil fuel emissions, sulfur oxides, hydrocarbons, and other harmful chemicals. The Environmental Protection Agency reports that traces of toxic chemicals can now be found in nearly every American.

Herbal Liver Support

One of the major components in Complete Liver Cleanse is its milk thistle extract, standardized to contain 80% silymarin, the plant’s most bioactive compound. Milk Thistle provides support, at a cellular level, for healthy liver function. A patented delivery system, known as the Phytosome process, provides superior absorption of the milk thistle extract.

Silymarin, a key compound found in milk thistle, is a mixture of flavonoids with a long history of liver support. Silymarin supports the health of Kupffer cells, specialized liver cells responsible for removing bacteria, old blood cells, and other foreign matter from the liver’s blood supply. Silymarin scavenges free radicals (superoxide anion radical and nitric oxide) produced by activated Kupffer cells, supports healthy leukotriene levels, and supports glutathione production that is used in detoxification.

Silymarin also supports the health of hepatocytes, highly versatile liver cells with unique physiologic functions. Studies of silymarin have demonstrated that it supports the health of the hepatocyte outer membrane, which is crucial to the liver’s detoxification processes. Silymarin also supports the healthy regenerative ability of the liver through support of protein synthesis in the hepatocytes.

Phytosome Process

A special, patented proves known as Phytosome enhances the absorption of milk thistle in Complete Liver Cleanse. The Phytosome process pairs herbal ingredients with phosphatidylcholine molecules. Phosphatidylcholine is a naturally occurring substance found in soybeans, egg yolks, and some vegetables. In the body, phosphatidylcholine is an important building block of cell membranes.

When milk thistle (or other herbs) are bound with phosphatidylcholine, the phosphatidylcholine molecule facilitates absorption through the intestines into the bloodstream. Research has shown increased blood and serum levels for phytosome herbs in comparison to the individual herb alone.

To test whether binding an herb with phosphatidylcholine increased its bioavailability, researchers gave volunteers identical amounts of either milk thistle alone, or milk thistle phytosome. The researchers then took blood sample from the participants and measured the level of silybin (a key compound in milk thistle). The measurements showed that silybin levels in participants taking the phytosome form of milk thistle were higher, and that silybin was detected for a longer time, than those who took milk thistle without the phytosome delivery system.

Other Herbal Liver Supportive Ingredients

Herbal extracts are often at their best when they are working synergistically – that is, when different constituents of each plant work together and support each other. Complete Liver Cleanse contains a variety of herbal extracts that have noted benefits for supporting the body’s healthy bile flow and free-radical scavenging effects. These ingredients provide a wide spectrum of liver supportive benefits.

For instance, dandelion root extract supports healthy bile flow from the gallbladder.

Burdock Root:

Burdock is originally native to Europe and Asia, but was introduced to North America, probably during colonial times. The plant is commonly found in the northern United States, and is very recognizable, with large, heart-shaped leaves. It has a long history of traditional use for gastrointestinal support.

Burdock root (Arctium lappa) supports the natural physiologic processes of organs involved in detoxification and elimination: notably, the liver, kidneys, and intestines.

Boldo:

Bolodo (pemus boldus) is a small evergreen native to South America, but naturalized to southern Europe. The leaves are considered the health supportive part of the plant. This herb has a long history of use in Chile, and became known in Western countries in the late 19th century.

In scientific studies, boldo appears to have strong free-radical scavenging ability, mostly attributed to the catechin and flavonoids content of its leaves. In a clinical study, boldo also appears to relax smooth muscle and support intestinal transit time.

Artichoke Leaf extract specifically supports healthy bile production in the liver and healthy gastrointestinal function in general. Research into artichoke’s gastrointestinal supportive properties has included at least three clinical trials. Artichoke’s role in supporting healthy cholesterol levels within normal limits has also been investigated.

Turmeric:

Turmeric (Curcuma longa) is a perennial shrub native to southern Asia with a long history as both a food ingredient and for health support.

More recently, turmeric has been investigated for its support of healthy bile secretion, and pancreatic and gastric function.

In a scientific study, dietary curcuminoids derived from turmeric supported healthy lipid metabolism and cholesterol levels already within normal limits.

Curcumin has also been shown in scientific studies to enhance the activity of glutathione S-transferase - an enzyme responsible for linking glutathione (one of the body’s natural antioxidants) with toxins to help remove them from the body. In this way, it provides additional support for healthy liver function.

Detoxification

Calcium d-glucarate:

The process of detoxification is the breakdown and excretion of substances that are no longer needed or may be harmful to the body. One of the ways in which the body excretes hormones and toxins is by binding them to glucuronic acid in the liver, and then excreting this compound in the bile.

However, this process can be disrupted by B-glucuronidase, an enzyme that is produced by intestinal bacteria. This enzyme has the ability to break (uncouple) the chemical bond established by glucuronic acid. This action releases the bound toxins, which are then reabsorbed into the body instead of being excreted.

Calcium D-Glucarate is the calcium salt of d-glucaric acid. It is found in both the human body, and in some plant sources, including broccoli and oranges.

Calcium d0glucarate enhances the body’s detoxification systems by inhibiting the actions of beta-glucuronidase. This helps decrease the portion of active compounds that could be hazardous to the body.

Phytosterols

Cholesterol is a waxy, fat-like substance that is vital to fat digestion, cell structure, nerve insulation and hormone production. Cholesterol comes from two sources: dietary or “exogenous” cholesterol absorbed in the intestine, and “endogenous” cholesterol formed mostly by the liver and stored in the gallbladder.

Cholesterol occurs in two forms known as lipoproteins. Lipoproteins act as transports that carry fat s to and from the cells.

High-density lipoprotein (HDL) carries low lipid density cholesterol (LDL) away from arterial walls and returns it to the bloodstream. LDL then travels back to the liver, which processes and eliminates it. While high levels of HDL cholesterol is desirable, high amounts of LDL cholesterol is not supportive of optimal health.

LDL-cholesterol is both synthesized in the body, or absorbed into the bloodstream through receptor sites in the intestines. Think of these receptors as “parking spaces” for cholesterol. As it happens, the liver can receive up to 500 mg per day of cholesterol from intestinal absorption. (It can also produce as much as 1000 mg per day).

One way to help reduce the absorption of LDL cholesterol molecules it to occupy their “parking places” in the intestines. Phytosterols in Liver Cleanse are essentially the “fat” of plants. They’re found in nuts, corn and rice and are some of the “good” fats associated with the benefits of olive oil, flaxseed oil and other healthy oils.

The structure of phytosterols is so similar to cholesterol that they fit perfectly in the specially-shaped intestinal parking spaces that LDL-cholesterol would normally occupy.

Taken with, or just before meals, phytosterols block the cholesterol receptor sites so that cholesterol is excreted from the body rather than absorbed. Phytosterols also have the additional role of helping promote healthy bile salt excretion in the intestines.

The phytosterol blend in Complete Liver Cleanse can help minimize the absorption of cholesterol from high-protein food sources, help retain healthy cholesterol levels that are within normal limits, and move bile sat through the digestive system.

Fiber and detoxification

Fiber plays a key role in the removal and excretion of intestinal toxins in detoxification. Only fibers that can effectively bind toxins will be successful in eliminating these harmful substances. Due to the unique benefits of individual fibers, the best binding, removal, and elimination effects are noted when combining different fiber types. Complete Liver Cleanse contains a combination of oat beta-glucan and konjac fiber that has been shown in scientific studies to bind to bile salts.

Dietary fibers are complex mixtures of cellulose, hemicellulose, pectin, mucilage, and gums, which are resistant to digestive fluids or enzymes – that is, they aren’t absorbed into the bloodstream. So, while fiber itself doesn’t necessarily provide nutrients, it does promote laxation and modulate gastric and intestinal physiology. Intestinal flora that normally reside within the colon utilize fiber as a medium for microbial fermentation, resulting in the synthesis of the vitamins, vitamin K and biotin, and the formation of short chain fatty acids, or SCFA.

SCFA have a simple, but important job: to be absorbed by the colon mucosa, increasing fecal matter bulk and providing energy. Fiber has been demonstrated in numerous clinical studies to provide support of gastrointestinal, cardiovascular, immune, and endocrine function health.

Complete Liver Cleanse also features two unique fibers to promote detoxification – konjac and oat beta-glucan.

Konjac:

Konjac, (Amorphophallus Konjac) is a tuber native to Asia, rich in glucomannan polysaccharide. This viscous material is made into a jelly, noodles and other foods. It has been used in Japan for at least a thousand years.

As a fiber, konjac has shown positive results maintaining healthy cholesterol levels within normal limits in clinical studies. This beneficial effect is due to konjac’s ability to boost excretion of bile acid.

Oat beta-glucan:

Oat beta-glucan has been a widely studied fiber source for supporting healthy cholesterol levels within normal limits.

In a randomized clinical study, oat beta-glucan showed support of healthy HDL/LDL ratios already within normal limits in individuals over a three week trial.

Closely linked to cholesterol, oat beta-glucan has also been studied for its support of healthy bile excretion.

Fiber has benefits beyond maintaining healthy cholesterol levels already within normal limits. It also contributes to healthy blood sugar levels already within normal limits. In a double-blind, clinical study, the oat beta-glucan fiber used in Liver Cleanse was shown to have 4 times higher viscosity than another high concentrate beta-glucan fiber.

Viscosity – the resistance to flow – is an important factor in beta-glucan, and all fiber. Water, for instance, would have a low viscosity, because it provides very little resistance to movement. Fiber, on the other hand, should have a higher viscosity in order to maximize its transit time through the GI tract, providing a gentle “scrubbing” on the intestinal walls. Therefore, the higher the viscosity, the greater the potential benefit.

RECOMMENDATIONS:

Three capsules in the morning and three capsules at bedtime for 14 days.

LABEL PRECAUTION:

Warnings: Do not use if you know or suspect you have an obstructed bile duct or problematic gallstones. If pregnant, nursing or taking prescription drugs, consult your healthcare practitioner prior to use. Keep out of reach of children.



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D-Ribose Powder Benefits!
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Date: April 10, 2007 11:57 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: D-Ribose Powder Benefits!

Benefits

Supports normal heart function*

A significant amount of in vitro, animal and human research suggests benefits of ribose on heart function.* Studies have shown that ribose supplementation can enhance cardiac energy levels and support cardiovascular metabolism.* Ribose has been shown in clinical trials to enhance the recovery of heart muscle ATP levels and improve myocardial function following exercise.

Studies suggest that ribose supplementation can increase the tolerability of the cardiovascular system to exercise-induced fatigue.1 In one study, twenty men underwent treadmill exercise tests on two consecutive days to confirm the onset of fatigue secondary to exercise. The participants were then randomized to the treatment group or a placebo group. The groups received either four doses of 15 grams of D-ribose (60 grams/day total) or the same amount of placebo each day. After three days of treatment, another treadmill test was performed. The time it took to reach the specified level of fatigue was significantly greater in the ribose group than in the placebo group.

Another study investigated the ability of ribose to support healthy heart function and quality of life.2 In a randomized, crossover design study, fifteen individuals were given 5 grams three times a day of either D-ribose or placebo. Each treatment period lasted three weeks. In patients receiving ribose, echocardiography demonstrated enhancement of heart function, reflecting a “more efficient relaxation phase of the heart”. Participants also had a significant improvement in their subjective quality of life scores compared to placebo.  

Scientists suggest that suboptimal heart function is a result of the heart requiring more energy to function properly. Ribose supports the heart’s enhanced energy requirements, promoting optimal heart function. It does so by enhancing the stores of high-energy phosphates in heart tissue. These intermediates are necessary for the production and resynthesis of ATP. A double-blind crossover study in which 12 individuals were randomized to receive either ribose or dextrose (both administered as 5 grams three times daily for three weeks, followed by a 1-week washout period and crossover of treatments for three additional weeks) suggested significant enhancements in normal cardiac function during the period of ribose supplementation.3

Perhaps one of the more useful illustrations of the potential for ribose to support heart function comes from a study in which 20 rats received a continuous infusion of ribose for 24 hours (control rats received an infusion of saline). The hearts were then explanted (as they would be for heart transplants) and placed in preservation solution that was enriched with ribose for 4 hours. ATP levels were measured from tissue biopsies and revealed that 10 of the ribose-treated hearts had ATP levels higher than 12.3 micromoles per gram whereas saline-treated hearts (controls) had lower ATP levels, with 20% showing levels below 10 micromoles per gram of tissue. This provides support for the hypothesis that ribose may enhance the preservation of ATP levels in cardiac tissue, promoting normal heart function.4

Further animal studies have shown that ribose significantly enhances heart function after experimentally induced cardiac depression. Rats were injected with isoproterenol (a drug that stimulates sympathetic nervous system function) and had their abdominal aorta constricted to induce depression of heart function and reduce cardiac ATP levels. The decrease in ATP was primarily responsible for the depression of heart function. Continuous infusion of ribose for 24 hours replenished ATP concentrations to normal levels and normalized heart function in these animals.5

Ribose may strengthen and support the body’s crucial antioxidant defenses*

Ribose may support the body’s innate antioxidant mechanisms while promoting an antioxidant effect of its own. Intense exercise and other strenuous activity can induce the production of free radicals. Preliminary studies suggest that ribose can attenuate some of the effects of oxidation seen after performance of intensive exercise.

One small human study indicated that ribose administered at a dose of seven grams before and after a bout of cycling exercise may reduce free radical production.6 Seven volunteers ingested either ribose or placebo both before and after intense exercise. Markers of lipid peroxidation, including malondialdehyde, significantly decreased in the ribose-supplemented group, while increasing in the control group. The results of this study indicate a possible effect of ribose in supporting antioxidant activity.

Supports healthy energy levels in heart and muscle tissue*

After bouts of intense exercise, ATP levels have been shown to decrease by an average of 15 to 20%.7 The amount of ATP stored in the muscle is limited and so the body must have the potential to rebuild ATP stores. ATP is the fuel necessary for the integrity and function of a cell. In addition, several studies have found correlations between ATP content and heart function.1 Research that was also alluded to above suggests that ribose stimulates ATP synthesis and supports heart and muscle function by enhancing ATP levels in cardiac and muscle tissue. D-ribose is an essential building block for the synthesis of ATP through the pentose phosphate pathway. 

The results of ribose supplementation enhancing ATP levels in muscle are evidenced by studies suggesting beneficial effects on anaerobic performance. In a randomized, placebo-controlled crossover study assessing the effects of acute ribose supplementation, participants receiving the ribose supplement had increases in mean power (a measure of average overall muscular strength output during the sprint) and peak power (a measure of the highest muscular strength output during the sprint) when undergoing a series of cycle sprints.8 While this effect was not noted in all of the six short cycling sprints that the participants underwent, the study does illustrate the potential benefits of ribose on ATP production and, secondarily, on enhancing exercise performance.

A second placebo-controlled trial investigated the effects of four weeks of ribose-supplementation (10 grams /day) on male bodybuilders. Of the 20 participants who were recruited, twelve completed the study. Each subject participated in a heavy-resistance training program designed to increase skeletal muscle mass. The effects of ribose on body composition (body weight, body fat, lean body mass, fat mass, and bone mineral content) were also assessed. The results suggested that ribose increased total work capacity and bench press strength compared to placebo, without altering body composition.9

Supports energy recovery after exercise*

Animal studies have suggested that the administration of ribose after exercise increases the rate of adenine salvage by five to seven-fold in muscle tissue7, supporting energy recovery after exercise. When ATP is utilized by muscle tissue, the degradation products include adenine nucleotides (Adenine is one of two purine bases that is a component of DNA). Adenine is recycled to synthesize DNA, and the salvage of adenine within the muscle tissue is crucial to energy recovery. Studies have shown that the presence of adequate ribose concentrations is the rate-limiting step in the purine salvage pathway. Therefore, increased adenine salvage could potentially help in the recovery and regeneration of ATP after intense bouts of activity.

A study investigated the effect of oral intake of ribose on the synthesis of AMP, a precursor to ATP.10 Participants performed intense cycle training for seven days. They then received either ribose (at a concentration of 200 mg/kg body weight, which is equivalent to 14 grams per day for an average 70 kilogram male) or placebo three times a day for the following three days. Exercise tests were performed again on day 4. Muscle biopsy samples were taken before the first training session, immediately after, and again five hours, 24 hours, and 72 hours after the last training session. No differences were seen in exercise performance between the groups. The intense exercise caused the ATP levels in muscle to decrease in both groups. However, at 72 hours post-exercise, the ribose group exhibited a much higher ATP level than the placebo group. The muscle levels of critical building blocks for ATP, including total adenine nucleotides (TAN) and inosine 5’-monophosphate (IMP), were also significantly higher in the ribose group compared to the placebo group at 24 hours after exercise. Ribose-supplementation was shown to enhance the resynthesis of ATP after intense exercise.

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Safety

Caution: Insulin-dependent diabetics and pregnant women should consult their physician before use.

Suggested Adult Use: Take 1 or 2 scoops mixed in water, juice or other beverage two times per day. May be taken with or without food.

Scientific References

1) Pliml, W., von Arnim, T., Stablein, A., Hofmann, H., Zimmer, H., Erdmann, E. Effects of ribose on exercise-induced ischaemia in stable coronary artery disease. The Lancet. 1992;340:507-510.

2) Omran, H., Illien, S., MacCarter, D., St. Cyr, J.A., Luderitz, B. D-Ribose improves diastolic function and quality of life in congestive heart failure patients: a prospective feasibility study. The European Journal of Heart Failure. 2003;5:615-619.

3) Illien, S., Omran, H., MacCarter, D., St. Cyr, J.A. Ribose improves myocardial function in congestive heart failure. FASEB Journal 2001;15(5): A1142

 

4) Muller C., Zimmer H., Gross M., Gresser U., Brotsack I., Wehling M., Pliml W. Effect of ribose on cardiac adenine nucleotides in a donor model for heart transplantation. Eur J Med Res. 1998 Dec 16;3(12):554-8.

5) Zimmer H.G. Normalization of depressed heart function in rats by ribose. Science. 1983 Apr 1;220(4592):81-2.

6) Seifert, J.G., Subudhi, A., Fu, M., Riska, J.J. The effects of ribose ingestion on indices of free radical production during hypoxic exercise. Free Rad Biol Med 2002; 33(Suppl 1) S269.

7) Zarzeczny, R., Brault, J.J., Abraham, K.A., Hancock, C.R., Terjung, R. Influence of ribose on adenine salvage after intense muscle contractions. J Applied Physiology. 2001;91:1775-1781. 

8) Berardi J.M., Ziegenfuss T.N. Effects of ribose supplementation on repeated sprint performance in men. J Strength Cond Res. 2003 Feb;17(1):47-52.

9) Van Gammeren, D.V., Falk, D., Antonio, J. The effects of four weeks of ribose supplementation on body composition and exercise performance in healthy, young, male recreational bodybuilders: a double-blind, placebo-controlled trial. Current Ther Research. 2002;63(8):486-495.

10) Hellsten, Y., Skadhauge, L., Bangsbo, J. Effect of ribose supplementation on resynthesis of adenine nucleotides after intense intermittent training in humans. American Journal of Physiology – Regulatory, Integrative and Comparative Physiology. 2004;286:R182-R188.



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Safe Solutions for Chronic Pain
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Date: March 30, 2007 12:09 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Safe Solutions for Chronic Pain

Safe Solutions for Chronic Pain

 

One of the biggest challenged in healthcare today is the problem of pain. There are simply too many people living each and every day with ongoing, unremitting chronic pain. And there are far too many healthcare providers who – for a variety of reasons – are failing to adequately address this serious problem.

Recently, 368 doctors who routinely care for patients with chronic pain agreed to take part in a unique study. The doctors were surveyed about the pain medicines hey prescribe, what kind of treatment goals they hope to achieve, and how they felt about their ability to help their patients. They were also presented with four chronic pain vignettes or mock case studies and asked to select the best treatment for each scenario from multiple choice answers.

Sadly, many doctors chose the worst treatment options in the case studies. The medications they reported using in their practices did not reflect current pain treatment standards. They tended to set low treatment goals 0 instead of aiming for a least a 75% reduction of pain for their patients, they settled for 10% to 20% reductions. And many of the doctors admitted they lacked confidence in their ability to relieve their patients’ pain and suffering.

Adding to the challenge are the almost daily news announcements about dangerous side effects in certain pain medications. Synthetic prescription COX-2 inhibitors, once hailed as the safest of drugs, have been linked to heart attacks, strokes, blood clots, and intestinal bleeding. The over-the counter (OTC) drugs aspirin and ibuprofen kill over 16,000 people each year. And acetaminophen, the most widely used pain reducer in the United States is the leading cause of drug-induced liver failure.

As a doctor specializing in chronic pain disorders, I know that optimal pain management can be a real challenge. However, I also know:

-You do not have to live in chronic pain.

-Your chronic pain, no matter what the cause, can be reduced, and usually

eliminated.

-Chronic pain can be relived both effectively and safely with powerful all-natural

compounds.

Q. What is chronic pain?

A. Sudden, or acute, pain occurs when pain signals immediately fire in your nervous system alerting you to an injury, like a broken ankle, or an illness, such as appendicitis. Once the injury heals or the illness is cured, the transmission of pain signals stop.

Ongoing – or chronic pain – is much different. Chronic pain persists. Pain signals keep firing in the nervous system for weeks, months, even years. There may have been an initial injury, such as sprained back muscles, or an initial illness, such as a serious infection. There might be an ongoing cause of pain, such as arthritis, cancer, or fibromyalgia. Chronic pain also occurs without any past injury or evidence of body damage.

The most common kinds of chronic pain are headache, low back pain, cancer pain, arthritis pain, and neurogenic pain (pain resulting from damage to nerves or to the nervous system itself). While chronic pain differs in its origin and where it occurs, it is generally your body’s way of saying that something urgently needs attention, and will not o away unless its underlying causes are addressed.

These causes can usually be determined if you remember the acronym “SHIN”. This stands for Sleep, Hormonal deficiencies, Infections/Inflammation/Impingement, and Nutritional deficiencies. When these are treated, pain often resolves.

Q. Why is it so hard to effectively reduce chronic pain?

A. Unfortunately, many physicians’ entire education in pain management consists of “giving nonsteroidal anti-inflammatory drugs or NSAIDs (pronounced en-sayds), COX-2 inhibitors, or acetaminophen and considering narcotics if the patient has cancer.

Some NSAIDs, like aspirin and ibuprofen, are available over-the-counter, while others, like the synthetic COX-2 inhibitors are only available with a doctor’s prescription. These mediations are usually inadequate and often toxic when used for chronic pain. And they do not address the problem(s) that the pain is trying to alert you to.

Q. What exactly are COX-2 inhibitors?

A. COX-2 inhibitors do pretty much what their name implies – they inhibit a natural enzyme in our body called the clclooxygenase-2, or COX-2, enzyme. There are two COX enzymes – COX-1 and COX-2 and both complete several actions in our bodies. One very important action that both COX-1 and COX-2 enzymes share is the speeding up of our body’s production of prostaglandins. These hormone-like substances are made by the cells of the body and have several important functions.

Some of the most powerful prostaglandins cause inflammation, pain, and fever when we are sick or injured. Prostaglandins also protect the lining of the stomach from the damaging effects of acid. Other prostaglandins make sure our platelets (important blood cells) make blood clots when needed. Still others help our kidneys get rid of unwanted salt and water. And researchers have just recently recognized the importance of still another prostaglandin that protects our heart and blood vessels.

The NSAIDs reduce pain by reducing prostaglandin production by blocking or inhibiting the COX enzymes. In theory – less prostaglandins, less pain and welling seems reasonable. But if you really stop and think about it, it’s pretty easy to understand why this method of pain relief might result in significant consequences.

Pain and inflammation are often needed for healing. And just as needed is the protection of our stomach lining, blood clotting ability, assisting kidney function, and keeping our blood vessels healthy. And scientists are beginning to understand if you interfere with one natural response, you may be disrupting the body’s ability to prevent extremes and imbalances.

That’s why using aspirin and ibuprofen can result in stomach ulcers, kidney problems, and internal bleeding. And that’s why using synthetic COX-2 inhibitors can result in high blood pressure, blood clots, heart attacks, and strokes.

Q. Why are we just now learning about the dangers of COX-2 inhibitors and other NSAIDs?

A. That’s a good question!

Many people over the age of 65 have chronic pain conditions and are frequent users of OTC and prescription NSAIDs. This age group also experiences heart disease and Alzheimer’s disease in greater numbers. So, if a 70 year old woman who’s been using Celebrex for the past two years for arthritis in her knees suddenly has a heart attack one morning, it would not be entirely unexpected.

For the past five or six years, researchers have been studying the possibility that NSAIDs may prevent certain cancers, Alzheimer’s disease, and other health problems. The ongoing, close scrutiny of large group of people taking these medications by scientists who were conducting these studies has resulted in the discovery of these dangers.

Q. What kind of natural compounds relieve chronic pain?

A. There are many – glucosamine, Omega-3 fatty acids, the B vitamins – the list goes on and on. Instead of disrupting normal bodily responses, these natural compounds work in harmony with our body to eliminate chronic pain. Three very powerful and very effective all natural plant compound pain and inflammation relievers are Sweet Cherry, Boswellia serrata, and White Willow Bark.

For many years there have been anecdotal or personal reports that claimed eating Sweet Cherries, specifically Prunus avium, wipes out back pain, arthritis, and gout. While anecdotal reports generally don’t account for much in the world of science, he sheer numbers of testimonials proclaiming the Sweet Cherry’s amazing ability to reduce pain made researchers sit up and take notice.

When Sweet Cherries were examined in the lab, it was easy for scientists to understand how this natural fruit is able to relieve pain. It seems Sweet Cherry’s bright red color is the key. Like many deeply colored fruits, Sweet Cherries are full of flavonoids called anthocyanins and proanthocyanidins.

These powerful plant compounds scavenge and destroy altered oxygen compounds called free radicals. Many degenerative, chronic diseases have been associated with the tissue damage caused by free radicals, including arthritis, heart disease, peripheral artery disease, and cancer. Cherry fruit extract is a natural anti-inflammatory compound, making it an excellent treatment for arthritis, fibromyalgia, and other chronic pain and inflammation diseases.

A pain relieving plant compound that comes from the bark of a tree, Boswellia serrata has been used by Indian healers for hundreds of years to reduce painful inflammation. When 20th century researchers looked at extracts of Boswellia Gum Resin in the laboratory they discovered the presence of powerful plant compounds, called boswellic acids.

Researchers found Boswellic Acids reduce inflammation in several ways. They open constricted blood vessels, improving blood flow to joints. They balance levels of leukotrienes – specific chemicals in the body that cause inflammation. And Boswellic Acids block two inflammatory chemicals that increase in asthma and inflammation of the colon. In addition to being helpful in treating these 2 illnesses, Boswellia has also been clinically studied and found to be quite effective in osteoarthritis and rheumatoid arthritis without any evidence of ulcers or stomach irritation.

Another bark extract, White Willow Bark is one of the oldest and most effective pain relievers. For over 2,000 years extracts from the bark of the White Willow tree have been used to ease aches and pains and reduce fevers. It is the original source of aspirin, but when used as the entire plant medicine, White Willow Bark is much safer than aspirin and quite effective.

White Willow Bark’s active ingredient is salicin and the combination of other compounds in the bark significantly enhances its pain killing power. In two large clinical trials of patients with chronic low back pain. White Willow Bark was found to be not only safer and much more effective than standard prescription therapies, it was also 40 percent more cost effective.

Salicylic acid from White Willow Bark lowers the body’s levels of prostaglandins, easing both acute and chronic pain. White Willow Bark reduces the pain and swelling of arthritis, headache, back and neck pain, muscle aches, and menstrual cramps. But, unlike aspirin, it doesn’t cause stomach bleeding or other known adverse effects.

Q. Do Sweet Cherry, Boswellic Acids, and White Willow Bark work on many kinds of chronic pain?

A. They do indeed. Because they reduce both pain and inflammation by a broad combination of actions, these natural extracts have been proven to be excellent against arthritis, back pain, and pain from inflammatory intestinal diseases (Crohn’s disease and ulcerative colitis), and would be expected to be helpful in most kinds of pain.

Sweet Cherry, Boswellic Acids, and White Willow Bark relieve inflammation without causing stomach irritation, stomach ulcers, high blood pressure, blood clots, heart attacks, or strokes. That’s because these natural pain killers don’t disrupt the balance of enzymes or interfere with the body’s ability to prevent extremes and imbalances.

However, as with any pain therapy, Sweet Cherry, Boswellic Acids, and White Willow Bark work best when they are used as part of a comprehensive treatment plan to relieve the most common underlying causes of chronic pain or SHIN.

In addition, although these excellent natural remedies can often offer quick pain relief, natural remedies for severe chronic pains work best when they are given at maximum allowed doses and given 6 weeks to show their full effectiveness in combination with treating the pain’s underlying causes. The best chronic pain relief results when doctors and patients work together to meet the goals of treatment.

Some important last notes: Many causes of chronic pain are serious and life threatening. Everyone who is living with chronic pain must consult their doctor or other healthcare practitioner to determine the reason for their ongoing discomfort. In other words – make sure you know why you are having chronic pain and what’s causing the pain you want to relieve.

There are some types of chronic pain that only respond to opioids, or narcotic pain relievers. Morphine sulfate is an excellent pain medication and is used to relieve surgical pain, the pain of heart attacks, and pain from serious injuries. Morphine is also the very best drug for chronic cancer pain and non-malignant chronic pain. While many people fear opioids, these powerful pain killers can dramatically improve quality of life. If you are suffering with chronic cancer pain and you are hesitant to use morphine or another opioid, I urge you to discuss your concerns with your doctor other healthcare provider. No one with cancer should live with untreated or under-treated pain.

 

Conclusion

Even chronic pain can often be eliminated when SHIN is in combination with powerfully effective natural pain relievers. But, because some people may need to take pain relievers the rest of their lives, the medications they use must be safe as well as effective. The very safest come from natural plant compounds that have been studied for their ability to relieve chronic pain. You can become pain free and Sweet Cherries, Boswellic Acids, and White Willow Bark can help.



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Regulating Blood Pressure Naturally
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Date: March 28, 2007 10:29 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Regulating Blood Pressure Naturally

Regulating Blood Pressure Naturally

 

High blood pressure (also known as hypertension) affects about 65 million Americans, or about 1 in 3 adults. There are many potential causes of hypertension, but not necessarily any symptoms. In fact, 30% of the people who have high blood pressure don’t even realize it.

In other words, just because you don’t have symptoms doesn’t mean you don’t have high blood pressure. That’s why it’s called “The Silent Killer.” And, make no mistake about it: high blood pressure is dangerous. It is the number one modifiable cause of stroke. Just lowering blood pressure reduces the chance of stroke by 35 to 40 percent. Other conditions, including heart attack and heart failure can be reduced from 25 to 50 percent, respectively.

In this issue of Ask the Doctor, we’re going to talk about high blood pressure and an exciting natural treatment for lowering blood pressure safely and effectively.

Of course, changing blood pressure numbers depends, in a large part, on the choices we make every day – how much we exercise, the foods we eat, and our lifestyle overall. But, for those times we need extra help, there is a new, scientifically-studied supplement to help us along our path to better health and lower blood pressure.

 

Blood pressure guidelines from the National Heart, Lung, and Blood Institute.

Category

Systolic (mm/Hg)

Diastolic (mm/Hg)

Result

Normal

Less than 120

And Less than 80

Excellent!

Prehypertension

120-139

Or 80-89

Make changes in eating and drinking habits, get more exercise and lose any extra pounds.

Hypertension

140 or higher

Or 90 or higher

You have high blood pressure. Talk to your healthcare professional on how to control it.

 

Q. What exactly is blood pressure?

A. Blood pressure is divided into two parts, systolic and diastolic. Systolic is the pressure of the heart beating. Diastolic is the pressure of the heart and vessels filling. When blood pressure numbers are written out, like “120/80,” 120 is the systolic pressure and 80 is the diastolic pressure. The unit of measurement for blood pressure is millimeters of mercury, written as “mm/Hg.”

 

Q. What is considered high blood pressure?

A. A person’s blood pressure can naturally vary throughout the day – even between heartbeats.

However, if the numbers are consistently high (over 120 systolic and 80 diastolic), after multiple visits to your healthcare practitioner, you may have either pre-hypertension or high blood pressure.

Young arteries and arteries that are kept young through healthy diet and exercise are typically more elastic and unclogged. Blood flows through them easily and without much effort. However, as we age, our arteries become more prone to plaque buildup (due to diets high in saturated fat and sedentary lifestyles) and don’t “flex” as well under pressure. The result is faster blood flow, all the time. Over the long term, it damages heart tissue, arteries, kidney and other major organs.

To get a better idea of high blood pressure, compare your arteries to a garden hose. When unblocked, a garden hose allows water to flow through it quickly and easily – without any real rush or stress. However, if you block the end of the hose with your thumb, closing it off even a little, water rushes out much more quickly.

For many years, high diastolic pressure was considered even more of a threat than high systolic pressure. That thinking has changed somewhat but high diastolic numbers could still mean organ damage in your body – especially for individuals under 50.

 

Q. What courses high blood pressure?

A. The reasons for hypertension aren’t always clear. However, there are lifestyle factors that contribute to high blood pressure that you can change:

 

Body type: Weight isn’t always a reliable indicator of whether or not you’ll have high blood pressure – but the type of weight is. Lean body mass – muscle – doesn’t increase blood pressure levels the way that fat can. However, fat body mass, especially fat around your middle, can contribute to high blood pressure.

 

Sedentary lifestyle: Too often, many of us sit down all day at work, and then sit down all night at home. Over time, this inactivity usually leads to weight gain, making the heart work harder to pump blood through the body. In a way, it almost seems contradictory, but inactivity usually leads to higher heart rates.

 

Sodium intake: Sometimes it’s hard to believe how much salt there is in processed foods. However, salt intake in itself is not necessarily bad. For people with a history of congestive heart failure, ischemia, and high blood pressure, sodium is definitely out. For those individuals, it leads to more water retention, which increases blood pressure. (Salt’s effect on water retention is one reason that so many sports drinks have fairly high sodium content – the sodium in the drink prevents your body from sweating out too much water.) But, for healthy individuals, moderate salt intake, especially a mixed mineral salt like sea salt or Celtic salt (good salt should never be white) is fine.

 

Low potassium intake: Unlike sodium, potassium is a mineral which most Americans get too little of. Potassium helps regulate the amount of sodium in our cells, expelling excess amounts through the kidneys. Low levels of this mineral can allow too much sodium to build up in the body.

 

Heavy alcohol intake: Having three or more alcoholic drinks a day (two or more for women) nearly doubles an individual’s chance of developing high blood pressure. Over time, heavy drinking puts a lot of stress on the organs, including the heart, liver, pancreas and brain.

 

Unhealthy eating: Eating a lot of processed or fatty foods contributes to high blood pressure. Adapting a diet that is rich in fruits and vegetables, whole grain products, fish, nuts and magnesium and potassium (like the Dietary Approaches to Stop Hypertension, known as the “DASH” diet) can bring it back down.

 

Smoking: If you smoke, stop. Smoking damages the heart and arteries – period. Nicotine constricts blood vessels, increases heart rate, and raises blood pressure. This in turn, increases hormone production and adrenaline levels, further stressing the body.

 

As if that weren’t bad enough, the carbon monoxide in cigarette smoke replaces the oxygen in the blood, making the heart work even harder to make up the difference. Since the effect of a single cigarette can last for an hour, smoking throughout the day leads to continuously revved-up blood pressure.

 

Some of these factors might sound like a lot to overcome. The important thing to remember is that all of these behaviors are changeable. If you have high blood pressure, modifying any of these can significantly lower blood pressure as part of an overall plan.

 

Q. What are the blood pressure numbers I should see?

A. Experts consider healthy blood pressure numbers to be 115/75 mm/Hg. The reason? They found that the risk of cardiovascular disease doubles at each increment of 20/10 mmHg over 115/75 mm/Hg. Even small jumps in blood pressure numbers increase the risk of stroke and heart attack.

 

Q. Okay, so other than diet, exercise and lifestyle changes are there other natural ways or supplements I can use to lower my blood pressure?

A. Yes, in fact, you hear about some of them in the news all the time – fish oil, CoQ10, and garlic. As effective as these symptoms are, they typically lower systolic pressure much more than diastolic pressure.

However, there is a blend of scientifically and clinically studied natural ingredients that lower high blood pressure separately, and work even better when they’re combined. This combination blend contains: dandelion leaf extract, lycopene, stevia extract, olive leaf extract and hawthorn extract.

Every one of these ingredients has been studied and recommended for years. But now, a scientific study on a supplement that combines them in one synergistic formula shows encouraging results for lowering systolic and diastolic blood pressure.

Let’s take a look at each:

Stevia leaf extract

Supports healthy blood pressure levels according to clinical studies.

Hawthorn extract

Supports the heart and balance sodium and fluid levels.

Olive leaf extract

Scientifically shown to support healthy blood pressure.

Dandelion leaf

Helps reduce fluid retention

Lycopene

Clinically shown to support arteries, circulation and heart health.

 

Stevia:

Stevia (Stevia rebaudiana) originated in South America, and is often used as a sweetener. Glycosides in stevia, particularly stevoside, give the plan its sweet flavor 0 anywhere from 100 to 200 times sweeter than sugar.

The leaf of stevia is considered the medicinal part of the plant. Research shows that extracts of the leaf relax arteries and help prevent the buildup of calcium on artery walls – keeping them healthy and reducing blood pressure.

In a long-term, randomized, placebo-controlled clinical study, stevia reduced systolic and diastolic blood pressure. On average, participants’ blood pressure reduced from baseline 150 mm/Hg to 140 mm/Hg systolic and 95 mm/Hg to 89 mm/Hg diastolic.

And, in another double-blind, placebo-controlled clinical study, stevia lowered blood pressure quite significantly – by an average of 14 millimeters of mercury in both systolic and diastolic readings. Those are impressive numbers!

Despite its role as a sweetener, stevia may have a side benefit to for those with hypertension – blood sugar regulation. Scientific studies show that extracts of stevia regulated blood sugar and reduced blood pressure.

A clinical study showed that stevia extract actually improved glucose tolerance by decreasing plasma glucose levels during the test and after overnight fasting in all participants. Regulating blood sugar is very important for those with high blood pressure. When blood sugar levels are high, blood vessels are inflamed. Many people with diabetes have high blood pressure as well. In a paired, cross-over clinical study, stevioside (one of the compounds in stevia) reduced glucose levels in individuals with type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. It shows great potential in treating type 2 diabetes. Further scientific studies show that stevia works to control blood sugar levels by stimulating insulin secretion by the pancreatic beta cells. Its shows great potential in treating type 2 diabetes as well as hypertension.

 

Hawthorn extract:

Hawthorn (Crataegus spp. Oxycantha) has been used since ancient ties as a medicinal herb – even being mentioned by the Greek herbalist Dioscorides, in the first century AD. Traditionally, it has generally been used for support of the heart. Modern research points to bioflavonoid-like complexes in hawthorn leaf and flower that seem to be most responsible for its benefits on cardiac health, like blood vessel elasticity.

The bioflavonoids found in hawthorn include oligomeric procyanidins, vitexin, quercetin, and hyperoside. They have numerous benefits on the cardiovascular system. Hawthorn can improve coronary artery blood flow and the contractions of the heart muscle. Scientific studies show that the procyanidins in hawthorn are responsible for its ability to make the aorta and other blood vessels more flexible and relaxed, so that blood pumps more slowly and with less effort – sparing the cardiovascular system such a hard workout.

The procyanidins in hawthorn also have antioxidant properties – protecting against free radical cellular damage.

And, hawthorn may also inhibit angiotensin-converting enzyme. Angiotensin-converting enzyme is responsible for retaining sodium and water, and may have roots in our evolutionary development. It influences blood vessel contraction and dilation, sodium and water balance and heart cell development – just about everything that has to do with blood pressure. This may have developed as a way of dealing with periods of drought and stress. By narrowing the blood vessels, the body could guarantee an adequate supply of blood and focus on repairing tissue.

Unfortunately, that can lead to real problems these days. Since many of us live in an industrialized society, and frequently have pretty sedentary lifestyles, conserving sodium just makes the conditions for high blood pressure that much worse.

Like the other ingredients in this combination, hawthorn showed benefits on other body systems, too. In clinical and scientific studies, it not only lowered blood pressure, but also showed anti-anxiety properties and regulated blood sugar.

 

Olive leaf extract:

Olive leaf (Olea europaea) comes up again and again in scientific and clinical studies as having beneficial effects on hypertension. One of olive leaf’s most beneficial compounds is oleuropein – the same compound that makes olive oil so helpful in reducing blood pressure. Here again, we have to look at the traditional Mediterranean diet, which features voluminous use of olives and olive oil. Not surprisingly, blood pressure is generally much lower in Greek and Italian populations.

But it’s not just the diet – scientific studies showed that oleuropein lowered blood pressure by relaxing the blood vessels and prevented buildup of plaque in arteries. Plus, whether in olive leaf extract or in olive oil, oleuropein works as an antioxidant, too.

 

Dandelion leaf extract:

Dandelion (Taraxacum offinale) leaves provide a healthy supply of vitamins, much like spinach. In fact, although it has become the bane of North American gardeners and lawn owners, dandelion greens are a component of many gourmet salads.

Medicinally, dandelion has been used for centuries, dating back to ancient Greece. Leaves intended for medicinal use are harvested before flowering, to ensure the most nutrients.

They are a very rich source of vitamin A, and contain vitamin D, vitamin C, carious B vitamins, iron, silicon, magnesium, zinc and manganese, too. Dandelion leaves produce a diuretic effect in the body, similar to a prescription drug. Since one of dandelion leaf’s traditional uses was the treatment of water retention, it’s really not too surprising. Dandelion leaf is also rich in potassium – one of the vital minerals many Americans lack in their diet. So, even though it may act as a diuretic, it replaces more potassium than the body expels.

The diuretic effect of dandelion can relieve hypertension by drawing excess water and sodium from the body and releasing it through the kidneys as urine. Getting rid of extra water and sodium allows the blood vessels to relax – lowering blood pressure.

 

Lycopene:

If a nutrient can be called exciting, lycopene is it. Lycopene is found mostly in tomatoes and processed tomato products, like pasta and pizza sauce. Related to beta-carotene lycopene shows great antioxidant abilities among its many talents. In fact, it shows even greater free-radical scavenging properties than beta-carotene, its more famous cousin. Healthy intakes of lycopene can guard against a variety of chronic conditions, including lowering LDL (bad) cholesterol, lowering homocysteine levels and reducing blood platelet stickiness that can lead to clogged arteries. It’s even being studied for its protective effect against prostate cancer.

And, for proof, you don’t have to look too far to see the amazing effect lycopene intake can have on health. The Mediterranean diet provides an excellent example. Its high intakes of vegetables, (tomatoes, of course, playing a central role) fish, and whole grains improve cholesterol levels and lower blood pressure. The research on lycopene as a stand-alone nutrient has been compelling. A randomized clinical trial found that not having enough lycopene was associated with early thickening of the arteries.

So, it makes sense that other clinical trials, showed that higher intakes of lycopene frequently meant less thickening of arteries, and a reduced risk of heart attack. In one study, the risk of heart attack was 60% lower in individuals with the highest levels of lycopene. In a multicenter study, similar results were found – men with the highest levels of lycopene had a 48% lower risk of heart attack.

 

Q. What can I expect taking this herbal combination?

A. You should notice both systolic and diastolic numbers lowering in about two weeks. The scientific study showed that for pre-hypertensive and stage I, (early hypertensive individuals) this combination for ingredients lowers both systolic and diastolic blood pressure.

When you’re taking herbs to support your blood pressure, it’s important to keep it monitored so you have an accurate reading (and record) of your numbers. If you need to, you can pick up a home blood pressure monitoring device. These can retail for anywhere from $30 all the way up to $200, but buying one in the $30 to $50 range is a good idea and money well spent. Consider taking the machine to your local doctor’s office or fire department to have it tested for accuracy against a professional blood pressure monitor. See the chart below for tips on getting an accurate reading from a home monitor.

 

Tips for Accurate Blood Pressure Monitoring:

-Relax for about 5 to 10 minutes before measurement.

-If you have just come inside from cold outdoors allow yourself to warm up.

-Remove tight-fitting clothing and jewelry.

-Unless your physician recommends otherwise, use left arm to measure pressure.

-Sit, don’t stand.

-Remain still and do not talk while using the monitor.

 

Q. Are there any side effects?

A. There were no side effects noted in the study. However, because of the mild diuretic effect of dandelion leaf extract, you may notice an increase in trips to the bathroom. It’s always important to make sure you don’t get dehydrated, so you may want to drink more water during the day.

 

Conclusion:

High blood pressure doesn’t happen overnight. As we get older, the likelihood of developing hypertension increases. And, stressful, fast-forward lifestyles, bad diets and no exercise conspire to raise our blood pressure.

 

In my own practice I have helped patients move toward a healthier lifestyle, including diet, exercise, and blood-pressure reducing supplements. They live better, more vibrant lives as a result, and their blood pressure normalizes. It really can happen – you can bring your blood pressure back to normal, and this combination of scientifically and clinically validated ingredients can help.



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Peppermint Oil for IBS
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Date: March 24, 2007 11:01 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Peppermint Oil for IBS

Irritable bowel syndrome (IBS) is a painful and frequently frustrating disorder of the intestines that’s often difficult to treat. Fortunately, there are scientifically studied natural products that effectively reduce the distressing symptoms of IBS.

Q. What is IBS?

A. IBS causes crampy pain, gassiness, bloating, and alterations in bowel habits. IBS is termed a functional disorder, because when the colon is examined, there is no visible sign of disease. While IBS causes significant pain and distress, no actual damage is occurring in the intestines.

There is a wide variability in IBS. Symptoms may be mild and fairly well tolerated. Or, the pain, discomfort, and bowel dysfunction may be disabling, limiting social interactions, employment, or travel.

While some individuals with IBS have diarrhea (frequent, loose stools with an urgent need to move the bowels), others have constipation (hard, infrequent stools that are difficult to pass). And, still others may experience both. Individuals with IBS also may have painful abdominal cramps and feel an urgent need to move the bowels, but are unable to do so.

Q. What causes IBS?

A. The small intestine receives digestive material from the stomach and delivers it to the large intestine (colon). About two quarts (2,000 ml) of digestive material enter the colon from the small intestine every day. The colon absorbs water and salts from the material, which is progressively moved through the colon. This progressive movement continues until most of the fluid and salts are absorbed into the body and stool is formed. The stool passes to the left side of the colon, where it is stored until a bowel movement occurs.

Because researchers haven’t been able to find actual damage in the colon, it once was suggested that individuals with IBS have emotional problems or are overly susceptible to stress. While stress may cause symptoms of IBS to intensify, it doesn’t cause the condition.

Recent study has determined the colon muscle of an individual with IBS spasms after only mild stimulation. It’s thought the symptoms of IBS are produced by hyperactivity of the intestines. In other words, the intestines of individuals with IBS are more reactive to stressors and diet than usual. Almost everyone has experienced abdominal queasiness in response to everyday stress or certain foods. This may result in a brief bout of diarrhea or an upset stomach. However, this response is exaggerated in individuals with IBS.

Q. How prevalent is IBS?

A. IBS is very common. In fact, it’s one of the most frequent problems seen by family physicians. It’s the most common disorder diagnosed by gastroenterologists (physicians specializing in the treatment of digestive disorders). The overall prevalence rates range from 10% to 20% of the general population in most industrialized countries. As a result, the pain and disabling symptoms associated with IBS result in significant socioeconomic costs, as wall as reduction in quality of life for many individuals.

Q. What are the symptoms of IBS?

A. Normal bowel function varies from person to person. Some people move their bowels daily, while others may only have two to three stools a week. A normal bowel movement is soft, formed, and is easily passed without cramping or pain.

IBS, however, causes abdominal cramps and pain, which are often severe and disabling. Bowel movements may be irregular and alternate between diarrhea and constipation. The diarrhea may be quite loose and watery. Mucous may be passed. There is often much straining, urgency, and feeling of incomplete evacuation (emptying). Abdominal bloating and passing of gas is common. Nausea, lack of appetite, heartburn, and belching may also be present. Sleep may be disrupted resulting in fatigue and lack of energy. Understandably, persons with IBS often feel anxious and depressed.

Diagnosis of IBS is usually based on the continuous presence or recurrence of these symptoms for at least three months. Other intestinal conditions must be ruled out. These include Chron’s disease, ulcerative colitis, inflammatory bowel disease, colon cancer, inflammatory conditions of the stomach or pancreas, ulcers, infectious disease, or gastroesphageal reflux disease.

Q. Are there clinically demonstrated natural alternatives to the over-the-counter drugs prescribed by my doctor?

A. Yes, both enteric-coated peppermint oil and clown’s mustard (in combination with other herbs) have significant scientific research behind them. Both have been demonstrated to benefit individuals with IBS.

Q. What is clown’s mustard and what does it do?

A. The scientific name for clown’s mustard is Iberis amara. Other names for this herb are wild candytuft and bitter candytuft. Clown’s mustard is a white-flowering plant from Spain, where it grows in dry soil on hillsides and in cornfields. It is also grown in Britain, France, and the United States. Iberis amara is a member of the Brassicaceae family. Iberis refers to its place of origin, the Iberian Peninsula. Amara means bitter. The key components of clown’s mustard are glycosides and flavonoids that have specific actions on gastrointestinal tract tone.

Q. Is there scientific evidence that clown’s mustard benefits people with IBS?

A. There has been very impressive research on clown’s mustard (in combination with other herbs). And, it has been used with great success in Germany for many years to treat IBS and other gastrointestinal diseases.

In a study of an herbal combination containing clown’s mustard, 20 patients were given the herbal combination for three to 32 days. They all had been diagnosed with chronic functional disorders for at least one to 20 years. The symptoms the patients experienced included pressure and pain in the abdomen, belching, heartburn, vomiting, nausea, fullness, lack of appetite, constipation, and diarrhea. The patients have been treated for their problems with a variety of antacids, anti-spasmodic agents, and motility-inducing substances. For the purposes of the study, the patients stopped taking these medications and received treatment only with the herbal combination.

Abdominal pressure and pain in the abdomen was the most common of all the experienced symptoms, with 11 of the patients rating it as severe. After six days of treatment, only sic of the patients continued to rate their abdominal pain and pressure as severe. After two weeks, this symptom had completely resolved for 16 of the patients. Diarrhea had been rated as severe in five of the patients. By day 14, only one patient continued to have moderate diarrhea.

Medications prescribed and taken for cardiovascular diseases, arthritis, and autoimmune diseases often cause gastrointestinal problems. Because these conditions are chronic, these medications must be taken for a long time, often for life. With long-term use, these medications can cause erosion of the stomach lining and actual ulcers. Many of these medication-caused symptoms are similar to IBS symptoms: pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Most, if not all, of the individuals who have gastrointestinal problems caused from medications experience two or more of these IBS symptoms.

Forty patients who were taking medications for various types of cardiovascular disease and arthritis, and who are experiencing gastrointestinal problems related to their medications, were enrolled in a study. These symptoms included pressure and pain in the upper abdomen, nausea, abdominal fullness, and lack of appetite. Twenty patients received clown’s mustard combined with other herbs that support gastrointestinal motility. Three days after the trial started, a significant improvement of all s symptoms was noted in those taking this combination. By day 14, abdominal pressure and pain, nausea, and heartburn were completely eliminated in the herbal combination group. Several other clinical trials that were conducted in Germany report similar results.

Q. How does this herb compare to prescription drugs?

A. A study compared clown’s mustard (combined with other herbs) to Reglan (metoclopramide), which is frequently prescribed to reduce the symptoms of IBS. While metoclopramide is a very effective medication, it also has numerous side effects. Metoclopramide can cause fatigue, anxiety, agitation, jitteriness, insomnia, yellowing of the skin or eyes, changes in vision, hallucinations, and seizures. Because of these serious side effects, metoclopramide must not be taken longer than 12 weeks.

In comparison study, 77 subjects were randomized to receive treatment of either clown’s mustard in a combination with other herbs, or metoclopramide. All subjects had pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. The subjects took 20 drops of their assigned treatment after meals three times daily. The duration of treatment was one to two weeks.

In both groups, a parallel improvement of all symptoms was observed. At no point in the study was a statistically significant difference in symptoms found. Both treatments significantly reduced pain and pressure in the abdomen, cramping, abdominal fullness, nausea, heartburn, and lack of appetite. In short, both metoclopramide and the clown’s mustard herbal combination worked well at reducing the symptoms of IBS.

However, side effects occurred more frequently and severely in the metoclopramide group. Given the lack of differences noted between the products at reducing symptoms of IBS, it would seem sensible to choose the treatment with the fewest reported side effects and no limits on duration of use.

Q. What evidence supports use of enteric-coated peppermint oil capsules for IBS?

A. Peppermint oil has been shown to relax intestinal smooth muscle. In Great Britain, peppermint oil is currently being prescribed for IBS by physicians and it has been used as a digestive aid and to soothe upset stomachs for generations.

Peppermint oil has also been studied for use in an important examination of the colon. A colonoscopy is a procedure of viewing the interior lining of the large intestine (colon) using a colonoscope, a slender, flexible, hollow, lighted tube about the thickness of a finger. A study published in the New England Journal of Medicine supports the idea that even people who are not at risk for colon cancer should have this test. The American Cancer Society recommends that men and women at average risk of colon cancer should have a colonoscopy every 10 years, beginning at age 50.

During a colonoscopy, individuals are sedated and almost no discomfort is experienced. The insertion of the colonoscope into the rectum and up through the colon causes some spasming. This is a natural and expected event and the physician performing the exam administers medications that effectively reduce the spasms.

A recent study compared the use of peppermint oil and commonly used medications to reduce the colonic spasming in colonoscopy. The peppermint oil was introduced directly into the colon. Effective reduction of colon spasming was observed in 88% of the patients.

In a critical review and meta-analysis of peppermint oil for irritable bowel syndrome published in The American Journal of Gastroenterology, eight randomized controlled trials were identified. The studies collectively showed peppermint oil is superior to placebo in improvement of the symptoms of IBS. Because of the good results of these trials, the authors of the review urged additional study of peppermint oil in IBS.

However, straight peppermint oil is rapidly absorbed into the blood stream from the stomach. In recent studies comparing enteric-coated peppermint oil capsules and non-enteric coated oil, both preparations provided effective symptom relief. However, the studies concluded the enteric-coated capsules delivered the benefit of the peppermint oil directly to the intestines. In the treatment of IBS, enteric-coated supplemental peppermint is most definitely preferred.

In fact, an enteric-coated peppermint oil capsule containing rosemary and thyme is extremely effective in the treatment of IBS. All three of these oils are classified as volatile oils, derivatives found in plants that impart taste and aroma. The combination of peppermint, thyme, and rosemary oils in enteric-coated capsules provides significant relief in IBS-related pain.

Q. Can clown’s mustard and other herbs be taken with enteric-coated peppermint oil?

A. Yes, peppermint oil capsules and clown’s mustard can be used together. However, depending on the symptoms, individuals with IBS may want to start with one supplement and then add the other if needed.

Q. How do consumers find these formulas?

A. Fortunately, herbal combinations containing clown’s mustard and enteric-coated peppermint oil capsules are both available at health food stores, natural product supermarkets, pharmacies, and from health professionals. Most knowledgeable sales personnel and health professionals can direct consumers to the most effective products.

Q. What should customers look for when purchasing peppermint oil?

A. As mentioned before, enteric coating of the peppermint oil is extremely important. The coating prevents the oil from being absorbed in the stomach. The enteric coated-capsule moves through the stomach to the small intestine and eventually to the colon, where it is released for maximum benefit.

Q. What is the dosage for peppermint oil?

A. The German Commission E approved peppermint oil for the treatment of irritable colon. In enteric-coated form, the Commission E recommends 0.6 ml per day. Enteric-coated peppermint capsules are available.

Q. Are there side effects or other contraindications?

A. Sometimes, the enteric-coated peppermint oil capsules may cause a transient burning sensation in the rectum when moving bowls. Reducing the dose will correct this.

Individuals who must refrain from alcohol should not take clown’s mustard in an herbal tincture, which may contain alcohol.

Q. What else can IBS patients do to feel better?

A. Food allergies or food intolerance may be associated with IBS. Dairy products and certain grains may trigger a painful episode of IBS. Determining those foods that initiate the problems and eliminating them from your diet can be very helpful.

Many people report their symptoms occur after a meal. Hyperactivity of the intestine of IBS is the response. Often, the strength of this response after a meal is in direct relation to the number of calories and he amount of fat in the meal. Reducing saturated fat, limiting calories, and increasing fiber intake may be helpful.

Stress also stimulates the intestinal hyperactivity. Relaxation training may reduce some IBS symptoms. Listening to therapeutic audiotapes, hypnosis, counseling, and biofeedback all have been shown to improve the healing response in persons with IBS.

Conclusion

IBS can be painful and frustrating, capable of causing much distress. While currently there is no cure for IBS, the symptoms can be managed. The pain, abdominal discomfort, and bowel problems of IBS all respond well to treatment with the use of key herbs, including clown’s mustard, and enteric-coated peppermint oil. These herbal combinations can be both effective and safe in treating IBS. Clown’s mustard and enteric-coated peppermint oil are both effective front-line natural alternatives for IBS treatment.



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Bio-Allers – All Natural Allergy Relief
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Date: March 12, 2007 02:50 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Bio-Allers – All Natural Allergy Relief

VitaNet is pleased to offer you the bio-allers ling of homeopathic allergy remedies. For over 15 years, bioAllers advanced allergy medicine has provided relief to allergy sufferers everywhere.

Allergies have become a common condition for a growing number of adults and children, affecting an estimated 50 million people in the United States. Every year, approximately 5.4 million unattended school and work days are lost due to allergies. Everything from the air we breathe to the food we eat can cause an allergic reaction, resulting in a number of annoying and often debilitating symptoms.

Approximately 35 million people suffer from seasonal allergic rhinitis, commonly known as hay fever, which is triggered by such allergens as week, tree, and grass pollens. Approximately 16.7 million office visits to health care providers each year are attributed to allergic rhinitis.

In addition to seasonal allergies, a growing number of people suffer from household allergies, including mold spores, yeast and dust mites. Avoidance of these reaction-causing substances is the most effective treatment for these allergies. However, that is not always easy or possible to do.

In four double-blind clinical trials, homeopathic allergen preparations allersodes were shown to relieve symptoms and reduce allergic reactions. Treatment groups were shown to have from 33% to 83% greater symptoms improvement than the placebo group. The most recent study showed that those patients who had been taking the allersodes continued to show reduced allergy symptoms for up to five weeks after the last does was taken.

bioAllers is a leader in the research and development of allergy relief and is the #1 homeopathic allergy relief brand. bioAllers also delivers specific allersodes that work with the body to deliver targeted symptom relief. bioAllers relieves allergy symptoms of sneezing, runny nose, itchy and watery eyes, congestion and headache without side effects or drowsiness.

References:

Janet zand, L.Ac., OMD, Allen N. Spreen, MD CNC, James B LaValle, RPH, ND, Smart Medicine for Healthier Living, 1999, P. 291-293.

Reilly D.T., Tylor M.A., McSharry C., Aitchisin T.C., Is Homeopathy a Placeby Response? Controlled Trial of Homeopathic Potency with Pollens in Hayfever as Model, The Lancet, October 18, 1986, 881-886.

Poitevin B., Review of Experimental Studies in Allergy, British Homeopathic Journal, April 1998, Vol. 87, PP. 89-99.



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Revita
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Date: March 08, 2007 12:27 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Revita

Revita, the most efficient hair growth stimulating shampoo available in the market is the final result of DS Laboratories efforts on cutting edge research. Revita is a powerful and unique SLS/SLES free combination of active ingredients specially designed to maintain scalp vitality and act on folicle dysfunctions in order to achieve best results in short periods of time. Sodium Lauryl Sulfate and Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers, are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, providing a high quality scalp skin safe shampoo product.

Revita was developed with a cost-no-object approach. Revita’s compounds have been chosen based exclusively on their properties, quality and efficacy (in the opposite of the majority of available products, which are usually developed with production costs in mind). The final result is a very high quality shampoo product with absolutely no equivalent competitor in the market. Revita combines costly first line compounds at high concentrations like Caffeine at 4.0%, Pyrus Malus (Apple) Seed Extract at 1.0% and Spin Traps (SOD Mimic) at 0.1% with other top level ingredients which make Revita a unique product in its class.

To improve the efficacy of this synergic combination, DS Laboratories developed a unique “chemical free” extraction process that keeps original properties and clinical efficacy of final components. Through gentle mechanical compression, Revita’s compounds are obtained as pure and chemically preserved active molecules.

Revita starts acting on your scalp and hair follicle since the first day of use. The time you will need to note the first results will depend of the severity and duration of your hair loss. No matter how long or how intense your hair loss is, using Revita on daily basis will improve the vitality of your scalp, maintaining the quality of your hair and stimulating new hair growth.

Through the synergic interaction of very effective compounds, Revita brings you a highly effective product designed to maintain scalp vitality and act on hair loss. By combining an antioxidant effect, anti-DHT properties, powerful hydrating molecules, hair growth stimulants and structural amino acids, Revita brings you the most effective hair growth stimulating shampoo available.

Apple Polyphenol (procyanidin B2 and C1) - phytochemical concentrate found in the skin of unripe apples that acts as potent antioxidant. It protects cells against free radicals, reactive atoms that contribute to tissue damage in the body. These chemical compounds are being studied extensively in labs around the world for their health effects in major diseases including treatment of hair growth. Studies showed that after sequential use, an increase of almost 80% of hair diameter and an increase in number of total hairs was shown, with no side effects.

In 2000, Japanese researchers presented their findings to the international community on the hair growth effects of apple polyphenols - specifically one known as procyanidin B-2. They identified two successful compounds- one from chardonnay grapes, and one extracted from unripe apples. The procyanidin B-2 fraction clearly outperformed the grape extract. "Procyanidin B-2 purified from apples," stated the research team, "shows the highest activity of more than 300% relative to controls."

In the same year, in a double-blind placebo-controlled trial, nineteen men with male pattern baldness were studied with a daily topical application of a 1% procyanidin B-2 solution, extracted from apples. Ten other balding men served as controls, receiving a placebo solution. After 6 months, the study concluded:

• The increase in number of total hairs and terminal hairs in the procyanidin B-2 group subjects was significantly greater than controls.

• 78.9% of subjects showed an increased mean value of hair diameter.

• "Procyanidin B-2 therapy shows promise as a cure for male pattern baldness."

Following the revelations, an attempt was made to further understand the mechanism by which the remarkable hair growth effects occurred. The results were published in the prestigious British Journal of Dermatology: Procyanidin B-2, extracted from apples, promotes hair growth: a laboratory study, Br J Dermatol. 2002 Jan;146(1):41-51. In this study, the researchers concluded that procyanidin B-2 acts to diminish protein kinase C isozymes, which play an important role in the hair growth cycle. Procyanidin B-2 seems to promote hair growth by down regulating PKC in both the anagen (active growth phase) and telogen (resting phase) of the hair follicle. When the anagen phase is prolonged, and the telogen phase is shortened, increased hair growth results.

Two more clinical trials and a total of seven published studies have now confirmed the surprising hair growth-promoting effects of apple procyanidins. Here is a summary of those findings:

• Total Number of Hairs: Significantly Increased

• Total Number of Terminal Hairs: Significantly Greater

• Increase in Hair Diameter: 78.9% Positive • Ratio of Thicker (terminal) Hairs: Significantly Higher

• Hair Follicle Activation: Intensive

In the most exciting development yet, Japanese researchers released a new study late in 2005. Once again, procyanidin therapy was proven successful in regrowing hair in subjects with male pattern baldness. The new study, published in the Journal of Cosmetic Dermatology, confirmed the findings of earlier studies, showing clear improvement in the number of hairs and the density of hairs in the treated area. Building on the success of earlier trials, the study was extended to 12 months in the procyanidin group, and proved that longer term procyanidin therapy was even more successful than prior 4 and 6 month trials.

Cooper Peptides - Cooper Peptides have two main properties: (1) potent tissue protective anti-inflammatory agents that limit oxidative damage after tissue injury, and (2) tissue remodeling activation agents, that is, the processes for removal of damaged protein and scar tissue and their replacement by normal tissue. Studies at numerous universities and research institutes have found copper-peptides to improve hair transplant success, increase hair follicle size, stimulate hair growth and reduce hair loss.

Research scientists at the University of San Francisco Wound Center stumbled upon very interesting results. Their discovery was made while applying a synthetically formulated compound, Copper Peptide, to severe wound areas on several patients. During this process something unusual happened. Not only did the wounds heal about 30 percent faster, but a significant stimulation of the follicular cells occurred. As a side effect, these tripeptide complexes actually grew hair around the wound area.

The discovery was so startling that they then applied the same Copper Peptide complex to a female patient who had suffered roughly 90 percent alopecia (hair loss) for years. After about six months of use, she had recovered almost 100 percent of her hair. Dr. Loren Pickart, the leading authority in Copper Peptide technology, describes it as being like a protein injection to the scalp.

Tests were then conducted with chemotherapy patients and recent hair transplant recipients, all with great success in stimulating newer and stronger hair follicles.

Spin traps – are very special compounds that were originally utilized in measuring free radical activity because they react with free radicals both in vitro and in vivo, producing stable complexes. The most commonly used spin trap and the standard which measures new ones is PBN - alpha-phenyl- N-tert butyl nitrone. Hundreds of studies have been conducted over the last ten years that have tested PBN and other “spin traps” in numerous conditions. Later it was discovered that these spin traps had powerful free radical quenching abilities in living systems and could treat a variety of conditions. Spin traps could provide unique protection against free radical damage that complements and enhances the activities of the classical antioxidants such as vitamin C and vitamin E.

Spin traps modulate NF kappa-B regulated cytokines and inducible nitric oxide synthases that are implicated in pro-inflammatory disease conditions. A method for ameliorating a cellular dysfunction of a tissue such as the treatment of hair loss and stimulation of hair growth comprises administering a nitroso or nitrone spin trap to the affected tissue. These agents inhibit the reaction of superoxide and nitric oxide to produce peroxinitrite. Scientists discovered that nitrone and nitroso spin traps have properties in the body for ameliorating cellular dysfunction in tissue attributed, in part, to high energy oxygen and hydroxyl free radicals, and enhancing recuperation of the tissue. Alpha-phenyl-N-tert butyl nitrone (PBN) can be administered, for example, as an anti-alopecia agent to stimulate hair growth.

Spin traps can be administered to the skin to be treated, such as the scalp. Depending on the type of hair loss or alopecia being treated and the conditions thereof, the stimulation of hair growth can usually be obtained by topical application, preferably repeated daily application. The utility of topically applied spin traps is not limited thereto, however, and the stimulation of hair growth can include an increased rate of growth, increased hair diameter, follicular neogenesis, and the like; inhibiting hair loss or alopecia from progressing.

Ketoconazole - Topical ketoconazole shows itself to have an anti-DHT binding effect in the scalp. Nevertheless, it is likely that ketoconazole exhibits other methods to its anti-hair-loss effect. One such theory of ketoconazole anti-alopecia effects may be on its activity upon the removal of sebum, a fatty substance that accumulates in the scalp around the hair follicles. In addition, ketoconazole is an antifungal medication and is significant for people combating hair loss since acting as an antifungal agent it reduces scalp irritation caused by fungal colonization or infection. Reduction of the inflammatory process that occurs in male pattern alopecia is crucial.

If we first examine the role of androgens, specifically dihydrotestosterone (DHT), we find that this hormone has been thought to slowly "choke" the growth of the hair follicle by inhibiting the function of an enzyme in the hair follicle called adenylate cyclase. Suffice it to say that when DHT concentrations remain high in the scalp, we see terminal (thick, coarse) scalp hair become reduced to vellus hair (fine, thin peach fuzz). On March 04, 2001, at the American Academy of Dermatology Meeting in Washington DC, scientists presented the findings of a study done on 1% ketoconazole shampoo which had good news for hair loss sufferers. In the study presented, one hundred male volunteers with mild to moderate dandruff and somewhat oily scalp, were using in a double-blind fashion either a 1% ketoconazole shampoo or a 1% zinc pyrithione shampoo, 2-3 times a week for 6 months.

Analysis of the different parameters set up in the study shows that the hair diameter gradually increased with ketoconazole use (+8.46%) over a 6 month period, whereas the diameter showed a trend to decrease with zinc pyrithione use over the same period (-2.28%). The sebum excretion rate was reduced with ketoconazole (-6.54%) while it increased with zinc pyrithione (+8.2%) over the same period of time. The number of hairs shed over a 24-hour period was reduced by 16.46% with ketoconazole and 6.02% with zinc pyrithione after 6 months. Finally, the percentage of hairs in the anagen phase increased by 6.4% and 8.4% respectively during the study.

The results are similar to a previous study done on 2% prescription strength Ketokonazole where it was shown that use of 2% ketoconazol yielded an increase in hair shaft diameter similar to what was achieved by the control group using 2% Minoxidil and a non-medicated shampoo.

Rooibos - Rooibos or Red Bush Tea - a hardy shrub indigenous to the North Western Cape of South Africa – is an exciting new botanical ingredient with potent antioxidant and anti-inflammatory properties well documented in medical literature. In alternative medicine Rooibos is often prescribed for nervous tension, allergies, stomach and digestive problems. Results from an independent study also showed a significant improvement in hair loss. Studies were initiated at an independent laboratory (Dermascan, France) to study the effect of the use of Rooibos in a hair lotion on a group of healthy persons who were suffering from the problem of hair loss. A 90 day trial was conducted comparing a hair lotion containing Rooibos with a placebo lotion.

After 90 days results showed a significant increase of the hair growth in the lotion containing Rooibos compared with the placebo. An increase in the hair growth was observed with 89% of the volunteers with no undesirable reactions (irritation or allergy). The participants were next asked to fill in a questionnaire. When the results were tallied, 67 percent rated their hair loss as zero or low, 78 percent saw a low to medium improvement, 45 percent saw a low to medium regrowth of hair, and 63 percent considered their hair had become smoother and shinier.

Conclusion: results show that most of the volunteers had a remarkable improvement in both the increase of hair growth and the decrease in hair loss.

MSM - Sulphur is present in protein-rich foods containing high levels of the amino acids methionine and cysteine. These foods include meat, fish, legumes, nuts, eggs, and vegetables, especially onions. However, sulphur has recently become a popular nutritional supplement and topical treatment thanks to the discovery of methylsulfonylmethane, or MSM.

The use of MSM as a nutritional supplement and topical application is relatively recent. An American chemist named Robert Herschler, began studying MSM in 1955. However, another man, Dr. Stanley Jacob with Oregon Health Sciences University in Portland, is considered by many to be the father of MSM. Dr. Jacob found that simple marine life like algae and plankton convert inorganic sulphur to organic sulphur compounds. These compounds are known as dimethylsulfonium salts. These salts are transformed into dimethyl sulfide (DMS), which is released into the atmosphere and is converted by ultraviolet light into dimethyl sulfoxide (DMSO). When DMSO oxidizes, it turns into MSM and is absorbed by plants that become food for animals and humans. MSM is a white, crystalline powder that is odorless and nearly tasteless. When taken as a dietary supplement, MSM proved to have the same health benefits as DMSO without side-effects such as bad breath, itchy skin, nasal congestion, and shortness of breath. Why does MSM help with the development of stronger hair? Various scientific studies have proven that MSM contributes a definite normalizing effect on body functions. The sulfur normally provided to the body by MSM is required for healthy collagen and keratin which are essential for healthy hair, skin and nails. MSM also has proven antioxidant benefits which can disrupt or alter damaging chain reactions of lipid peroxidation in the cell membranes.

MSM has been widely used as a dietary supplement without any reports of allergy or intolerance related to its use. Supplements of MSM are comfortably assimilated without side effects. There are no known contraindications.

Caffeine 4% - Active caffeine ingredient helps to regulate the effects of testosterone levels. Male pattern baldness is known to occur in individuals with sensitivity to testosterone, causing damage to hair follicles that eventually leads to baldness. Caffeine is a xanthine alkaloid compound that acts as a stimulant in humans. Caffeine is a central nervous system (CNS) stimulant, having the effect of warding off drowsiness and restoring alertness.

The independent study at the University of Jena used hair samples from the scalps of young men entering into the first stages of hormone-related hair loss. The study relied on a hair organ culture that used four different types of testing samples. The first was a nutrient-based sample, the second a testosterone only sample, the third was a caffeine only sample and the fourth a mixture of caffeine and testosterone.

According to the research, the results showed that the samples containing the caffeine nutrient helped to stave off hair loss and encouraged new hair growth, while the sample that relied on testosterone only led to increased hair loss. But perhaps the most impressive was the testosterone and caffeine sample, which helped to prevent further hair loss.

The results showed that using the caffeine treatment average growth was increased by around 46 per cent and the life cycle of the hair was extended by 37 per cent, when compared to the control study.

Carnitine Tartrate - L-Carnitine, a vitamin-like nutrient, occurs naturally in the human body and is essential for turning fat into energy. Active energy metabolism is an essential prerequisite for the growth of strong and healthy hair. In biological systems ATP acts as the universal energy currency. One of the most potent bio-actives that significantly increases cellular ATP content is carnitine tartrate.

Statistical evaluation demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate, showing that carnitine tartrate is an ideal ingredient for hair care formulations, providing energy for the optimal environment to produce strong and healthy hair. Throughout the test period ATP content within plucked hair follicles was determined twice daily using a commercially available test kit. Statistical evaluation of baseline adjusted values demonstrated a significant increase in ATP equivalents in human hair roots treated with carnitine tartrate. These effects were absent in the placebo group, thus underlining the stimulating activity of carnitine tartrate.

The outstanding bio-activity of carnitine tartrate was furthermore demonstrated in a second study, assessing the effects after a single application of a shampoo formulation supplemented with carnitine tartrate. Again, ATP levels in plucked human hair follicles were significantly increased.

Amino Acids: Ornitine, Taurine, Cysteine - Amino acids are the building blocks of protein, from which hair is created. They are assembled in the correct sequence by stem cells to form keratin, a complex and immensely strong hair protein. Vital amino acids have to be replaced consistently, as damage is accumulated over time. We can replace a combination of these lost amino acids directly into the hair, where they are shown to provide significant tensile benefits to the hair shaft.

Hair is composed primarily of proteins (88%). These proteins are of a hard fibrous type known as keratin. Keratin protein is comprised of what we call "polypeptide chains.” The word, polypeptide, comes from the Greek word "poly" meaning many and "peptos" meaning digested or broken down. In essence, if we break down protein, we have individual amino acids.

Many (poly) amino acids joined together form a "polypeptide chain". Two amino acids are joined together by a "peptide bond", and the correct number of amino acids placed in their correct order will form a specific protein; i.e. keratin, insulin, collagen and so on. The "alpha helix" is the descriptive term given to the polypeptide chain that forms the keratin protein found in human hair. Its structure is a coiled coil. The amino acids link together to form the coil and there are approximately 3.6 amino acids per turn of the helix (coil). Each amino acid is connected together by a "peptide bond". The peptide bond is located between the carbon atom of one amino acid extending to bond with the nitrogen atom of the next amino acid. In many individuals the extremities, including the top of the head, are the most difficult places to maintain blood flow. Follicles which are constantly deprived of blood, and therefore nutrients, cannot produce hair properly. Lack of proper nutrients, amino acids, minerals and vitamins can certainly hamper hair growth.

L-Arginine is a semi-essential amino acid synthesized by the body from L-Ornithine. Arginine + Ornithine support protein synthesis because they are involved in the transport and storage of nitrogen. The usage of taurine corrects the "rigidification" of the connective sheath that surrounds the Pilosebaceous unit and hair follicles, specifically those affected by pattern hair loss. This is a novel and previously undisclosed angle on hair loss treatment that has yet to be touched upon in any of the medical literature or prior publications.

The amino acid, l-cysteine speeds up hair growth and increases hair shaft diameter resulting in fuller hair. L-cysteine has been reported to facilitate longer hair growth, beyond what is genetically programmed. L-cysteine also provides potent antioxidant protection to the hair follicle. Users of topical n-acetyl-cysteine have reported hair regrowth.

Emu Oil - The emu, dromaius nova hollandiae, is a flightless bird part of a group called ratites which also includes the ostrich and the kiwi. Modern Australians learned early on from the Aborigines the many valuable qualities in the emu and its oil. The earliest research studies in emu oil come from Australia, and Australia continues to export emu oil to this day.

In the United States today there is a growing network of research labs interested in emus and their incredible oil. Emu oil is rendered from a thick pad of fat on the back of the bird that was apparently provided by nature to protect the animal from the extreme temperatures in its Australian homeland. Emu oil is deep penetrating and super hydrating to the skin - an all-natural tissue nutrient. Michael Hollick, MD, Ph.D., Professor of Medicine, Physiology, and Dermatology at Boston University School of Medicine conducted a study involving emu oil and hair growth. His study found that there was a 20% increase in growth activity of skin that received emu oil compared to skin that received corn oil. Looking at the hair follicles Dr. Hollick realized they were much more robust, the skin thickness was remarkably increased suggesting that emu oil stimulated skin growth and hair growth. Additionally, the study showed that over 80% of hair follicles that had been "asleep" were woken up, and began growing.

Emu oil is anti-inflammatory, which may be in part why it stimulates hair growth. Emu Oil has also been shown to be a 5 alpha reductase inhibitor in target tissues when topically applied, which likely contributes significantly to its hair growth properties. A third important property of emu oil is that it is bacteriostatic.

Emu Oil contains a multitude of Essential Fatty Acids (EFA) which helps to "feed" the skin. Consumers who suffer from natural forms of baldness have reported hair re-growth. Since Alopecia Areata only suppresses the hair follicle (vs. killing the hair follicle), emu oil may have an effect to assist with hair regrowth.

Biotin – Biotin is a member of the B-vitamin family and a major component in the natural hair manufacturing process -- it is essential to not only grow new hair, but it also plays a major role in the overall health of skin and nails. The beneficial effects of biotin on hair may be linked to its ability to improve the metabolism of scalp oils. Biotin when absorbed by the scalp may promote hair growth and it is able to penetrate the hair shaft making it expand which actually thickens the hair cuticle.

Biotin is used in cell growth, the production of fatty acids, metabolism of fats and amino acids. It plays a role in the Krebs Cycle, which is the process in which energy is released from food. Biotin is so important to hair health, that many dermatologists prescribe biotin supplements to their patients as part of their medical treatment for hair loss.

After applying Revita with a gentle massage, you should leave it on the scalp from 1 – 2 minutes before rinsing. Then repeat and leave on the scalp for 3 – 5 minutes. If desired, follow with a high quality conditioner. For optimal results, Revita should be used at least 5 times per week.

This formulation is contraindicated in individuals with a history of sensitivity reactions to any of its components. It should be discontinued if hypersensitivity to any of its ingredients is noted.

Q. Is Revita safe ?

A. Revita primarily contains compounds that are not only safe in topical use, but actually dramatically enhance overall skin health. The other active ingredients such as Ketoconazole have been tested in clinical studies and have been shown safe.

Q: Can I use hair sprays, mousses, gels, etc.?

A: Hair spray, gel, and other styling aids are not recommended since they tend to clog the hair shaft. However, you can use them while using Revita.

Q: Can I have my hair colored or permed while using Revita ?

A: While there is no evidence that coloring or perming hair can lead to or even worsen hair loss, it is generally not recommended for people with hair loss. If you are experiencing hair loss then perming and coloring hair is not recommended. However, this will not interfere with Revita.

Q: What is SLS/SLES free ?

A: SLS means Sodium Lauryl Sulfate and SLES means Sodium Laureth Sulfate, commonly used low cost detergents in shampoos and cleansers. They are linked to skin irritation, skin drying and hair loss due to follicle attack. Revita is Sodium Lauryl Sulfate and Sodium Laureth Sulfate free, and that means that Revita does not irritate you scalp and preserves your hair follicale health.

Q: Can I blow dry my hair after using Revita ?

A: Extreme heat damages the proteins in the hairs making them fragile. Nevertheless, if you need or want to blow dry your hair, you can do it after using Revita.

Q: Who is a candidate for Revita ?

A: Ideal candidate is someone with little hair loss or at the beginning stages of hair loss, since it is much easier to prevent hair loss then to grow new hair. Someone who is concerned with hair loss prevention should start using Revita immediately.

Q: What type of results should I expect with Revita ?

A: When deciding to use Revita, it is important to have realistic expectations. Depending of severity and duration of your hair loss, it could take some time to see hair growth. In fact, during the first 2 weeks of treatment you may actually notice increased hair loss as old hairs are being pushed out and the hair follicles start growing new hair. Do not become alarmed with this and just stick to the treatment.

Q. Does Revita have any systemic side effects ?

A. No, when used as directed, Revita active ingredients have a long history of use both orally and topically.

Q. Does Revita work for women?

A. Yes. In most cases, the cause of hair loss in women is surprisingly similar to men. Fortunately for women, estrogen helps to protect the hair follicle from the destructive effects of DHT. However, many women develop thinning hair and loss due to fluctuation of estrogen levels and/or over production of DHT. Revita can help protect the hair follicle from DHT resulting in a thicker, fuller and healthier hair.

Q. I am using other topical treatments. Can I use Revita at the same time ?

A. Yes. Revita has no side effects and does not cross react with other topical treatments. You can safely opt to use Revita with other products, and we strongly recommend the association with Spectral.DNC for more severe hair loss or Spectral.RS for thinning hair.

Q. Do I need to use Revita for a long time ?

A. Once you have reached the desired results, you should continue to use Revita as your regular shampoo to maintain the revitalized hairs and a healthy scalp.

Q: Is stress a factor in hair loss?

A: When the body is under significant physical and emotional stress it is possible that the immune system will produce anti-bodies that attack hair follicles, and this results in bald patches or diffuse loss. Stress-induced loss will respond very well to Revita and you should keep using Revita as your regular daily shampoo to keep your scalp healthy.

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What sets Sytrinol apart?
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Date: February 27, 2007 09:24 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: What sets Sytrinol apart?

While other cholesterol improving supplements fail to consistently deliver on their claims, Sytrinol has repeatedly succeeded in clinical studies. Some products say they are clinically proven, but the ingredient used in the trial is not available to the consumer. Furthermore, too often the effective dose used in the clinical trials is not the same dosage that is found in the supplement at retail. Sytrinol delivers the same ingredient at the same effective dose used in clinical trials.

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Benefits - Supports joint function and tissue health*
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Date: December 11, 2006 03:46 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Benefits - Supports joint function and tissue health*

To understand glucosamine's role, it is important to understand joint structure and function. Cartilage in the joints acts as a shock absorber to cushion the blows of daily wear and tear. Joint cartilage is made of a unique connective tissue that consists of collagen and proteoglycans. Collagen is a strong, fibrous, insoluble protein. Proteoglycans are large, carbohydrate-rich protein chains made up of 95 percent polysaccharides and 5 percent protein called glycosaminoglycans (GAGs). GAGs are composed of repeating two-sugar units (disaccharides) that contain glucosamine sulfate and other amino sugars. Surrounding the joint cartilage is synovial fluid, which contains many substances including its chief component, hyaluronic acid. Hyaluronic acid forms the backbone of other proteoglycans and is responsible for the thickness of synovial fluid as well as its lubricating and shock-absorbing properties. Synovial fluid also provides nutrients for the joint cartilage.

Glucosamine sulfate is a normal constituent of glycosaminoglycans in cartilage and synovial fluid. In essence, glucosamine sulfate provides important building blocks for cartilage production. Laboratory studies suggest that glucosamine may also function to stimulate production of cartilage-building proteins. It is also thought that the sulfate portion of the molecule contributes to the efficacy of glucosamine sulfate in the synovial fluid by providing the elemental sulfur needed for strengthening cartilage and aiding glycosaminoglycan synthesis. 1,2,3

Glucosamine sulfate has been the subject of research for over twenty years. Clinical trials as well as experimental studies have repeatedly supported the efficacy of oral glucosamine sulfate in supporting joint function. In one large open trial, over 1200 people took oral glucosamine sulfate for periods ranging from 36 to 64 days. In this multi-center trial, ninety-five percent of the subjects experienced greater joint comfort and increased mobility. The physicians reported "good" results in 59%, and "sufficient" results in 36%. Furthermore, the improvements in joint health lasted for up to three months after the glucosamine sulfate was discontinued. 3

Promotes optimal joint comfort, function and flexibility*

Boswellia serrata (Indian frankincense) has been used for centuries in the Indian Ayurvedic system of medicine to maintain healthy joints. Even today, this is one of the primary uses for this plant in Ayurvedic medicine. Boswellic acids have been shown to support healthy joint tissue, maintain circulation to joints, enhance joint mobility, and promote joint comfort in animal models without known side effects. 4

Boswellin® is an extract rich in boswellic acids. Boswellic acids are potent modulators of enzymes involved in leukotriene synthesis in vitro, promoting a healthy balanced production of these components of the immune system.5 Healthy leukotriene balance can lead to enhanced joint function. A human clinical study was conducted to assess the effects of supplementation with a formula containing Boswellia, Curcumin and other nutrients on joint function. In this double-blind placebo-controlled crossover trial, participants were randomly assigned to receive the herbal formulation or a placebo for 3 months. Following this 3-month period, the treatments were reversed for an additional 3 months. The results showed that while each group was receiving the herbal formulation, they had superior joint function and a greater sense of joint comfort when compared to the placebo groups.6 Other trials lend further support to Boswellia’s ability to promote healthy joint function.4,6,7

Curcumin is a potent antioxidant that has known free radical scavenging activity. This activity of Curcumin is thought to play a major part in its role as a joint protective nutrient. In fact, the numerous beneficial effects attributed of whole turmeric are thought to stem in large measure from the antioxidant properties of curcuminoids. Antioxidants neutralize free radicals, which are highly unstable molecules that can damage cellular structures through abnormal oxidative reactions. Curcumin is not toxic to cells, even at high concentrations. Pure Curcumin was shown to be less protective than a mixture of curcuminoids, indicating a possible synergism among the curcuminoids.8

Curcumin demonstrates several other in vitro effects linked to free radical scavenging. Curcumin scavenges nitric oxide, a compound associated with the body’s inflammatory response.9 Curcumin also demonstrates in vitro inhibition of certain enzymes involved in promoting inflammatory reactions in the body. Together these results strongly suggest that Curcumin is a potent bioprotectant with a potentially wide range of therapeutic applications.9,10,11

Preliminary human trials have assessed the therapeutic potential of Curcumin, with results that verify the traditional use of turmeric as an herb to enhance joint health. In a short-term double-blind, cross-over, comparative study, eighteen people were randomized to receive Curcumin (1200 mg daily) or an alternative therapy for two-week periods. The participants in the Curcumin groups were shown to produce measurable enhancements in joint flexibility and walking time.12 Research suggests that Curcumin and Boswellia work extremely well in combination to benefit joint health and mobility, as trials combining both nutrients have yielded highly positive results.

Bioperine-Nature’s Absorption Enhancer Boosts Nutrient Absorption*

Traditional Ayurvedic herbal formulas often include black pepper or long pepper as synergistic herbs. The active ingredient in both black pepper and long pepper is the alkaloid, piperine. Experiments carried out to evaluate the scientific basis for the use of peppers have shown that piperine significantly enhances bioavailability when consumed with other substances.13 Several double-blind clinical studies have confirmed that Bioperine® increases absorption of nutrients.14

Curcumin is known to be poorly absorbed in the intestinal tract when used on its own, thereby limiting its therapeutic effectiveness. Oral doses are largely excreted in feces, and only trace amounts appear in the bloodstream. However, a study has shown that concomitant administration of 20 mg of piperine with 2 grams of Curcumin was able to enhance Curcumin bioavailability by an astounding 2000%. 15 These results speak to the wisdom of including a small amount of Bioperine® in the formulation to ensure nutrient bioavailability.

Sustained Release – For lasting joint comfort and convenient dosing

To ensure that the body can utilize all of the joint health-enhancing nutrients effectively, Best Joint Support featuring ArthriBlend-SR™ has been designed to have a sustained release delivery system. The nutrients are released over a longer period of time, maximizing absorption and providing the comfort-enhancing properties in a sustained manner. This unique delivery system allows the product to be taken just twice daily while maintaining its efficacy throughout the day.

Safety

Suggested Adult Use: Take two tablets every 12 hours. Take 4 tablets daily.

Scientific References
1. Vidal y Plana, R.R., Bizzarri, D., Rovati, A.L. Articular cartilage pharmacology: I. In vitro studies on glucosamine and non-steroidal antiinflammatory drugs. Pharmacological Research Communications 1978; 10(6):557-569.

2. Tapadinhas M.J., Rivera, I.C. Bignamini, A.A. Oral glucosamine sulphate in the management of arthrosis: report on a multi-centre open investigation in Portugal. Pharmatherpeutica 1982; 3(3):157-68.

3. Vaz, A.L. Double-blind clinical evaluation of the relative efficacy of ibuprofen and glucosamine sulphate in the management of osteoarthrosis of the knee in out-patients. Current Medical Research and Opinion 1982; 8(3):145-149.

4. Kimmatkar N, Thawani V, Hingorani L, Khiyani R. Efficacy and tolerability of Boswellia serrata extract in treatment of osteoarthritis of knee--a randomized double blind placebo controlled trial. Phytomedicine. 2003 Jan;10(1):3-7.

5. Safayhi, H., Mack, T., Sabieraj, J., Anazodo, M.I., Subramanian, L.R., and Ammon, H.P.T. (1992) Boswellic acids: Novel, specific, nonredox inhibitors of 5-lipoxygenase. J. Pharmacol. Exp. Ther. 261(3), 1143-1146.

6. Boswellia serrata. Alternative Medicine Review Monographs – Volume One. 2002.

7. Kulkarni RR, Patki PS, Jog VP, Gandage SG, Patwardhan B. Treatment of osteoarthritis with a herbomineral formulation: a double-blind, placebo-controlled, cross-over study. J Ethnopharmacol. 1991 May-Jun;33(1-2):91-5.

8. Majeed, M., Badmaev, V., Shivakumar, U., Rajendran, R. Curcuminoids: Antioxidant Phytonutrients. 1995. Piscataway, NJ: NutriScience Publishers.

9. Snow, J.M. Herbal Monograph: Curcuma longa L. (Zingiberaceae). The Protocol Journal of Botanical Medicine, Autumn 1995:43-46.

10. Rao, S., Rao, M.N.A. Nitric oxide scavenging by curcuminoids. J Pharm. Pharmacol. 1997;49:105-7.

11. Ramsewak, R.S., DeWitt, D.L., Nair, M.G. Cytotoxicity, antioxidant, and anti-inflammatory activities of Curcumins I-III from Curcuma longa. Phytomedicine 2000;7(4):303-308.

12. Deodhar, S.D., Sethi, R. Srimal. R.C. Preliminary study on antirheumatic activity of curcumin (diferoyl methane). Indian J Med Res 1980;71:632-34.

13. Atal, C., Zutshi, U., Rao, P. Scientific evidence on the role of Ayurvedic herbals on bioavailability of drugs. Journal of Ethnopharmacology 1981;4:229-232.

14. Bioperine®–Nature's Bioavailability Enhancing Thermonutrient. Executive Summary. 1996; Sabinsa Corporation, Piscataway, N.J.

15. Shoba, G., et al. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica 1998;64(4):353-6.



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for Great Joint Health buy Best Joint Support at Vitanet

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Q. How did research discover maitake’s health benefits?
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Date: November 22, 2006 01:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Q. How did research discover maitake’s health benefits?

A. Because maitakes are well known as healthy food, researchers interested in medicinal mushrooms have studied them extensively. They discovered many maitake compounds with dramatic health-promoting potential. One of these compounds, maitake D-fraction, has particularly powerful anti-cancer effects.

In lab studies, D-fraction stops the growth of cancer cells and cancerous tumors. Maitake D-fraction stimulates the activity of two white blood cells, macrophages and natural killer cells. These white blood cells then trigger the production of interleukins and other lymphokines, two biochemicals that help mediate the immune response. Maitake also inhibits some of the mechanisms that promote metastasis, or spread, of cancer cells in the lymph system and bloodstream.

Because of this success, maitake D-fraction is now being used in preliminary clinical trials of women with breast cancer. One study has reported significant improvement of symptoms, including reduction of the tumor. The maitake D-fraction was given to breast cancer patients in addition to standard chemotherapy.

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Pycnogenol: Heart, Blood Sugar and Cellular Health
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Date: November 03, 2006 12:16 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pycnogenol: Heart, Blood Sugar and Cellular Health

Pycnogenol (pronounced pic-nojen-all) is a natural plant extract originating from the bark of the maritime pine that grows along the coast of southwest France. Pycnogenol® consists of particularly bioactive flavonoid species and its purity is in strict accordance with the United States Pharmacopoeia. Pycnogenol® was initially developed 35 years ago in Europe. During the past years it evolved as one of the most thoroughly researched nutritional supplements, with over 200 studies published in peer-reviewed journals. Seventy of these studies were clinical with in total more than 4,000 patients. Pycnogenol® taken in dosages from 25mg to 300mg is well tolerated and Pycnogenol® was attributed “generally recognized as safe” (GRAS) by the FDA.

Pycnogenol® supports healthy capillaries

The “Career” of Pycnogenol® began in Europe, where it was first used to maintain vein and capillary health. Pycnogenol® has been shown to strengthen blood vessel walls, with 15 clinical trials showing fast relief from ankle and foot discomfort. A recent study with 200 passengers on long-haul flights showed that Pycnogenol® taken before departure and again during the flight supports foot comfort and healthy circulation. Travelers typically comment that with Pycnogenol® it is much easier to put shoes on again upon arrival. Clinicians in Germany discovered that Pycnogenol® also supports healthy capillaries in the eyes. Retinal capillaries may be affected by imbalanced blood sugar levels. In a multi-center field study with 1169 subjects Pycnogenol® supported healthy capillaries in the retina and improved visual acuity to some extent.

Pycnogenol® benefits the cardiovascular system

More detailed investigation of the interaction of Pycnogenol® with blood vessel walls at the University of Florida, Tampa led to an amazing discovery. Pycnogenol® stimulates an enzyme in blood vessel walls that is responsible for generating the most important vascular mediator, known as “nitric oxide” (NO). NO triggers relaxation of the arteries and supports clear blood flow. Hence, NO is the body’s mediator for maintaining healthy blood pressure levels and circulation. NO plays such an important function for cardiovascular health that Dr. Louis Ignarro (UCLA) and his co-workers received the Nobel Prize for this discovery in 1987.

A number of factors, including aging, can interfere with the body’s efficient production of NO. Supplementation with Pycnogenol® for four weeks was shown to restore NO production and improve blood supply to the fingertips of elderly people in a Japanese study. Microscopic evaluation of blood vessel diameter at the root of fingernails showed an increased diameter of capillaries allowing better blood perfusion. Specific sensors applied to the legs showed increased oxygen and decreased carbon dioxide presence. Better blood, nutrient and oxygen supply with Pycnogenol® benefits everybody. Italian researchers were able to show that regular intake of Pycnogenol® helps defy muscle cramps and minor pain in athletes.

The relaxation of arteries has a favorable effect on blood pressure. In two clinical studies Pycnogenol® taken for at least eight weeks was found to significantly support normal blood pressure.

Pycnogenol® stimulated NO generation directly translates into clear blood flow. This was first demonstrated at the University of Arizona, Tucson in smokers. Pycnogenol® dose-dependently, starting at a single dose of 25mg, countered the typical effects of cigarette smoking on the blood. Also, Italian vascular specialists found that Pycnogenol® supported the circulation of individuals on flights between New York and London.

Pycnogenol® supports healthy blood sugar levels

Pycnogenol® can support normal glucose levels when taken as part of a healthy diet and lifestyle plan. A clinical investigation has confirmed the significant glucose-lowering effect of Pycnogenol®. It was noted that Pycnogenol® did not affect insulin levels. Pycnogenol® appears to facilitate previously insulin-resistant cells to uptake sugar from the blood stream by yet unknown mechanisms.

Pycnogenol® limits cellular irritation

Two clinical studies carried out in Germany this year with student volunteers demonstrated that Pycnogenol® has a potent effect in preventing cellular irritation. Pycnogenol® inhibits a molecular “main-switch” in immune cells that triggers the onset of cellular irritation in any part of the body. Moreover, Pycnogenol® was found to inhibit so-called COX enzymes, which are involved with minor pain-sensation related to cellular irritation.

Pycnogenol® sooths menstrual pain

Japanese gynecologists discovered in 1999 that regular supplementation with Pycnogenol® soothes the normal discomfort of menstrual pain, particularly during cramping. Another clinical investigation of 47 women in year 2004 confirmed the effect of Pycnogenol® in addressing menstrual pain. This year a double-blind, placebo-controlled, multi-center field study with 116 women again confirmed these results. Pycnogenol® is not suitable for on-demand relief during menstruation. The studies show that Pycnogenol® reached highest efficacy when taken regularly for months.

Pycnogenol® helps to support respiratory health

Challenges to normal respiratory function may result from incidents the immune system perceives as harmful. Pycnogenol® offers valuable help in supporting respiration due to its immune-modulating effect and its ability to limit cellular irritation. A study at the University of Arizona found that Pycnogenol® supports clear breathing and lowers mediators of cellular irritation in the blood stream. More recently, a placebo-controlled clinical study at the University of California, Loma Linda described how Pycnogenol® supported healthy respiration in 60 children aged 6-18 years. Pycnogenol® needs to be taken continuously for prolonged periods of time for maximum benefit to the respiratory system.

Pycnogenol® is investigated in clinical trials all over the world. New findings are posted on the website www.pycnogenol.com.

Frank Schonlau Ph.D. is a biochemist who has spent nine years in medical research at the University Clinic of Munster Germany. His area of expertise covers vascular disorders, inflammation and dermatology. He has published more than 20 studies and review articles in the medical literature. Since entering the dietary field in 1999 he was involved in numerous studies on Pycnogenol® and communication of new health discoveries.

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Slimaluma Plus – Appetite Control
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Date: August 29, 2006 01:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Slimaluma Plus – Appetite Control

Slimaluma Plus – Appetite Control with Green Tea and Yerba Mate

 

Now Vitamins Slimaluma plus contains a proprietary standardized extract of Caralluma fimbriata—a succulent, edible cactus that grows native throughout India. It has been used for thousands of years, and most recently has become the subject of great interest based on its role in supporting and establishing more healthy eating patterns. Controlled clinical trials have showcased the extract’s ability to inhibit hunger sensory messages between the stomach and brain, while improving the rate at which the body synthesizes fat. By addressing these factors associated with unhealthy body weight, Now Vitamins Slimaluma Plus offers two-tiered support for anyone trying to rediscover a firm, fit physique.

 

Here’s how it works. As the stomach fills, it sends a signal to the brain’s hypothalamus region, letting it know that it is time to stop eating. Slimaluma is rich in naturally occurring compounds known as pregnane glycosides that interfere with the timing of this signal. This, in the eyes of researchers, is what causes users to experience feelings of fullness, even if they have not eaten. Slimaluma has also been shown to inhibit the formation of two enzymes involved in fat synthesis, allowing the body to convert more fat into energy, while sparing vital muscle proteins.

 

Now Vitamins Slimaluma Plus is a non-thermogenic, stimulant-free dietary supplement that is idea for individuals working to achieve a healthy body weight by establishing better eating habits.

 

  • Clinically shown to help support healthy weight management
  • Contains proprietary standardized extracts from Caralluma fimbriata
  • Manufactured without any chemical alterations to the herb’s key constituents
  • Has been consumed without adverse side effects for thousands of years*

 

Slimaluma is a trademark of Bencor Pacific, Inc.

 

 

* these statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

 

 



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Remifemin symptomatic relief, scientifically supported*
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Date: August 26, 2006 02:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Remifemin symptomatic relief, scientifically supported*

Remifemin

 

Symptomatic Relief, Scientifically Supported*

 

The only RemiSure black cohosh

 

Unique to Remifemin® - Exclusive standardized isopropanolic black cohosh extract, subject of over 90 scientific papers.

Proven Effective – The most clinically studies natural intervention for menopausal symptoms with over 40 years of use worldwide*

 

  • Relief from hot flashes, night sweats, mood swings, irritability, and related occasional sleeplessness*
  • Particularly in women in early stages of menopause*

 

Safe – Completely hormone free

 

  • Works naturally without plant-based estrogens that can affect breast and uterine cell growth
  • Can be used safely by women with a history of breast cancer who cannot take estrogen

 

Efficacy

STUDY DESIGN

BENEFITS

DOSAGE

REFERENCE

1. Twelve-week, randomized, multicenter, double-blind clinical trial comparing the efficacy and tolerability of Remifemin® in the treatment of climacteric complaints compared with placebo.  The primary efficacy measure was the change from baseline on the Menopause rating Scale 1.

·          Remifemin® effectively relieved menopausal symptoms, particularly in women in the early stages of menopause*

·          Most significant reduction was in hot flash occurrence*

·          Other symptoms resulting in significant reduction include: psyche (irritability and memory), and atrophy (vaginal dryness)*

·          No significant adverse effects reported

40mg qd

Osmers R, et al. Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms.  Obstet Gynecol. 2005 May; 105(5):1074-83.

2. A review of 29 randomized controlled trials of complementary and alternative therapies for menopausal symptoms.

·          Black cohosh is one of the only herbal remedies shown to be effective for menopausal symptoms, especially hot flashes*

 

Kronenberg. F. Fugh-Berman A. Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials. Ann Intern Med. 2002 Nov 19;137(10:805-13.

3. Four-week, pilot study, open clinical trial of menopausal women with hot flashes, including women with a history of breast cancer.

·          Remifemin® reduced mean daily hot flash frequency by 50% after 4 weeks*

·          Overall, participants reported less trouble with sleeping, less fatigue, and fewer night sweats* 

·          No participants stopped therapy because of adverse effects

40mg qd

Pockaj BA, et al. Pilot evaluation of black cohosh for the treatment of hot flashes in women.  Cancer Invest. 2004;22(4):515-21

4. Double-blind study involving the use of Remifemin® in women ages 43 to 60 with menopausal complaints lasting 6 months.

·          Majority of woman saw a 70% reduction of physical and emotional symptoms after 12 weeks, including hot flashes, night sweats, mood swings, and irritability*

·          Significant improvement was noted after 4 weeks use*

·          Remifemin® works safely and effectively to treat menopause symptoms without affecting hormone levels or vaginal cytology (pap smear)*

40mg qd

Liske J, et al. Physiological investigation of a unique extract of black cohosh (Cimicifugae racemosae rhizome): a 6-month clinical study demonstrates no systemic estrogenic effect. J Womens Health Gend Based Med. 2002 Mar; 11(2): 163-74

5. Double-blind, 6 month study in hysterectomized women under 40 with at least one ovary.

·          As effective as estriol, conjugated estrogens, or hormone combinations at decreasing physical menopausal symptoms at 4, 8, 12, and 24 weeks*

4mg dry extract bid (equivalent to 2 tablets Remifemin® bid

Lehmann-Willebrock E, Riedel HH. Clinical and endocrinologic studies of the treatment of ovarian insufficiency manifestations following hysterectomy with intact adnexa. Zentralbl Gynakol. 1988; 110(10):611-8

 

6. Women aged 45 to 58 with menopausal complaints were studied in a double-blind, 12 week, placebo-controlled trial.

·          Remifemin® decreased physical symptoms of menopause by approximately 60% (Kupperman menopausal indeed)*

·          Daily hot flashes decreased by 86% in the Remifemin® group(from 4.9 to 0.7 per day)*

·          Emotional complaints were also dramatically reduced*

4mg dry extract bid (equivalent to 2 tablets Remifemin® bid

Stoll W. Phytopharmacon influences atrophic vaginal epithelium: Double Blind study – Cimicifuga vs. estrogenic substances. 1987.

 

Safety

STUDY DESIGN

BENEFITS

DOSAGE

REFERENCE

7. in vitro, MCF-7 cell culture model to determine estrogen-agopnist and antagonist activity of commercially available herbal menopause preparations containing red clover, soy black cohosh, or a combination of herbs.

·          Remifemin® had no effect on estrogen-sensitive cells in vitro.

·          Results suggest safety for women with a history of breast cancer who cannot take estrogen.

In Vitro(10^3-10^5 dilutions)

Bodinet C, Freudenstein J. Influence of marketed herbal menopause preparations on MCF-7 cell proliferation.  Menopause. 2004 May-Jun;11(3):281-9.

8. Six-week, in vivo investigation of Remifemin®’s ability to stimulate estrogen-receptor positive cells in an animal model

·          No estrogen stimulating effects were found.

·          Prolactin, follicle-stimulating hormone, and luteinizing hormone levels were unchanged.

0.714m 7.14 or 71.4mg/kg/day

Freudenstein J, et al. Lack of promotion of estrogen-dependent mammary gland tumors in vivo by an isopropanolic Cimicifuga racemosa extract. Cancer Res. 2002 Jun 15;62(12):3448-52.

 

 

 

9. Comprehensive review examining all published literature pertaining to pre-clinical and clinical safety of various forms of Cimicifuga racemosa, as well as FDA and World Health Organization (WHO) adverse event reporting systems, monographs, compendia, internal unpublished data from a major manufacturer, foreign literature, and historical, anecdotal report.

·          Uncontrolled reports, postmarketing surveillance, and human clinical trials of more than 2,800 patients demonstrate a low incidence of adverse events (5.4%).

·          Of the reported adverse events, 97% were minor and did not result in discontinuation of symptoms, and the only severe events were not attributed to Cimicifuga treatemtn.

·          Confirms the safety of specific Cimicifuga extracts, particularly isopropanolic preparations (Remifemin®), for use in women experiencing menopausal symptoms and as a safe alternative for women in whom estrogen therapy is contraindicated *.

Various

Low Dog T, et al. Critical evaluation of the safety of Cimicifuga racemosa in menopause symptom relief. Menopause: Journal of the North American Menopause society. 2003;10(4):299-313.

 

Relevant Reports and Guidelines

ORGANIZATION

PUBLICATION

EXCERPT OF KEY CONTENT

American Botanical Council

The ABC Clinical Guide to Herbs including a black cohosh monograph issues September 2002

“Of 10 clinical studies, including a total of 1,371 participants, nine of these studies demonstrated positive effects for menopausal symptoms.  Numerous clinical trials with varied methods and designs have been conducted on the standardized isopropanolic/ethanolic extract of black cohosh root, Remifemin®, from 1981 to the present.”

National Institute of Health

Questions and Answers About Black Cohosh and the Symptoms of Menopause issued October 2002

“Other preparations of black cohosh have been less well studied than Remifemin® …black cohosh is used primarily for hot flashes and other menopausal symptoms.  A number of studies using various designs have been conducted to determine whether black cohosh affects the menopausal symptoms… To provide more definitive evidence on the effects of black cohosh on menopausal symptoms, NCCAM is funding a 12-month, randomized placebo controlled study to determine whether treatment with black cohosh is effective in reducing the frequency and intensity of menopausal hot flashes.”

The North American Menopause Society

Alternatives to Hormone Replacement Therapy: Suggestions for the North American Menopause Siciety issued July 2002

Reseach suggests that mild hot flashes can be relieved by consuming a serving of soy foods daily or taking a supplement of black cohosh.”

 

Responding to the need for alternative menopausal symptom relief*

 

Natural, Safe alternative to HRT for menopausal symptoms*

 

  • Remifemin black cohosh was as effective as HRT for menopausal symptoms*

 

Superior Manufacturing Quality

 

  • Prepared according to Good Manufacturing Practice (GMPs) which ensure delivery of a product with the highest quality and consistency
  • Convenient dosing – one 20mg tablet twice a day (one in the MORNING, one in the EVENING)
  • 100% RemiSure black cohosh – not a combination of herbs

 

VitaNet Recommends Remifemin

 

  1. Remifemin unique standardized isopropanolic extract is the most widely studied and clinically tested natural alternative treatment for relief of menopausal symptoms.
  2. Remifemin black cohosh proven effective in reducing menopause and peri-menopause symptoms, including hot flashes, right sweats, mood swings, and irritability without estrogenic effects.
  3. Used safely by millions of patients worldwide for over 40 years.  Remifemin has been proven effective and is the most clinically studied natural intervention of menopause.
  4. Remifemin doesn’t have the side effects that are experienced with hormonal drugs prescribed for the relief of menopausal symptoms.

 

Lit source: Enzymatic therapy.

*this statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treate, cure, or prevent any disease.



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EczeMate from Source Naturals
TopPreviousNext

Date: August 01, 2006 11:59 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: EczeMate from Source Naturals

Dr. Andrei Nedostupenko, a Russian heart surgeon, found that his hands were irritated by the constant washing he had to do prior to surgeries.

Then he remembered hearing about a distant relative’s recipe—a skin ointment unknown outside a small town in Russia. He tried it and the results amazed him. As a doctor, he wasn’t content to just enjoy his newlyreplenished skin; he began extensive investigations to discover the ointment’s secrets. After years of clinical trials, and great success, he is now bringing this formula to North America.

Source Naturals is pleased to bring you ECZEMATE, an amazing, replenishing formula from Russia. Made with natural ingredients free of pollutants, petrochemicals, or hazardous substances, it soothes,lubricates, and rejuvenates the skin.

From Russia?

Russia might not be the first place that comes to mind when imagining the source of a secret remedy for smooth, silky, supple skin, but in many ways it makes sense. With centuries of hard physical labor, intensely cold, bitter winters, and until recently, little access to the famous skin treatment centers of Europe or to modern cosmetics, who better than the Russians to appreciate a soothing cream that replenishes skin cells?

Natural Ingredients

The ingredients of ECZEMATE are natural ingredients that could be found in many farms and forests worldwide: beeswax, animal fats, fatty acids, rose hips, vitamin C, and carotenoids. The harvesting of many of these ingredients follows centuries- old folk traditions, the local knowledge of when certain plants reach their highest peak of potency. The secret to the ointment is the combination of the ingredients in a particular order at particular times, temperatures, and conditions.

Potent Herbs

ECZEMATE is a revitalizing and soothing ointment. One of the ingredients, rose hip oil, is a rich source of vitamins A, C and E, flavanoids, and other bio-active compounds, as well as essential fatty acids, including the Omega 3 group. It is thought that because the components of rose hip oil are so similar to those of skin cell membranes, that is why this oil has such powerful regenerative effects on skin cells. Composed of oleic (15-20%), linoleic (44-50%) and linolenic (30-35%) fatty acids, this amazing oil has been used effectively in worldwide skin tests.

Part of a Complete Skin Care Plan

For healthy skin in general, researchers recommend using zinc to support the immune system. Drink plenty of water, increase your intake of dark, leafy greens like kale and chard—both non-dairy sources of calcium—and make sure you are getting sufficient vitamin C. Avoid refined sugar, and replace animal products with fatty fish, such as salmon, herring, halibut and mackerel, to provide essential fatty acids.

Source Naturals is pleased to bring you ECZEMATE, an easy-to-use topical ointment that has had tremendous success in supporting smooth, healthy, silky skin. Unlike many skin formulas, it is made with natural products; it contains no corticosteroids, hydrocortisone, nor paraffin.

Use it as part of your own wellness program, taking charge of your own health and well-being in the wellness revolution.

References: www.wholehealthmd.com/refshelf/substances, visited 7/11/05 www.childhood-eczema.com, visited 7/20/05 Chopra, RN et al.1986.Glossary of Indian Medicinal Plants www.acne-advice.com/products/skincare /rosa_mosqueta/index.shtml, visited 6/21/05 Moreno, JC. 1990. Med Cutan Ibero Lat Am 18(1):63-66.

Angeles, AM, et al. 1990. J Invest Dermatol 94:504A.

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7-Syndrom Healing and 5-HTP
TopPreviousNext

Date: June 07, 2006 03:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: 7-Syndrom Healing and 5-HTP

Boomer Breakthrough – Keeping in the Game

If there is not thing boomers need to manage, its chronic stress. That’s because of its deleterious effects, which include accelerated aging and altered brain function. This month boomer breakthroughs will focus on 5-hydroxytryptophan or 5-htp, one of the most versatile and powerful anti-aging remedies. For starters, 5-htp is a more powerful antioxidant than either vitamin C or melatonin. This it deserves a place in ones daily vitamin regimen based on this fact alone. However, the better-known attribute of 5-htp is its stabilizing effects on the brain and nerves.

Mood, Anxiety and Depression

Chronic stress can lead to mood swings, anxiety, depression, poor memory, and reduced cognitive functions. Last month we recommended the Adaptogenic herbs Ashwagandha and Rhodiola as therapy for smoothing out periods of intense stress such as looming deadlines. For longer term stress supplementation with 5-htp is a better choice. That’s because extended periods of stress reduce brain levels of serotonin. Supplemental 5-htp is produced from the African plant Griffonia Simplicifolia and has over 30 years of safety and effectiveness in clinical use.

How do you know if you have low levels of serotonin? Persistent anxiety is one key and insomnia is another. 5-htp, an intermediary metabolite of serotonin, has proven to be clinically effective in reducing these disorders. Weight gain and eating disorders also appear to be associated with low serotonin levels.

Serotonin the Antiaging Neurotransmitter

Serotonin, one of three major neurotransmitters, has a calming effect and helps keep emotions in check. It has been extremely helpful in lessening panic attacks, various phobias, suppressing appetite, and reducing aggression, anxiety, and pain sensation. And, it may be more effective in relieving mild depression than antidepressants. In a 1991 Swiss study, the effectiveness of 5-htp in alleviating depression was compared to a conventional antidepressant, fluvoxamine (Luvox). Patients were divided into two groups and given either 100mg 5-htp or 150mg of fluvoxamine three times a day for six weeks. At the end of the test period, the 36 5-htp patients showed a greater percentage of improvement than the 33 fluvoxamine patients.

Other studies have compared 5-htp with antidepressants such as chloripramine and imipramine. 5-htp was at least as effective if not more so than the conventional drugs. Moreover, 5-htp has no reported side effects, although some patients have experienced mild nausea when they first take 5-htp. If this happens, merely back off and reduce the daily dose to 50mg and gradually increase it over a four-day period.

5-htp has an advantage over its precursor amino acid L-Tryptophan (LT). it is more readily absorbed than LT and is immune to meals without reducing its effectiveness. 5-htp, unlike LT, is not shunted into niacin, melatonin, picolonic acid and other amino acids. Seventy percent of oral 5-htp ends up in the bloodstream, crosses into the brain and is directly converted into serotonin.

It’s best not to combine 5-htp with antidepressant medications, although there have been no reports of adverse events. Suggested doses is 100mg 3 times a day or 200 to 200 mg taken at bedtime for insomnia.

Pain, Per-menopause and PMS

5-htp has additional benefits for boomers. It reduces hot flashes and is an effective anti-pain remedy. The concern over use of hormone replacement therapy (HRT) has led to interest in safe and effective methods of reducing hot flashes. Come anti-depressants (Prozac, ect.) have been effective in alleviating hot flashes in women with breast cancer or at risk of the disease. Increasing serotonin is the proposed mechanism by which this occurs. Serotonin in turn resets the brain’s heat regulating system. 5-htp is effective at raising serotonin levels, is free of side effects, and is an effective substitute for anti-depressants.

Additionally, 5-htp has been clinically useful in reducing premenstrual dysphoric disorder (PMDD) symptoms such as sadness, hopelessness, self-deprecation, tension, anxiety, emotional instability, tearfulness, anger and irritability.

Migraine and fibromyalgia share a common root in serotonin and adrenal hormone (Cortisol) receptor function. Serotonin plays a role in maintaining pain thresholds, vascular constriction/dilation and maintenance of restorative sleep. It is also thought to disrupt pain signals and induce the activity of endorphins, the brains natural painkiller.

Italian researchers report in two clinical trials involving patients with fibromyalgia, that 5-htp (100mg 3X/day) significantly reduced fibromyalgia symptoms. These include a number of tender points, subjective pain severity, morning stiffness, sleep patterns, and anxiety.

Now offers 5-htp in three convenient doses; 50mg for starters, 100mg for maintenance, and 200mg plus 250mg tyrosine, Niacinamide and vitamin B-6 to stabilize adrenal function and help control minor pain.

Adapted from 7-syndrome healing: Supplement essentials for Body and Mind by Marcia Zimmerman and Jayson Kroner, 2006, Nutrition Solution Publications.



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The unique clinical benefits of Sun Chlorella
TopPreviousNext

Date: March 25, 2006 12:34 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: The unique clinical benefits of Sun Chlorella

Over the years, Sun Chlorella Corporation has been sponsoring true clinical trials, carefully designed and carried out according to current conventional methodologies used in the pharmaceutical industry for drug development and testing. These “double-blind” clinical trial studies have greatly contributed to the substantiation of why Chlorella pyrenoidosa is so widely recognized within the scientific, alternative, and medical communities. With documented positive findings that have been discovered through ongoing research, you can be sure you’re getting the best top quality products with Sun Chlorella.

Unique Clinical benefits.

According to human immunology expert Randall E. merchant, PH.D. of Virginia Commonwealth University, in Richmond, Virginia, Sun Chlorella and Wakasa Gold (Liquid Chlorella) may be helpful to those suffering from a number of serious health problems because of the many unique clinical benefits found naturally in this supper food. Dr. Merchant states that many who suffer from chronic illnesses, “are known to have nutritional deficiencies…and when proper nutrition returns, some of the symptoms and problems dissipate. Such individuals can benefit from the superlative nutritional powers of Sun chlorella.” The four principal components of Chlorella pyrenoidosa that have been shown to have certain health benefits include chlorophyll, the fibrous cell wall, beta-carotene, and the powerful chlorella growth factor (CGF).

Some of the clinical investigations completed by Dr. Randall E. Merchant and a team of physicians at the university have included fibromyalgia, ulcerative colitis, and hypertension. Their primary focus was on the potential benefit of dietary supplementation with Chlorella Pyrenoidosa to help improve quality of life, and normalize body functions in patients with these types of chronic illnesses. All the subjects in each of the clinical studies suffering from either fibromyalgia, ulcerative colitis, or hypertension, consumed 10 grams of chlorella pyrenoidosa in tablet form and 100 ml of liquid chlorella every day for two to three months.

Chlorella – Excellent for Everyone

Dietary supplementation with Chlorella pyrenoidosa has had a beneficial effect in many of the people who participated in the individual clinical trial studies. Dr. Merchant’s research suggested that adding Chlorella pyrenoidosa (a natural whole food) to the diet, rather than relying solely on pharmaceutical drugs may be extremely beneficial to those who are dealing with serious health issues, and those who want to stay healthy.

Everyone – young and old, healthy and ill – can benefit from Sun Chlorella’s purification abilities, natural defense protection, and wholesome nutrition. Sun Chlorella does so by purifying, nourishing, and protecting your body so your own natural defenses are able to work more efficiently. This is clearly a super food that should be a part of everyone’s diet.

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Viterol A - Viatrozene gel 16% - reduce the signs of aging!
TopPreviousNext

Date: February 25, 2006 02:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Viterol A - Viatrozene gel 16% - reduce the signs of aging!

Viterol. A® is the latest weapon in the fight against the signs of aging that is taking America by storm. This breakthrough anti-aging compound is the result of 15 years of research into the effects of skin aging. DS Laboratories nanosome technology allows the delivery of active ingredients deeper into the skin and therefore achieves similar results to injection therapy. To learn more about DS Laboratories nanosomes click here. In an industry filled with empty promises and gimmick products, Viterol.A® is unique formulation that visibly lifts, firms, and boosts collagen production to keep skin young and healthy. Unlike many creams that make empty promises, Viterol.A® developed by DS Laboratories is backed by years of research, is rigorously tested, and is supported in clinical trials.

Clinical studies conducted on women between 25 and 54 years of age showed that after a 4 week period Viterol.A® produced:

Dr. Michael J, Bornstein, MD, PhD of the Medical Research Consultants of NY agrees that Viterol. A® is a remarkably effective topical lotion available for the treatment of the signs of aging by lifting the skin, removing age spots, and reducing the appearance of wrinkles. Dr. Bornstein explains "the before and after results are absolutely stunning, there is a visible reduction of wrinkles and more youthful and toned appearance. Viterol. A® has demonstrated remarkable effectiveness in reversing the signs of skin aging and is highly recommended as a gradual and continuous treatment".

Bill Lawler, M.D., a cosmetic surgeon with a 26-year history in aesthetics, witnessed the evolution of nearly all skin care products. " Viterol. A® does something completely different than other creams. While Botox is still the treatment of choice for deep furrows and certain types of wrinkles, Viterol. A® is the most effective topical treatment for fine lines that I have encountered in my practice. There is also a clearly visible improvement in skin smoothness and firmness," he said.

The greatest benefit of Viterol. A® is that it is a continuous and safe treatment the effect of which does not wear off.

* Viterol.A is recommended for men and women over the age of 30.

** Some irritation may occur at the beginning of treatment.

*** Viterol.A increases sensitivity to the sun and it is highly recommended to use sunscreen everyday during treatment.

VITEROL A FACE 40 g
VITEROL A FACE 20 g

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Echinacea: why does it work in real life but not in trials?
TopPreviousNext

Date: February 04, 2006 09:54 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Echinacea: why does it work in real life but not in trials?

The Wellness Revolution

Why clinical trials must take into account real dosage amounts!

You took it, and it worked. You’re one of legions of people all over the world who have found the little purple coneflower called Echinacea to be wonderfully effective in fighting colds. Echinacea is among the most popular herbal supplements in North America, accounting for 10% of herbal sales in the U.S.

So why are some in the scientific community saying it doesn’t work?

How Controversy Over a Little Flower

It was a July 2005 study done at the University of Edmonton in Canada, published in the pages of the New England Journal of Medicine, that fueled the fire of controversy. On one side, there’s the community of people who take Echinacea to ward off colds and other respiratory tract infections (staying well or getting better quickly tends to make enthusiastic and loyal followers). On the other side is a spate of studies, culminating in the July 2005, giving the thumbs down to the flower’s healing powers.

The much-touted study was a placebo-controlled trial and was double-blinded (neither test group knew what they were taking). Healthy college students were given a dose of a rhinovirus infection, and were then sent to individual dorm rooms to take either an extract of Echinacea or a placebo. The results were disappointing to those of us expecting the scientific community’s “proof” to match ours—based on what our bodies and senses tell us. The study found no statistically significant difference between severity of symptoms or duration of the rhinovirus between the Echinacea and the control group. Why didn’t the study results match those of so many individuals?

What went wrong?

Noted herbalist and author Roy Upton states, [“The studies which found] positive results had dosages which were consistent with herbalist recommendations.”]

The University of Edmonton study didn’t.

Two oft-cited clinical trials in which positive results were found in the use of Echinacea for the common cold, both in vivo and in human volunteers, have been conducted by researchers Vinti Goel.

Tiny Doses, Minuscule Amounts of Active Herb

It is widely agreed among herbalists that the trial—also conducted by the team at the University of Alberta, Canada—published in the New England Journal of Medicine in July 2005 used radically smaller doses than those traditionally taken, doses so small they couldn’t possibly have worked. In the Turner trial, Echinacea extracts were given in doses of 1.5 ml tid, equivalent to 900mg daily, if the conductors of trial had consulted the real-life herbalist, say the natural health care community, they could have run a test that would have, well, tested something. The usual prescription dose for Echinacea taken by mouth ranges from 500 to 1,000 milligrams per day, and is taken three to five times a day, for seven days. This creates a range of 1500 to 5,000 mg per day. Most studies have shown Echinacea to have the greatest effectiveness when one starts taking it immediately upon feeling the early symptoms of coming down with a cold or virus.

Importantly, Echinacea has been proven in many tests, including those by Bauer and Wagner, Foster, and Hobbs, to have a supportive effect upon the immune system. That Echinacea stimulates macrophages and killer cells is proven.

Sources:

Turner RB et al. New England Journal of Medicine, 2005 jul 28;353(4):341-8.

Upton R et al. Echinacea purpurea root: standards of analysis, Quality control, and therapeutics, American herbal pharmacopoeia, 2004

Goel v et al. Efficacy of standardized Echinacea preparation (echinilin) for the treatment of common cold: a randomized, double-blind, placebo- controlled trial. Journal of Clinical Pharmaceutical Therapy 2004: Feb,29(1):75-83.



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Cholesterol Support FAQ's
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Date: January 06, 2006 12:15 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Cholesterol Support FAQ's

Cholesterol Support FAQ's

What ingredients does NOW® Cholesterol Support contain, and how many capsules should I take daily?

NOW® Cholesterol Support is specially formulated to support your body’s normal metabolization of cholesterol. This supplement contains essential nutrients like Vitamins C & E, and Tocotrienols derived from natural source Vitamin E. The active ingredients include Chromium, Guggul Extract, and PureGar® Garlic, specialized dietary ingredients that work synergistically to support healthy cholesterol metabolism.

Has the formula for NOW® Cholesterol Support been changed?

Recently the U.S. FDA ruled that Red Rice Yeast extract has a drug effect on the body and has banned dietary supplements from containing this ingredient.

In order for NOW® to continue to offer Cholesterol Support with Red Rice Yeast extract, we would have to register this supplement as a drug, which would entail years of clinical trials. Due to the complications associated with this ingredient, NOW® has decided to reformulate this top seller. We’ve increased the levels of certain key nutrients to account for the absence of Red Rice Yeast extract, and this new formulation is as effective as the original. Disclaimer: This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

CHOLESTEROL SUPPORT 90 VCAPS 1 from NOW


Nutrition Info
Servings Per Container: 30
Serving Size: 3 Vcaps®
Amount Per Serving % Daily Value
Calories 5
Total Carbohydrate 1 g < 1%*
Dietary Fiber 0.5 g 2%
Vitamin C (from Ascorbyl Palmitate) 8 mg 12%
Vitamin E (as d-alpha Tocopherol) 18 IU 30%
Chromium (from Chromium Chelavite®) 200 mcg 170%
Pure-Gar®; Garlic (Allium sativum) 300 mg
Guar Gum (Cyamopsis tetragonoloba) (Seed) 300 mg
Guggul Extract (10% Guggulsterones) 220 mg
Tocotrienols (from Red Palm Oil) 33 mg
Alpha Tocotrienols 10 mg
Beta Tocotrienols 1 mg
Gamma Tocotrienols 17 mg
Delta Tocotrienols 5 mg
Policosanol (min. 60% Fatty Alcohol from Phytowaxes) 10 mg
* Percent Daily Values are based on 2,000 calorie diet.
† Daily Value not established.






Details

Serving Size: 3 Vcaps®

Suggested Use: As a dietary supplement, take 3 Vcaps® 2 times daily, preferably with meals.

Free of: salt, yeast, wheat, milk, soy or preservatives.

Other Ingredients: Cellulose (capsule), Maltodextrin, Gelatin, Silica and Magnesium Stearate (vegetable source).

Warnings: Not intended for pregnant or lactating women. Individuals currently using 'Statin' drugs should consult their health practitioner before using. Please discard the inedible freshness packet enclosed.


Recommended by Dr. James Balch, Cholesterol Support TM is a dietary supplement specifically formulated to support your body's natural metabolism of cholesterol.* In addition to this effective supplement, we recommend a diet low in saturated fats and regular aerobic exercise.




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Gr-8 Dophilus
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Date: December 29, 2005 12:06 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Gr-8 Dophilus

Did you know that poor digestive function is a contributing factor in more than ninety percent of America’s serious health issues?! The waiting rooms of doctors are jam packed, in part because so many people are suffering with gastrointestinal problems. The medical establishment and alternative health and wellness practitioners don’t always agree, but both sides are certain that a healthy digestive system is the cornerstone of good health. Proteins, the building blocks of life; carbohydrates and fats, your body’s source of energy; vitamins and minerals; and water – all are assimilated through digestion. If you’re not properly digesting the foods you eat, your body isn’t obtaining the nutrients it needs to repair, renew and thrive. Without the raw materials it needs to repair the damage we do to ourselves every day, your body begins to break down, leading to poor health and accelerated aging2,3.

While there are a multitude of factors involved in healthy digestive function, one of the most important is the delicate balance of bacteria found in the human gastrointestinal (GI) tract. There are three main types of flora in the human GI tract - Bifidobacteria, Bacteroides and Eubacterium. Of slightly less importance are Lactobacilli, Streptococci and Peptococci and other transitory flora1. Our stomachs and intestines are populated by hundreds of billions of these bacteria, or microflora. Amazingly, there are more probiotic organisms in our gut than there are cells in our bodies! That’s a lot of bacteria, but it’s GOOD bacteria, and each strain has specific functions in the human body. These bacteria aid the digestion of food and have protective qualities that contribute to good colon health. While a good balance of these different microflora is necessary, there are many factors that can, and do, disrupt this balance –certain medications, a poor diet, infection, stress, bad bacteria, aging and even the climate. The good news is a rapidly expanding body of research suggests that supplementing the diet with the right mix of microflora can have a beneficial affect on gastrointestinal function, and therefore overall health.

NOW® Gr8-Dophilus™ exclusively utilizes the finest strains from Rhodia Incorporated, the world’s leading supplier of high quality probiotic ingredients, and is enteric-coated to ensure that the bacteria in this product are not destroyed in stomach acid but reach the small and large intestines where they are most beneficial. Gr8-Dophilus is a vegetarian product that contains virtually no lactose.

Lactobacillus acidophilus is a well-studied microflora species that’s highly resistant to gastric acidity and is able to proliferate in the presence of bile. Like many probiotic organisms, it also adheres well to intestinal cells, helping to prevent the adherence of certain enteropathogens5.

Lactobacillus casei is a microflora strain that is found in the human mouth and intestines as well as in fermented vegetables, milk and meat. Recent research has shown that this bacterium is active in the GI tract and may help to modulate the immune system*. Research is continuing into this very promising probiotic.

Lactobacillus rhamnosus, like Lactobacillus acidophilus, is highly resistant to gastric acidity and proliferates well in bile. It, too, adheres well to intestinal cells. We’ve included this particular strain because it works extremely well with L. acidophilus. Lactobacillus salivarius is a strain that has proven highly effective against Helicobacter pylori, a bacterial species implicated in a number of digestive conditions. Studies have shown that L. salivarius is capable of producing high amounts of lactic acid, which has been shown to inhibit H. pylori growth in live subjects. Compared to other Lactobacillus strains, L. salivarius was proven to have the greatest inhibitory effect on the proliferation of H. pylori,4 which is why this strain is included in Gr8-Dophilus™.

Streptococcus thermophilus bacterium are isolated from yogurt and are recommended for lactose intolerant individuals to help digest lactose in the intestines. This strain is included in this formula to assist in the acidification of the intestinal environment, as well as to create a favorable environment for lactic acid bacteria.

Bifidobacterium bifidum is one of the workhorses of the large intestine. It has a high tolerance to gastric acidity, and, like L. acidophilus and many other probiotic organisms, it adheres well to intestinal cells, helping to prevent the adherence of certain enteropathogens5.

Bifidobacterium longum is a bifidobacterium of human origin that, like lactobacillus, is extremely resistant to gastric acid and bile salts. Because it’s anaerobic (able to live without oxygen) it’s perfectly suited to colonize the colon. Initial studies have shown that this particular strain of bifidobacteria helps to support the immune system*. It also seems to decrease enzymatic activity in feces. Researchers believe enzymatic activity in feces may contribute to carcinogenesis.

Bifidobacterium lactis is one of the most well-studied strains of probiotic bacteria, with a wealth of peer-reviewed, published research on its benefits. Clinical trials on B. lactis have shown it to be helpful in a number of digestive conditions, including diarrhea and lactose intolerance, as well as immune response modulation.

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Gr-8 Dophilus - PROBIOTICS & DIGESTIVE SUPPORT
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Date: December 29, 2005 12:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Gr-8 Dophilus - PROBIOTICS & DIGESTIVE SUPPORT

“PROBIOTICS & DIGESTIVE SUPPORT” Gr-8 Dophilus™

  • Complete Probiotic Supplement
  • Supports Digestive Health
  • Eight Beneficial Probiotic Strains
  • Guaranteed Potency & Purity

References
1) Brudnak, Mark A.; The Probiotic Solution: Nature’s Best-Kept Secret for Radiant Health, Dragon Door Publications, 2003
2) Various Authors; Functional Foods: Designer Foods, Pharmafoods, Nutraceuticals, Edited by Israel Goldberg; Chapman & Hall, Inc.; 1994
3) Tortora, Gerard J. & Grabowski, Sandra Reynolds; Principles of Anatomy and Physiology – Seventh Edition; Harper Collins, 1993
4) Drisko, J. et. al. Probiotics in health maintenance and disease prevention, Alternative Medicine Review, May, 2003
5) Playne, M. & Salminen, S. Health Benefits of Probiotics: Human studies and clinical trials, Nutrafoods, 2002



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Coenzyme Q10 and Cardiovascular Health.
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Date: December 13, 2005 11:34 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Coenzyme Q10 and Cardiovascular Health.

CoQ10 is a vitamin-like compound that is produced naturally in the human body and is also found in most living organisms. It is also called ubiquinone, a combination of quinone, a type of coenzyme, and ubiquitous, meaning it exists everywhere in the human body. CoQ10 plays an important role in your body’s energy production and is an essential component of the mitochondria, where it helps to metabolize fats and carbohydrates and maintain cell membrane flexibility. CoQ10 is also involved in the production of several key enzymes that are used to create ATP, which is burned by your body for energy, and used in the energy transfer between mitochondria and cells. Without CoQ10, you would not be able to function!

CoQ10 is also an effective antioxidant that may beneficially affect the aging process. As we age, our body’s production of CoQ10 declines by as much as 80 percent. Because it is so important to energy production, and therefore life, researchers believe that this decline may be a factor in the effects of aging on the human body. Clinical trials on both animal and human subjects have revealed a marked decrease in CoQ10 levels in relation to a wide variety of diseases. As a free radical scavenger, CoQ10 inhibits lipid peroxidation – a normal aspect of the aging process that is implicated in certain agerelated diseases. Studies conducted in the last fifteen years suggest CoQ10 is important for maintaining healthy intracellular activity, and some researchers have compared its efficiency to that of vitamin E, one of the most effective of all dietary antioxidants. Research has shown that CoQ10, along with glutathione and selenium, works to regenerate or recycle vitamin E after it’s capacity to fight radicals has been diminished, thereby allowing vitamin E to remain active as an antioxidant for a longer period of time in your body.

CoQ10 was first discovered by Dr. Frederick Crane of the University of Wisconsin in 1957. One year later, Professor Karl Folkers and others at Merck Inc. identified and recorded CoQ10’s chemical structure, and were the first to produce it through fermentation. Intermittent research led to its use in Japan for cardiac insufficiencies during the 1960’s. Dr. Folkers championed more intensive research into CoQ10’s role in cardiovascular health in 1972, after he and an Italian scientist, Gian Paolo Littarru, discovered that persons with cardiac insufficiencies had very low levels of CoQ10, and supplementation increased CoQ10 levels and positively affected heart health. Soon afterwards, the Japanese developed a method that allowed pure CoQ10 to be produced in quantities large enough for significant clinical trials. During the 1980’s this method was perfected in Japan, and medical technology finally allowed scientists to measure CoQ10 levels in blood and tissues, leading to a surge in further research. It was during this time that a Swedish researcher, Lars Ernster, drew attention to CoQ10’s role as a free radical-scavenging antioxidant. Today a multitude of research supports CoQ10’s health benefits.

As a result of the overwhelmingly positive reports from studies conducted since CoQ10’s discovery, the Japanese were the first to approve widespread use of CoQ10, granting market approval for it in 1974. From 1974 to 1982, CoQ10 use in Japan grew rapidly until it was one of the most widely used products in the Japanese pharmaceutical industry. It is still widely used today, and has a long history of safe use. In “An Introduction To Coenzyme Q10” by Peter H. Langsjoen, M.D., F.A.C.C., he lists the substantial amount of scientific evidence that supports CoQ10’s benefits. “Internationally, there have been at least nine placebo controlled studies on the treatment of heart disease with CoQ10: two in Japan, two in the United States, two in Italy, two in Germany, and one in Sweden. All nine of these studies have confirmed the effectiveness of CoQ10 as well as it’s remarkable safety. There have now been eight international symposia on the biomedical and clinical aspects of CoQ10 (from 1976 through 1993). These eight symposia comprised over 3000 papers presented by approximately 200 different physicians and scientists from 18 countries.”

“The majority of the clinical studies concerned the treatment of heart disease and were remarkably consistent in their conclusions: that treatment with CoQ10 significantly improved heart muscle function while producing no adverse effects or drug interactions.” There are many CoQ10 supplements on the market today, and it can be difficult to choose the best brand and dosage. CoQ10 is a fat-soluble substance, which means it is more easily absorbed and used by your body in the presence of fat. CoQ10 supplements that include lecithin or another dietary fat will be more effective, and CoQ10 in a softgel form should be in an oil base, usually soybean oil. The dosage most commonly used in research is 30 mg, but higher doses are optimal and may be required to maintain optimal levels as we age. Always remember to consult your health practitioner before taking dietary supplements if you have current health problems or are taking prescription medication.

Now Foods continues to be a leading supplier of high-quality, low cost CoQ10 products. In 1999 and 2003 NOW Foods CoQ10 was voted the best-selling brand in health food stores nationwide, earning the Vity Award from Vitamin Retailer magazine. NOW carries eight different effective potencies of CoQ10, ranging from 30mg to 400mg, in lonzenges, softgels, and vegetable capsules. Many of our formulas are complexed with other synergistic nutrients like vitamin E, selenium, lecithin, and hawthorn for greater absorption and efficiency.



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Life is more enjoyable when your stomach is prepared for it.
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Date: November 28, 2005 12:05 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Life is more enjoyable when your stomach is prepared for it.

PepZin GI for the stomach.

Life is more enjoyable when your stomach is prepared for it.

With the inevitable ups and downs of every day life, the importance of maintaining a healthy stomach is just good common sense. Because it is the immune system’s first line of defense, compromising the lining of the stomach could have a ripple effect in other parts of the body. Many things can impact the stomachs mucosal lining, including bacterial imbalances, poor metabolism of carbohydrates, too much aspirin, alcohol use, or just a spicy diet.

PepZinGI, from Doctor’s Best, is an exclusive, patented complex of zinc and l-carnosine that offers remarkable stomach support. A special chelated form of zinc that breaks down more slowly in the stomach, PepZinGI is able to exert its effects directly on the cells lining the stomach for a longer period of time. Clinical trials involving controlled, double-blind comparative studies of patients with gastric discomfort clearly demonstrated the superior ability of zinc-l-carnosine to help the body cope better. By helping to prevent free-radical damage, supporting cell growth and metabolism, and maintaining proper balance of bacteria in the stomach, PepZin GI can provide effective support of its crucial mucosal lining.*

*These statements have not been evaluated by the food and drug administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Pepzin GI 120VC from Doctors Best


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Q. How did researcher discover maitake’s health benefits?
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Date: November 11, 2005 06:22 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Q. How did researcher discover maitake’s health benefits?

Q. How did researcher discover maitake’s health benefits?

A. Because maitakes are well known as healthy food, researchers interested in medicinal mushrooms have studied them extensively. They discovered many maitake compounds with dramatic health-promoting potential. One of these compounds, maitake D-fraction, has particularly powerful anti-cancer effects.

In lab studies, D-fraction stops the growth of cancer cells and cancerous tumors. Maitake D-fraction stimulates the activity of two white blood cells, macrophages and natural killer cells. These white blood cells then trigger the production of interleukins and other lymphokines, two biochemicals that help mediate the immune response. Maitake also inhibits some of the mechanisms that promote metastasis, or spread, of cancer cells in the lymph system and bloodstream.

Because of this success, maitake D-fraction is now being used in preliminary clinical trials of women with breast cancer. One study has reported significant improvement of symptoms, including reduction of the tumor. The maitake D-fraction was given to breast cancer patients in addition to standard chemotherapy.

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Date: November 11, 2005 09:32 AM
Author: Darrell Miller (dm@vitanetonline.com)

Benefits of Omega-3 Fatty Acids

Cardiovascular Disease:
Numerous epidemiological and observational studies have shown that omega-3 fatty acids enriched diets are associated with reduction of cardiovascular mortality, myocardial infraction and sudden death. Higher fish intake was associated with decreased incidence of coronary artery disease and cardiovascular mortality in several prospective cohort studies. Putting it in prospective, a minimum of one fish meal a week was associated with a 52% reduction of sudden cardia death.

Randomized clinical trials are adding to the evidence that omega-3s are beneficial in cardiovascular disease, especially from secondary prevention of myocardial infraction.

One of the earliest randomized clinical trials was the diet and reinfraction trial (DART). This trial was designed to examine the effects of dietary intervention in the prevention of secondary myocardial infraction. The subjects advised to increase their intake of oily fish had a 29% reduction in 2-year all-cause mortality. This ovservation lead to the hypothesis that omega-3 fatty acids might protect the myocardium against acute ischemic stress. A post hoc analysis of patients receiving fish oil supplements (900mg/day of EPA and DHA) suggested that the protective effect was attributed to omega-3 fatty acids.

Another randomized placebo-controlled trial of patients admitted to the hospital with suspected acute myocardial infraction showed that supplementation with 1.8 g of omega-3 (EPA and DHA) for on year decreased total cardiac events by 29%. Both total cardiac death and nonfatal myocardial infractions were also reduced by 48%.

The largest randomized clinical trial to test the efficacy of omega-3 fatty acids for secondary prevention of cardiovascular disease is the GISSI-prevention study. From 1993 to 1995, 11,324 patients surviving myocardial infraction were randomly assigned either vitamin E (300mg daily, as synthetic-a-tocopherol), omega-3 fatty acids (1 g daily, standardized to 850 mg EPA and DHA), both or none. Compared with the control group, patients taking the fish oil showed a 15% reduction in the primary end point of death, nonfatal myocardial infraction, and nonfatal stroke. Patients supplementing with vitamin E online showed no benefit.

With this mounting data, the American Heart Association (AHA) recommends eathing at least two servings of fish per week (particularly fatty fish). The FDA has also announced a qualified health claim linking a reduced risk of coronary heart disease with the long-chain omega-3 polyunsaturated fatty acids.

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Omega-3 Fatty Acids - Part of Human diet for years.
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Date: November 09, 2005 09:25 AM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Omega-3 Fatty Acids - Part of Human diet for years.

Omega-3 fatty acids have been part of the human diet for some 2-4 million years during which our genes were adapting to our environment, including our diets. As with most important scientific breakthroughs, it all starts with an observation. In the early 1970’s, the Danish doctors, Hans Olaf Bang and Jorn Dyerberg, returned from a mission to Greenland reporting that cardiovascular disease were extremely rare among the Eskimos. This research opened the eyes of the medical world to the importance of a “new dietary factor: Marine Omega-3 fatty acids.

Omega-3 fatty acids (fish oil) have been studied for more than 30 years, resulting in more than 7,000 reports, nearly 900 human clinical trials. Omega-3 fatty acids have been shown to have positive effects on the heart, brain, joints, skin and even pregnancy. Studies have evaluated not only the multiple ways omega-3s promote cardiovascular health, but also the healthy functioning of many other biological activities.



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Research on SAMe....
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Date: October 26, 2005 12:49 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Research on SAMe....

Two groups of researchers have conducted analyses of trials that utilized SAM-e for mood enhancement. One meta-analysis was published in 1994. The researchers analyzed the efficacy of SAM-e in oral or injection forms based on published trials dated between 1973 and 1992. The authors concluded that there was a significant improvement of 17 to 38% seen in trials of SAM-e compared to placebo response. They state that the efficacy of SAM-e was superior to placebo and its administration caused few side effects.5 A second review was published in 2002. The authors analyzed studies in which SAM-e doses ranged from 200 to 1600 mg daily. They also found a significant effect of SAM-e in comparison to placebo, with an evident rapid onset of effect at enhancing mood.6

Promotes Joint Comfort and Mobility*

As a sulfur donor to connective tissue, SAM-e plays a major role in protecting the integrity of cartilage tissue. An in vitro trial assessed the actions of SAM-e in cultured human articular chondrocytes. At a concentration of 10 micrograms/ml, proteoglycan synthesis and sulfate residue incorporation in chondrocytes was shown to be 60% higher than control levels. Based on these results, it was shown that SAM-e has a positive influence on the growth and health of cartilaginous connective tissue.7

In a double-blind trial with 734 individuals with compromised joint health. SAM-e given orally at a dose of 1200 mg daily for 30 days was shown to significantly promote joint comfort compared to placebo, with a high level of tolerability and low incidence of side effects. The researchers concluded that SAM-e is a highly effective supplement for enhancing joint comfort.8

Another trial evaluated the response of individuals experiencing discomfort in the joints to a regimen of 1200 mg SAM-e for 1 week followed by 800 mg for the second week, and then 400 mg for weeks 3 through 8. This open trial of 20, 641 people showed a strong ability of SAM-e to enhance feelings of comfort within the joints. The treatment was rated as “very good” or “good” in 71% of the participants, with an additional 21% rating the treatment effect as “moderate”.9

In a long-term trial lasting 24 months, SAM-e was given to 108 participants with compromised joint function. Individuals were given 600 mg orally per day for the first two weeks followed by 400 mg daily for the remainder of the trial. Individuals experienced significant enhancements in joint comfort, with dramatic improvements noted after 2-4 weeks of treatment. Improvements continued to 6 months and beyond.10

In addition to the above studies, a review was conducted in 1987 to assess the results of SAM-e supplementation in clinical trials for enhancing joint mobility and function. Over 22,000 individuals had participated in the clinical trials that were the subject of this review. The author concluded from his analysis that SAM-e was shown to be highly efficacious, rivaling or surpassing the effectiveness of other treatments, and also possessing a high level of safety.11 Because of this, SAM-e may be the treatment of choice for enhancing joint function.

Supports Liver Health and Detoxification*

SAM-e supplementation can have profound benefits on liver function. These benefits center around its function as the major methyl donor in the liver, as well as its lipotropic activity. SAM-e also enhances the production of the antioxidant glutathione.

A number of trials have been conducted showing the ability of SAM-e to support liver detoxification functions and enhance liver health in individuals susceptible to toxin-induced liver compromise. SAM-e has the ability to normalize liver function by increasing the activity of enzymes needed to upregulate liver detoxification. These effects are comprehensive and rapid. Dosages used in these studies range from 600 mg to 1600 mg daily for 2 months to two years.12,13,14 In these trials, significant benefits of SAM-e supplementation were seen over placebo.

Safety

SAM-e has an excellent safety profile and is considered well-suited for long term use based on multiple clinical trials. Individuals diagnosed with manic depression should avoid SAM-e supplementation, as it may aggravate the manic phase *This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Scientific References

1. Agnoli A, Andreoli V, Casacchia M, Cerbo R. Effect of s-adenosyl-l-methionine (SAMe) upon depressive symptoms. J Psychiatr Res. 1976;13(1):43-54.

2. De Leo D. S-adenosylmethionine as an antidepressant. Curr Ther Research. 1987;41(6):865-70.

3. Kagan BL, Sultzer DL, Rosenlicht N,Gerner RH. Oral S-adenosylmethionine in depression: a randomized, double-blind, placebo-controlled trial. Am J Psychiatry. 1990 May;147(5):591-5.

4.Salmaggi P,Bressa GM,Nicchia G,Coniglio M,La Greca P,Le Grazie C.Doubleblind, placebo-controlled study of S-adenosyl-L-methionine in depressed postmenopausal women. Psychother Psychosom. 1993;59(1):34-40.

5. Bressa GM. S-adenosyl-l-methionine (SAMe) as antidepressant: metaanalysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14. 6.Mischoulon D, Fava M. Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence. Am J Clin Nutr. 2002 Nov;76(5):1158S-61S.

7. Harmand MF, Vilamitjana J,Maloche E, Duphil R, Ducassou D. Effects of Sadenosylmethionine on human articular chondrocyte differentiation. An in vitro study. Am J Med. 1987 Nov 20;83(5A):48-54.

8. Caruso I, . Italian double-blind multicenter study comparing S-adenosylmethionine, naproxen, and placebo in the treatment of degenerative joint disease. Am J Med. 1987 Nov 20;83(5A):66-71.

9. Berger R, Nowak H. A new medical approach to the treatment of osteoarthritis. Report of an open phase IV study with ademetionine (Gumbaral). Am J Med. 1987 Nov 20;83(5A):84-8.

10. Konig B. A long-term (two years) clinical trial with S-adenosylmethionine for the treatment of osteoarthritis. Am J Med. 1987 Nov 20;83(5A):89-94.

11. di Padova C. S-adenosylmethionine in the treatment of osteoarthritis. Review of the clinical studies. Am J Med. 1987 Nov 20;83(5A):60-5.

12. Frezza M, et al. S-adenosylmethionine counteracts oral contraceptive hepatotoxicity in women. Am J Med Sci. 1987; 293(4):234-238.

13. Frezza M, Surrenti C, Manzillo G, Fiaccadori F, Bortolini M, Di Padova C. Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study. Gastroenterology. 1990 Jul;99(1):211-5.

14. Mato JM, et al. S-adenosylmethionine in alcoholic liver cirrhosis: a randomized, placebo-controlled, double-blind, multicenter clinical trial. J Hepatol. 1999 Jun;30(6):1081-9.



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All SAM-e supplements are not created equal
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Date: October 26, 2005 12:41 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: All SAM-e supplements are not created equal

All SAM-e supplements are not created equal

During the manufacture of SAM-e, two forms are produced known as the S,S and the R,S isomers. The S,S isomer is the biologically active form in the human body, whereas the R,S form is considered to be inactive. Double Strength SAMe 400 utilizes Italian SAM-e to yield the highest available percentage of the active pure S,S form on the market. Double Strength SAMe 400 contains an average of nearly 80% of the active S,S form. Other SAM-e products contain as little as only 50% of the active form. A higher content of the active form yields a more potent product.

The molecule SAM-e itself is highly unstable. It will degrade quickly in conditions of heat, light and moisture. To increase its stability, it must be formed into a salt. It is important to note that SAM-e used for dietary supplements exists in a number of salt forms. Double Strength SAMe 400 utilizes the SAM-e tosylate disulfate salt form. This salt has been the most extensively utilized form in clinical trials of SAM-e.

Because of the unstable nature of pure SAM-e it is also highly susceptible to degradation in an acidic environment like the stomach. To be utilized effectively, it must pass through the stomach for absorption in the small intestine. For this reason, only enteric-coated formulas should be used. Double Strength SAMe 400 tablets are enteric-coated to maximize the utilization and benefit of the SAM-e by the body.

Benefits

Enhances Mood and Neural Function*

SAM-e has been studied for decades now for its potential role in enhancing mood and supporting healthy neural metabolism. In a double-blind placebo trial published in 1976, 30 individuals were given either SAM-e intramuscular injections (15 mg three times daily) or placebo. Individuals were assessed for improved mood and affect. It was found that 100% of patients in the SAMe group showed significant improvements in mood, while only 30% of the placebo group showed any improvement.1 The improvement seen with SAM-e in this trial was rapid, with a response time of between 4 and 7 days.

A second Italian double-blind placebo controlled study was published in 1987. Again, individuals showing signs of decreased affect and mood were administered 200 mg SAM-e as daily intramuscular injections, or a placebo, for four weeks. Each group consisted of 20 patients, with all medial and laboratory results being normal. Rating scales were used to monitor changes and the authors found that the treatment with SAM-e was significantly superior to placebo and was very well tolerated.2

Researchers had known that SAM-e injections showed benefit in mood enhancement based on the results of multiple clinical trials. However, with injections, chronic administration is always challenging. For this reason, oral doses are superior in terms of ease of administration. Studies were conducted to assess the efficacy of oral SAM-e preparations. One such study was published in 1990.

In this double-blind placebo-controlled trial, individuals were given increasing doses of SAM-e from 200 mg to 800 mg twice daily, or placebo, over the 21 day period of the trial. In the placebo group, one of the six individuals showed an enhancement of mood of 50% according to the rating scales, whereas 6 of the 9 individuals given the oral SAM-e showed a 50% or greater improvement in mood and affect.3 It was concluded that oral SAM-e, like SAM-e injections, can significantly enhance mood without significant side effects.

Another double-blind placebo controlled trial looked at the effects of administering 1600 mg of SAM-e, or placebo, daily to 80 women aged between 45 and 59. The administration took place for 30 days, after which the women were assessed for improvements. Rating scales were administered at 10 and 30 days. SAM-e supplementation significantly enhanced mood and affect in the women compared to placebo administration.4 SAM-e was also seen to be well tolerated, as three women in the placebo group and two women in the SAM-e group complained of minor side effects which did not interfere with continuation of treatment.



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PepZin GI™ helps relieve occasional discomfort.
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Date: September 20, 2005 05:40 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: PepZin GI™ helps relieve occasional discomfort.

PepZin GI™ helps relieve occasional discomfort.* CLINICAL TRIALS

In a randomized, multi-center, placebo-controlled double blind study, 299 patients suffering with symptoms of gastric discomfort were randomly allocated to receive either a zinc-L-carnosine complex or a placebo, or a control drug or its placebo for 8 weeks. Improvement ratings for a range of symptoms were taken at various points during the trial and compared with before treatment data. Of the 258 people who completed the trial, 136 were in the zinc-Lcarnosine group. Of the group, 92% of the participants were rated as “moderately improved” or better on an improvement scale across the category of symptoms including heartburn, tenderness, epigastric pain, diarrhea and constipation after 8 weeks.3

In another study, 28 patients with gastric discomfort were given a zinc-L-carnosine compound and monitored for 8 weeks. Improvement was rated on a scale of subjective and objective symptoms. After 4 weeks, the rate of those cases that were considered to be “significantly improved” was 68.4%. After eight weeks, the “significantly improved” number was 68.8%. Over 60% of these patients remained in the “significantly improved” category well after discontinuation of the treatment, suggesting a lasting effect of the zinc-L-carnosine compound beyond the time it is taken.4

Maintains a healthy GI environment.*

The mineral zinc in PepZin GI™ is a critical component to a number of physiological processes in our bodies. Some of these functions include growth and metabolism of cells, healing of wounds,and maintenance of carbohydrate and lipid metabolism.2

PepZin GI™ may also be able to favorably maintain the bacterial balance of the stomach and GI tract. Studies suggest that the zinc-L-carnosine co m pound may have effects on certain strains of harmful bacteria and, therefore, may be able to help maintain a GI environment that is favorable to health.1 By supporting the bacterial balance in the stomach, PepZin GI™ can help maintain a healthy mucosal lining.

Supports the health of gastric cells.*

PepZin GI™ has been studied for its ability to prevent free radical damage to gastric cells. In one such study, rat gastric cells were exposed to ethanol and hydrogen peroxide, two substances known to cause free radical damage to living cells. Cells were bathed in hydrogen peroxide, ethanol, zinc-L-carnosine, or a combination of zinc-L-carnosine with either ethanol or hydrogen peroxide. While the cells bathed in ethanol and hydrogen peroxide solutions all exhibited signs of damage due to free radical production, the cells that were bathed in zinc-L-carnosine were largely protected from the effects of free radical damage. The authors concluded that the zinc compound directly protected gastric mucosal cells from oxidant stress and alcohol induced damage.5

Additional research further confirms the gastro-protective effects of PepZin GI™. In another rat study, stomach lesions were induced by administration of the chemical monochloramine, a known pro-oxidant (producer of free radicals). One of the groups of rats was fed the zinc-Lcarnosine compound prior to being exposed to monochloramine. The researchers found that the size of the lesions in the group pre-treated with zinc-L-carnosine was significantly less than the lesions in the control group. The authors concluded that the zinc compound exerted a beneficial protective effect against monochloramine-induced stomach lesions.6

The zinc-L-carnosine in PepZin GI™ has also been shown to slow the development of aspirin induced stomach damage in rats. The researchers measurably detected lower levels of TNF-alpha in rats given zinc-L-carnosine as compared to the control rats. TNF-alpha is an inflammatory cytokine that is known to be released in response to gastric damage.7 These results may suggest a role for PepZin GI™ in protecting gastric cells by occasionally reducing the levels of certain cytokines in minor inflammation of the stomach.

Scientific References

1. Kuwayama H, et al. Polaprezinc. Nippon Rinsho 2002 Feb; 60 Suppl 2:717-720. 2.Matsukura T,Tanaka H. Applicability of zinc complex of l-carnosine for medical use. Biochemistry (Moscow) 2000;65(7):817-823. 3.Miyoshi A, et al. Clinical evaluation of Z-103 on gastric ulcer - a multicenter double-blind comparative study with cetraxate hydrochloride. Jpn PharmTher 1992;20(1):199-223. 4.Misawa T, et al. Clinical study of Z-103 - clinical effects on gastric ulcer and influence on endocrine function. Jpn PharmTher 1992; 20(1):245-254. 5. Hiraishi H, et al. Polaprezinc protects gastric mucosal cells from noxious agents through antioxidant properties in vitro. Aliment Pharmacl Ther 1999;13:261-269. 6. Kato S, Nishiwaki H, et al. Mucosal ulcerogenic action of monochloramine in rat stomachs: effects of polaprezinc and sucralfate. Dig Dis Sci 1997;42(10):2156-2163. 7.Naito Y, et al. Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-alpha expression in rats with aspirin-induced gastric mucosal injury. Dig Dis Sci 2001;46(4):845-851.



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Pumpkin Seed Oil "Cucurbita pepo"
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Date: August 18, 2005 12:14 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Pumpkin Seed Oil "Cucurbita pepo"

Pumpkin Seed Oil "Cucurbita pepo"

Definition: Pumpkin seeds have a significant antiparasitic property to them and are routinely used to rejuvenate the prostate gland. As a rich source of zinc, which is highly recommended for the male reproductive system. Pumpkin seeds are highly nutritional, but those who can not handle the seeds can take Pumpkin seed oil in Pill form. Pumpkin Seeds are a symbol of health in China.

Possible applications: Intestinal parasites, Prostate disorders.

Scientific info: Swedish clinical trials found the that oil constituents of pumpkin seed combined with saw palmetto treated an enlarged prostate gland effectively. Pumpkin seed has a reputation of being a non-irritating diuretic. Pumpkin seed contains a rare amino acid called myosin found in the seeds of certain Cucurbita species, which is the primary protein constituent of muscles.

Complementary supplements: quassia, buckthorn, acidophilus, bee pollen, bee propolis, B-complex, Saw palmetto, kelp, garlic, black walnut, red clover, cascara sagrada, vitamin E, bioflavonoids, phytonutrients, blue-green algae, zinc and electrolyte supplements.



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Depressed? Try these “super 5” supplements
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Date: August 09, 2005 03:25 PM
Author: Darrell Miller (dm@vitanetonline.com)
Subject: Depressed? Try these “super 5” supplements

Depressed? Try these “super 5” supplements

While we must first address basic health issues and tackle them individually, nature has provided us with a number of compounds capable of treatment depression by safely raising serotonin levels and by boosting oxygen supplies to brain cells.

1. 5-HTP, a metabolite of the amino acid tryptophan, has the ability to boost serotonin production without the negative side effects of drugs like Prozac. It has been successfully used in clinical trials with people suffering from depression that were resistant to traditional therapies. Because it can boost serotonin without the negative side effects of antidepressant drugs, it is one of nature’s best choices as a natural remedy for depression, anxiety and sleep disorders.

2. St. John’s worth as received considerable attention for its ability to successfully treat mild to moderate depression. Numerous studies have concluded that many patients respond as well or better to St. John’s wort than standard drugs. Not surprisingly, German doctors prescribe St. John’s wort four times as often as Prozac for depression.

3. Ginkgo has enjoyed tremendous popularity as an herb capable of boosting memory function. Because depression is viewed by some experts as a condition of brain under-stimulation, ginkgo may be valuable in that it can boost brain cell oxygenation by enhancing blood flow. A French study found that 166 patients with mental disorders significantly improved with ginkgo therapy.

4. Phenylalanine and Tyr osine are two amino acids which elevate serotonin levels and curb excess carbohydrate cravings. Dr. Oscar Janifer, M.D. in his book A Different Kind of Healing, comments: “I’ve had great results with tyrosine. It’s like a natural antidepressant and is a precursor to the neurotransmitter norepinephrine.” Phenylalanine acts as precursor to the amines that comprise neurotransmitters (serotonin) in the brain.

5 . NADH, a form of niacin, plays a vital role in the energy production of all cells and is thought to boost brain cell metabolism. It is currently used for Alzheimer’s disease and seems well suited to older individuals suffering fro m depression. NADH levels significantly decline with age.

Virtually any physical stressor can disrupt delicate chemical balances in the brain causing us to feel unexplainably sad for prolonged periods of time. Take a moment to evaluate your life, and look into natural means for assistance.



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